{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:09:33Z","timestamp":1792181373281,"version":"4.4.0"},"reference-count":31,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,11,1]]},"abstract":"<jats:p>OBJECTIVES. Double aortic arch is a common form of complete vascular ring, encircling both the trachea and esophagus, resulting in noncardiac morbidity. We sought to describe management and outcomes in a large single institution clinical series.<\/jats:p>\n                  <jats:p>PATIENTS AND METHODS. We reviewed the medical charts of all of the patients diagnosed with double aortic arch at age &amp;lt;18 years. Data regarding clinical presentation, anatomy, management, and outcomes were abstracted.<\/jats:p>\n                  <jats:p>RESULTS. We identified 81 patients (67% males) born between 1964 and 2005 and presenting at a median age of 5 months (range: birth to 10.3 years). Respiratory symptoms were present in 91%, including stridor in 77%. Gastrointestinal symptoms were present in 40%, with choking with feeds being most common. The dominant branch of the double aortic arch was right in 72%. Associated cardiac anomalies were present in 18%, with noncardiac anomalies in 7%. Repair was performed in 79 patients at a median age of 6 months. There were 2 deaths after surgical repair with no late deaths, with Kaplan-Meier survival estimates of 96% at 5 years. Postoperative complications included chylothorax in 9%. Only 1 patient required reoperation. The most common symptoms at most recent follow-up were respiratory (54%) followed by gastrointestinal symptoms (6%). Postoperative tracheal stenosis was documented in 14%, with tracheomalacia in 7%. There were no late reoperations and no evidence of aortic arch obstruction.<\/jats:p>\n                  <jats:p>CONCLUSIONS. Outcomes are excellent after repair of double aortic arch, although persistent respiratory symptoms are frequent and probably associated with previous compression-related maldevelopment of the trachea and major airways.<\/jats:p>","DOI":"10.1542\/peds.2006-1097","type":"journal-article","created":{"date-parts":[[2006,9,25]],"date-time":"2006-09-25T20:50:01Z","timestamp":1159217401000},"page":"e1336-e1341","source":"Crossref","is-referenced-by-count":163,"title":["Management and Outcomes of Double Aortic Arch in 81 Patients"],"prefix":"10.1542","volume":"118","author":[{"given":"Khalfan","family":"Alsenaidi","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Gurofsky","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"Karamlou","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William G.","family":"Williams","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian W.","family":"McCrindle","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2006,11,1]]},"reference":[{"key":"2021120823200750000_R1","doi-asserted-by":"crossref","unstructured":"Lima JA, Rosenblum BN, Reilly JS, Pennington DG, Nouri-Moghaddam S. 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