{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T18:03:15Z","timestamp":1780077795432,"version":"3.54.0"},"reference-count":18,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,5,1]]},"abstract":"<jats:p>Acute annular urticaria is a common and benign cutaneous hypersensitivity reaction seen in children that manifests with characteristic annular, arcuate, and polycyclic urticarial lesions in association with acral edema. It is mistaken most often for erythema multiforme and, occasionally, for a serum-sickness\u2013like reaction. Although these 3 entities may present in a similar manner, specific clinical features help to distinguish them, and it is important for the clinician to be able to differentiate among them. We present herein a series of 18 patients who were given a diagnosis of acute annular urticaria and review the clinical distinctions between acute annular urticaria, serum-sickness\u2013like reactions, and erythema multiforme. Because of the frequency of its clinical confusion with erythema multiforme, we propose the term \u201curticaria multiforme\u201d as a more apt description to highlight the distinctive clinical features of this urticaria variant.<\/jats:p>","DOI":"10.1542\/peds.2006-1553","type":"journal-article","created":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:51:38Z","timestamp":1177980698000},"page":"e1177-e1183","source":"Crossref","is-referenced-by-count":92,"title":["\u201cUrticaria Multiforme\u201d: A Case Series and Review of Acute Annular Urticarial Hypersensitivity Syndromes in Children"],"prefix":"10.1542","volume":"119","author":[{"given":"Kara N.","family":"Shah","sequence":"first","affiliation":[{"name":"Section of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Honig","sequence":"additional","affiliation":[{"name":"Section of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert C.","family":"Yan","sequence":"additional","affiliation":[{"name":"Section of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2007,5,1]]},"reference":[{"key":"2021120823355584600_R1","doi-asserted-by":"crossref","unstructured":"Tamayo-Sanchez L, Ruiz-Maldonado R, Laterza A. 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