{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:10:17Z","timestamp":1789783817512,"version":"4.0.1"},"reference-count":40,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,1,1]]},"abstract":"<jats:p>OBJECTIVES. Our objective was to determine the following among US pediatricians: (1) perceptions regarding burden of rotavirus disease and need for a vaccine; (2) intentions for recommending a newly licensed rotavirus vaccine; (3) perceived barriers to implementation; and (4) factors associated with plans for vaccine adoption.<\/jats:p>\n               <jats:p>PATIENTS AND METHODS. A network of 431 pediatricians was recruited from a random sample of American Academy of Pediatrics\u2019 members. The network was designed to be representative of the American Academy of Pediatrics with respect to region of the country, practice type, and practice setting. During January and February 2006, physicians were surveyed by Internet or mail. The survey contained a paragraph summarizing results of the new rotavirus vaccine trial. Respondents were asked about intentions to use the vaccine and anticipated barriers.<\/jats:p>\n               <jats:p>RESULTS. The survey response rate was 71%. Of the respondents, 52% strongly agreed and 37% somewhat agreed with the need for a rotavirus vaccine. If recommended for routine use, 50% would strongly recommend and 34% would recommend but not strongly; 52% would begin to use within 6 months and 27% from 6 months to 1 year. The top 3 \u201cdefinite\u201d barriers to implementation included concerns about uniform coverage of vaccine by insurers, lack of adequate reimbursement, and parental reluctance because of withdrawal of previous rotavirus vaccine. In multivariate analysis, factors associated with very likely adoption of the vaccine included perception of a high burden of rotavirus disease and a high level of confidence in prelicensure studies of vaccine safety. The presence of physician concerns about safety of the new vaccine and the perception of parental concerns about vaccine safety in general were negatively associated with adoption.<\/jats:p>\n               <jats:p>CONCLUSIONS. The majority of pediatricians reported willingness to implement the new rotavirus vaccine, most within 6 months. Major barriers to optimal implementation included provider concerns about reimbursement issues and parental acceptance of the vaccine.<\/jats:p>","DOI":"10.1542\/peds.2006-1874","type":"journal-article","created":{"date-parts":[[2007,1,3]],"date-time":"2007-01-03T15:47:33Z","timestamp":1167839253000},"page":"1-10","source":"Crossref","is-referenced-by-count":40,"title":["Will Pediatricians Adopt the New Rotavirus Vaccine?"],"prefix":"10.1542","volume":"119","author":[{"given":"Allison","family":"Kempe","sequence":"first","affiliation":[{"name":"Departments of Pediatrics"},{"name":"Preventive Medicine and Biometrics"},{"name":"Family Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew F.","family":"Daley","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics"},{"name":"Preventive Medicine and Biometrics"},{"name":"Family Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umesh D.","family":"Parashar","sequence":"additional","affiliation":[{"name":"Colorado Health Outcomes Program, University of Colorado at Denver and Health Sciences Center, Denver, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori A.","family":"Crane","sequence":"additional","affiliation":[{"name":"Family Medicine"},{"name":"Children\u2019s Outcomes Research Program, Children\u2019s Hospital, Denver, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda L.","family":"Beaty","sequence":"additional","affiliation":[{"name":"Preventive Medicine and Biometrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Stokley","sequence":"additional","affiliation":[{"name":"Epidemiology Branch, Division of Viral Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Barrow","sequence":"additional","affiliation":[{"name":"Family Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Babbel","sequence":"additional","affiliation":[{"name":"Family Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Miriam","family":"Dickinson","sequence":"additional","affiliation":[{"name":"Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc-Alain","family":"Widdowson","sequence":"additional","affiliation":[{"name":"Colorado Health Outcomes Program, University of Colorado at Denver and Health Sciences Center, Denver, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James P.","family":"Alexander","sequence":"additional","affiliation":[{"name":"Colorado Health Outcomes Program, University of Colorado at Denver and Health Sciences Center, Denver, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Berman","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics"},{"name":"Family Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2007,1,1]]},"reference":[{"key":"2021120902090117100_R1","doi-asserted-by":"crossref","unstructured":"Parashar UD, Hummelman EG, Bresee JS, Miller MA, Glass RI. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis.\u20082003;9:565\u2013572","DOI":"10.3201\/eid0905.020562"},{"key":"2021120902090117100_R2","doi-asserted-by":"crossref","unstructured":"Bresee JS, Glass RI, Ivanoff B, Gentsch JR. Current status and future priorities for rotavirus vaccine development, evaluation and implementation in developing countries. Vaccine.\u20081999;17:2207\u20132222","DOI":"10.1016\/S0264-410X(98)00376-4"},{"key":"2021120902090117100_R3","doi-asserted-by":"crossref","unstructured":"Parashar UD, Gibson CJ, Bresse JS, Glass RI. Rotavirus and severe childhood diarrhea. Emerg Infect Dis.\u20082006;12:304\u2013306","DOI":"10.3201\/eid1202.050006"},{"key":"2021120902090117100_R4","doi-asserted-by":"crossref","unstructured":"Fischer TK, Bresee JS, Glass RI. Rotavirus vaccines and the prevention of hospital-acquired diarrhea in children. Vaccine.\u20082004;22(suppl 1):S49\u2013S54","DOI":"10.1016\/j.vaccine.2004.08.017"},{"key":"2021120902090117100_R5","doi-asserted-by":"crossref","unstructured":"Tucker AW, Haddix AC, Bresee JS, Holman RC, Parashar UD, Glass RI. Cost-effectiveness analysis of a rotavirus immunization program for the United States. JAMA.\u20081998;279:1371\u20131376","DOI":"10.1001\/jama.279.17.1371"},{"key":"2021120902090117100_R6","unstructured":"Centers for Disease Control and Prevention. Rotavirus vaccine for the prevention of rotavirus gastroenteritis among children. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep.\u20081999;48(RR-2):1\u201320"},{"key":"2021120902090117100_R7","doi-asserted-by":"crossref","unstructured":"American Academy of Pediatrics, Committee on Infectious Diseases. Prevention of rotavirus disease: guidelines for use of rotavirus vaccine. Pediatrics.\u20081998;102:1483\u20131491","DOI":"10.1542\/peds.102.6.1483"},{"key":"2021120902090117100_R8","unstructured":"Centers for Disease Control and Prevention. Intussusception among recipients of rotavirus vaccine: United States, 1998\u20131999. MMWR Morb Mortal Wkly Rep.\u20081999;48:577\u2013581"},{"key":"2021120902090117100_R9","doi-asserted-by":"crossref","unstructured":"Kramarz P, France EK, Destefano F, et al. Population-based study of rotavirus vaccination and intussusception. Pediatr Infect Dis J.\u20082001;20:410\u2013416","DOI":"10.1097\/00006454-200104000-00008"},{"key":"2021120902090117100_R10","doi-asserted-by":"crossref","unstructured":"Murphy TV, Gargiullo PM, Massoudi MS, et al. Intussusception among infants given an oral rotavirus vaccine. N Engl J Med.\u20082001;344:564\u2013572","DOI":"10.1056\/NEJM200102223440804"},{"key":"2021120902090117100_R11","doi-asserted-by":"crossref","unstructured":"Parashar UD, Holman RC, Cummings KC, et al. Trends in intussusception-associated hospitalizations and deaths among US infants. Pediatrics.\u20082000;106:1413\u20131421","DOI":"10.1542\/peds.106.6.1413"},{"key":"2021120902090117100_R12","unstructured":"Centers for Disease Control and Prevention. Withdrawal of rotavirus vaccine recommendation. MMWR Morb Mortal Wkly Rep.\u20081999;48:1007"},{"key":"2021120902090117100_R13","doi-asserted-by":"crossref","unstructured":"Glass RI, Parashar UD. The promise of new rotavirus vaccines. N Engl J Med.\u20082006;354:75\u201377","DOI":"10.1056\/NEJMe058285"},{"key":"2021120902090117100_R14","doi-asserted-by":"crossref","unstructured":"Vesikari T, Matson DO, Dennehy P, et al. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med.\u20082006;354:23\u201333","DOI":"10.1056\/NEJMoa052664"},{"key":"2021120902090117100_R15","unstructured":"Ruiz-Palacios GM, Perez-Schael I, Velazquez FR, et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. N Engl J Med.\u20082006;354:11\u201322"},{"key":"2021120902090117100_R16","unstructured":"US Food and Drug Administration. FDA approves new vaccine to prevent rotavirus gastroenteritis in infants. Available at: www.fda.gov\/bbs\/topics\/news\/2006\/NEW01307.html. Accessed February 7, 2006"},{"key":"2021120902090117100_R17","unstructured":"Centers for Disease Control and Prevention. CDC\u2019s Advisory Committee recommends new vaccine to prevent rotavirus [press release]. Available at: www.cdc.gov\/nip\/news\/pr\/pr_rotavirus_feb2006.htm Accessed April 20, 2006"},{"key":"2021120902090117100_R18","unstructured":"American Academy of Pediatrics. AAP periodic survey (PS-51). Available at: www.aap.org\/research\/periodicsurvey\/psof.htm. Accessed February 6, 2006"},{"key":"2021120902090117100_R19","unstructured":"Crane LA, Daley MF, Beaty BL, et al. A sentinel physicians system as a technique for rapid turnaround immunization policy surveys. National Immunization Conference, Atlanta, GA, March 6\u20139, 2006. Available at: www.cdc.gov\/nip\/nic. Accessed February 6, 2006"},{"key":"2021120902090117100_R20","unstructured":"Glanz K, Lewis FM, Rimer BK. Health Behavior and Health Education: Theory, Research, and Practice. 3rd ed. San Francisco, CA: Jossey-Bass Inc; 2002"},{"key":"2021120902090117100_R21","doi-asserted-by":"crossref","unstructured":"Cooper A, Yusuf H, Rodewald L, Malik T, Pollard R, Pickering L. Attitudes, practices, and preferences of pediatricians regarding initiation of hepatitis B immunization at birth. Pediatrics.\u20082001;108(6). Available at: www.pediatrics.org\/cgi\/content\/full\/108\/6\/e98","DOI":"10.1542\/peds.108.6.e98"},{"key":"2021120902090117100_R22","doi-asserted-by":"crossref","unstructured":"Iwamoto M, Saari TN, McMahon SR, et al. A survey of pediatricians on the reintroduction of a rotavirus vaccine. Pediatrics.\u20082003;112. Available at: www.pediatrics.org\/cgi\/content\/full\/112\/1\/e6","DOI":"10.1542\/peds.112.1.e6"},{"key":"2021120902090117100_R23","doi-asserted-by":"crossref","unstructured":"Haupt RM, Isikci O, Kimble WL, Sotos GL, Fu J. Physicians\u2019 knowledge and attitudes about rotavirus gastroenteritis and rotavirus vaccine. Pediatr Ann.\u20082006;35:54\u201361","DOI":"10.3928\/0090-4481-20060101-15"},{"key":"2021120902090117100_R24","unstructured":"Centers for Disease Control and Prevention, Department of Health and Human Services. Rotavirus vaccine: what you need to know. Available at: www.cdc.gov\/nip\/publications\/VIS\/vis-rotavirus.pdf. Accessed June 28, 2006"},{"key":"2021120902090117100_R25","doi-asserted-by":"crossref","unstructured":"Davis MM, Ndiaye SM, Freed GL, Kim CS, Clark SJ. Influence of insurance status and vaccine cost on physicians\u2019 administration of pneumococcal conjugate vaccine. Pediatrics.\u20082003;112:521\u2013526","DOI":"10.1542\/peds.112.3.521"},{"key":"2021120902090117100_R26","unstructured":"Centers for Disease Control and Prevention. CDC vaccine price list. Available at: www.cdc.gov\/nip\/vfc\/cdc_vac_price_list.htm. Accessed April 20, 2006"},{"key":"2021120902090117100_R27","doi-asserted-by":"crossref","unstructured":"Schaffer SJ, Szilagyi PG, Shone LP, et al. Physician perspectives regarding pneumococcal conjugate vaccine. Pediatrics.\u20082002;110(6). Available at: www.pediatrics.org\/cgi\/content\/full\/110\/6\/e68","DOI":"10.1542\/peds.110.6.e68"},{"key":"2021120902090117100_R28","unstructured":"American Academy of Pediatrics. AAP efforts to enhance vaccine payment must comply with law: for the AAP Division of Health Care Finance and Quality Improvement. AAP News.\u20082005;26:40\u201341"},{"key":"2021120902090117100_R29","unstructured":"American Academy of Pediatrics Private Sector Advocacy Advisory Committee. The Business Case for Pricing New Vaccines. AAP Immunizations Initiatives Newsletters. 2005"},{"key":"2021120902090117100_R30","doi-asserted-by":"crossref","unstructured":"Glazner JE, Beaty BL, Pearson KA, Berman S. The cost of giving childhood vaccinations: differences among provider types. Pediatrics.\u20082004;113:1582\u20131587","DOI":"10.1542\/peds.113.6.1582"},{"key":"2021120902090117100_R31","unstructured":"Centers for Disease Control and Prevention. Updated recommendations on the use of pneumococcal conjugate vaccine in a setting of vaccine shortage: Advisory Committee on Immunization Practices. MMWR Morbid Mortal Wkly Rep.\u20082001;50:1140\u20131142"},{"key":"2021120902090117100_R32","unstructured":"Institute of Medicine, Committee on the Evaluation of Vaccine Purchase Financing in the United States. Financing Vaccines in the 21st Century Assuring Access and Availability. Washington, DC: National Academies Press; 2004"},{"key":"2021120902090117100_R33","doi-asserted-by":"crossref","unstructured":"Coleman MS, Sangrujee N, Zhou F, Chu S. Factors affecting U.S. manufacturers\u2019 decisions to produce vaccines. Health Aff (Millwood).\u20082005;24:635\u2013642","DOI":"10.1377\/hlthaff.24.3.635"},{"key":"2021120902090117100_R34","doi-asserted-by":"crossref","unstructured":"Simonsen L, Viboud C, Elixhauser A, Taylor RJ, Kapikian AZ. More on RotaShield and intussusception: the role of age at the time of vaccination. J Infect Dis.\u20082005;192(suppl 1):S36\u2013S43","DOI":"10.1086\/431512"},{"key":"2021120902090117100_R35","doi-asserted-by":"crossref","unstructured":"Luman ET, Barker LE, McCauley MM, Drews-Botsch C. Timeliness of childhood immunizations: a state-specific analysis. Am J Public Health.\u20082005;95:1367\u20131374","DOI":"10.2105\/AJPH.2004.046284"},{"key":"2021120902090117100_R36","doi-asserted-by":"crossref","unstructured":"Mell LK, Ogren DS, Davis RL, et al. Compliance with national immunization guidelines for children younger than 2 years, 1996\u20131999. Pediatrics.\u20082005;115:461\u2013467","DOI":"10.1542\/peds.2004-1891"},{"key":"2021120902090117100_R37","doi-asserted-by":"crossref","unstructured":"Ehrenkranz P, Lanata CF, Penny ME, Salazar-Lindo E, Glass RI. Rotavirus diarrhea disease burden in Peru: the need for a rotavirus vaccine and its potential cost savings. Rev Panam Salud Publica.\u20082001;10:240\u2013248","DOI":"10.1590\/S1020-49892001001000004"},{"key":"2021120902090117100_R38","doi-asserted-by":"crossref","unstructured":"Podewils LJ, Antil L, Hummelman E, Bresee J, Parashar UD, Rheingans R. Projected cost-effectiveness of rotavirus vaccination for children in Asia. J Infect Dis.\u20082005;192(suppl 1):S133\u2013S145","DOI":"10.1086\/431513"},{"key":"2021120902090117100_R39","doi-asserted-by":"crossref","unstructured":"Glass RI, Bresee JS, Turcios R, Fischer TK, Parashar UD, Steele AD. Rotavirus vaccines: targeting the developing world. J Infect Dis.\u20082005;192(suppl 1):S160\u2013S166","DOI":"10.1086\/431504"},{"key":"2021120902090117100_R40","doi-asserted-by":"crossref","unstructured":"Perez-Vargas J, Isa P, Lopez S, Arias CF. Rotavirus vaccine: early introduction in Latin America-risks and benefits. Arch Med Res.\u20082006;37:1\u201310","DOI":"10.1016\/j.arcmed.2005.06.004"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/119\/1\/1\/1118289\/zpe00107000001.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/119\/1\/1\/1118289\/zpe00107000001.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T09:34:58Z","timestamp":1639042498000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/119\/1\/1\/70780\/Will-Pediatricians-Adopt-the-New-Rotavirus-Vaccine"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1,1]]},"references-count":40,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2007,1,1]]},"published-print":{"date-parts":[[2007,1,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2006-1874","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1,1]]}}}