{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:59:28Z","timestamp":1761512368936,"version":"3.40.5"},"reference-count":36,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,3,1]]},"abstract":"<jats:p>Cat-scratch disease is a common disease, occurring in an estimated 24000 patients annually in the United States, and is one of the most common causes of chronic lymphadenitis in children. A wide array of neurologic complications occurs as a result of cat-scratch disease. However, there have been no reports of acute-onset, self-resolving, recurrent, expressive aphasia, as we report here in an adolescent boy. In our case, establishing the diagnosis of cat-scratch encephalopathy saved time and resources and afforded the family a benign diagnosis. Cat-scratch encephalopathy must be considered in the differential diagnoses when pediatric patients present with unusual neurologic symptoms.<\/jats:p>","DOI":"10.1542\/peds.2006-1885","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T05:39:09Z","timestamp":1172813949000},"page":"e760-e763","source":"Crossref","is-referenced-by-count":8,"title":["Recurrent Expressive Aphasia as a Presentation of Cat-Scratch Encephalopathy"],"prefix":"10.1542","volume":"119","author":[{"given":"James W.","family":"Fox","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Emergency Medicine, Children\u2019s Hospital of Akron, Akron, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna K.","family":"Studley","sequence":"additional","affiliation":[{"name":"Department of Pediatrics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine, Columbus Children\u2019s Hospital, Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2007,3,1]]},"reference":[{"key":"2021120901531569600_R1","doi-asserted-by":"crossref","unstructured":"Greer WER, Keefer CS. Cat-scratch fever: a disease entity. N Engl J Med.\u20081951;244:545\u2013548","DOI":"10.1056\/NEJM195104122441503"},{"key":"2021120901531569600_R2","unstructured":"Debre R, Lamy M, Jamment ML, Costil L, Mozziconacci P. Cat scratch disease [in French]. Sem Hop.\u20081950;26:1895\u20131904"},{"key":"2021120901531569600_R3","doi-asserted-by":"crossref","unstructured":"Carithers HA. Cat-scratch disease: an overview based on a study of 1,200 patients. Am J Dis Child.\u20081985;139:1124\u20131133","DOI":"10.1001\/archpedi.1985.02140130062031"},{"key":"2021120901531569600_R4","doi-asserted-by":"crossref","unstructured":"Carithers HA, Margileth AM. Cat-scratch disease: acute encephalopathy and other neurologic manifestations. Am J Dis Child.\u20081991;145:98\u2013101","DOI":"10.1001\/archpedi.1991.02160010104026"},{"key":"2021120901531569600_R5","unstructured":"De-Long X, Zeng W, Yong-jian S. Cat-scratch disease encephalopathy. Chin Med J (Engl).\u20081994;107:104\u2013106"},{"key":"2021120901531569600_R6","doi-asserted-by":"crossref","unstructured":"Selby G, Walker GL. Cerebral arteritis in cat-scratch disease. Neurology.\u20081979;29:1413\u20131418","DOI":"10.1212\/WNL.29.10.1413"},{"key":"2021120901531569600_R7","doi-asserted-by":"crossref","unstructured":"Pickerill RG, Milder JE. Transverse myelitis associated with cat-scratch disease in an adult. JAMA.\u20081981;246:2840\u20132841","DOI":"10.1001\/jama.246.24.2840"},{"key":"2021120901531569600_R8","doi-asserted-by":"crossref","unstructured":"Lewis DW, Tucker SH. Central nervous system involvement in cat scratch disease. Pediatrics.\u20081986;77:714\u2013721","DOI":"10.1542\/peds.77.5.714"},{"key":"2021120901531569600_R9","doi-asserted-by":"crossref","unstructured":"Harvey RA, Misselbeck WJA, Uphold RE. Cat-scratch disease: an unusual cause of combative behavior. Am J Emerg Med.\u20081991;9:52\u201353","DOI":"10.1016\/0735-6757(91)90016-D"},{"key":"2021120901531569600_R10","doi-asserted-by":"crossref","unstructured":"Tsao CY. Generalized tonic-clonic status epilepticus in a child with cat-scratch disease and encephalopathy. Clin Electroencephalogr.\u20081992;23:65\u201367","DOI":"10.1177\/155005949202300204"},{"key":"2021120901531569600_R11","doi-asserted-by":"crossref","unstructured":"Hahn JS, Sum JM, Lee KP. Unusual MRI findings after status epilepticus due to cat-scratch disease. Pediatr Neurol.\u20081994;10:255\u2013258","DOI":"10.1016\/0887-8994(94)90035-3"},{"key":"2021120901531569600_R12","doi-asserted-by":"crossref","unstructured":"Hachimi-Idrissi S, Goossens A, Pierard D, Frankx J, Corne L. Severe encephalopathy in a child: an uncommon cause. Eur J Emerg Med.\u20081998;5:461\u2013463","DOI":"10.1097\/00063110-199812000-00014"},{"key":"2021120901531569600_R13","doi-asserted-by":"crossref","unstructured":"Easley RB, Cooperstock MS, Tobias JD. Cat-scratch disease causing status epilepticus in children. South Med J.\u20081999;92:73\u201376","DOI":"10.1097\/00007611-199901000-00015"},{"key":"2021120901531569600_R14","doi-asserted-by":"crossref","unstructured":"Steiner MM, Vuckovitch D, Hadawi SA. Cat-scratch disease with encephalopathy. J Pediatr.\u20081963;62:514\u2013520","DOI":"10.1016\/S0022-3476(63)80008-6"},{"key":"2021120901531569600_R15","doi-asserted-by":"crossref","unstructured":"Hindle J, Pearce JMS. Cerebellar encephalopathy in cat scratch disease. J Neurol Neurosurg Psychiatry.\u20081987;50:936","DOI":"10.1136\/jnnp.50.7.936"},{"key":"2021120901531569600_R16","doi-asserted-by":"crossref","unstructured":"Walter RS, Eppes SC. Cat scratch disease presenting with peripheral facial nerve paralysis. Pediatrics.\u20081998;101(5). Available at: www.pediatrics.org\/cgi\/content\/full\/101\/5\/e13","DOI":"10.1542\/peds.101.5.e13"},{"key":"2021120901531569600_R17","doi-asserted-by":"crossref","unstructured":"Rocha JL, Pellegrino LN, Riella LV, Martins LT. Acute hemiplegia associated with cat-scratch disease. Braz J Infect Dis.\u20082004;8:263\u2013266","DOI":"10.1590\/S1413-86702004000300012"},{"key":"2021120901531569600_R18","doi-asserted-by":"crossref","unstructured":"Chan L, Reilly KM, Snyder HS. An unusual presentation of cat scratch encephalitis. J Emerg Med.\u20081995;13:769\u2013772","DOI":"10.1016\/0736-4679(95)02017-9"},{"key":"2021120901531569600_R19","doi-asserted-by":"crossref","unstructured":"Anbu AT. Basal ganglia involvement in a child with cat-scratch disease. Pediatr Infect Dis J.\u20082003;22:931\u2013933","DOI":"10.1097\/01.inf.0000091384.09278.7d"},{"key":"2021120901531569600_R20","doi-asserted-by":"crossref","unstructured":"Puligheddu M, Giagheddu A, Genugu F, Giagheddu M, Marrosu F. Epilepsia partialis continua in cat scratch disease [published correction appears in Seizure. 2006;15:357]. Seizure.\u20082004;13:191\u2013195","DOI":"10.1016\/S1059-1311(03)00159-6"},{"key":"2021120901531569600_R21","doi-asserted-by":"crossref","unstructured":"Revol A, Vighetto A, Jouvet A, Aimard G, Trillet M. Encephalitis in cat scratch disease with persistent dementia. J Neurol Neurosurg Psychiatry.\u20081992;55:133\u2013135","DOI":"10.1136\/jnnp.55.2.133"},{"key":"2021120901531569600_R22","doi-asserted-by":"crossref","unstructured":"Adal KA, Cockerell CJ, Petri WA Jr. Cat scratch disease bacillary angiomatosis, and other infections due to Rochalimaea. N Engl J Med.\u20081994;330:1509\u20131515","DOI":"10.1056\/NEJM199405263302108"},{"key":"2021120901531569600_R23","doi-asserted-by":"crossref","unstructured":"Hadley S, Albrecht MA, Tarsy D. Cat-scratch encephalopathy: a cause of status epilepticus and coma in a young healthy adult. Neurology.\u20081995;45:196","DOI":"10.1212\/WNL.45.1.196"},{"key":"2021120901531569600_R24","doi-asserted-by":"crossref","unstructured":"Pollen RH. Cat-scratch encephalitis. Neurology.\u20081968;18:1031\u20131033","DOI":"10.1212\/WNL.18.10.1031"},{"key":"2021120901531569600_R25","doi-asserted-by":"crossref","unstructured":"Noyola DE, Holder DL, Fishman MA, Edwards MS. Recurrent encephalopathy in cat-scratch disease. Pediatr Infect Dis J.\u20081999;18:567\u2013568","DOI":"10.1097\/00006454-199906000-00024"},{"key":"2021120901531569600_R26","doi-asserted-by":"crossref","unstructured":"Lyon LW. Neurologic manifestations of cat-scratch disease: report of a case and review of the literature. Arch Neurol.\u20081971;25:23\u201327","DOI":"10.1001\/archneur.1971.00490010033004"},{"key":"2021120901531569600_R27","doi-asserted-by":"crossref","unstructured":"Hamilton GN, Matthews T. Aphasia: the sole manifestation of focal status epilepticus. Neurology.\u20081979;29:745\u2013748","DOI":"10.1212\/WNL.29.5.745"},{"key":"2021120901531569600_R28","doi-asserted-by":"crossref","unstructured":"Dinner DS, Lueders H, Lederman R, Gretter TE. Aphasic status epilepticus: a case report. Neurology.\u20081981;31:888\u2013890","DOI":"10.1212\/WNL.31.7.888"},{"key":"2021120901531569600_R29","doi-asserted-by":"crossref","unstructured":"Wells CR, Labar DR, Solomon GE. Aphasia as the sole manifestation of simple partial status epilepticus. Epilepsia.\u20081992;33:84\u201387","DOI":"10.1111\/j.1528-1157.1992.tb02286.x"},{"key":"2021120901531569600_R30","doi-asserted-by":"crossref","unstructured":"Kirshner HS, Hughes T, Fakhoury T, Abou-Khalil B. Aphasia secondary to partial status epilepticus of the basal temporal language area. Neurology.\u20081995;45:1616\u20131618","DOI":"10.1212\/WNL.45.8.1616"},{"key":"2021120901531569600_R31","doi-asserted-by":"crossref","unstructured":"Primavera A, Gianelli MV, Bandini F. Aphasic status epilepticus in multiple sclerosis. Eur Neurol.\u20081996;36:374\u2013377","DOI":"10.1159\/000117296"},{"key":"2021120901531569600_R32","doi-asserted-by":"crossref","unstructured":"Grimes DA, Guberman A. De novo aphasic status epilepticus. Epilepsia.\u20081997;38:945\u2013949","DOI":"10.1111\/j.1528-1157.1997.tb01262.x"},{"key":"2021120901531569600_R33","doi-asserted-by":"crossref","unstructured":"DeToledo JC, Minagar A, Lowe MR. Persisting aphasia as the sole manifestation of partial status epilepticus. Clin Neurol Neurosurg.\u20082000;102:144\u2013148","DOI":"10.1016\/S0303-8467(00)00091-3"},{"key":"2021120901531569600_R34","doi-asserted-by":"crossref","unstructured":"Hasegawa T, Shiga Y, Narikawa K, et al. Periodic episodes of aphasia as an unusual manifestation of partial status epilepticus. J Clin Neurosci.\u20082005;12:820\u2013822","DOI":"10.1016\/j.jocn.2004.09.024"},{"key":"2021120901531569600_R35","doi-asserted-by":"crossref","unstructured":"Weston KD, Tran T, Kimmel KN, Maria BL. Possible role of high-dose corticosteroids in the treatment of cat-scratch disease encephalopathy. J Child Neurol.\u20082001;16:762\u2013763","DOI":"10.1177\/088307380101601010"},{"key":"2021120901531569600_R36","doi-asserted-by":"crossref","unstructured":"Marra CM. Neurologic complications of Bartonella henselae infection. Curr Opin Neurol.\u20081995;8:164\u2013169","DOI":"10.1097\/00019052-199506000-00002"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/119\/3\/e760\/1112569\/zpe0030700e760.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/119\/3\/e760\/1112569\/zpe0030700e760.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T20:45:31Z","timestamp":1683751531000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/119\/3\/e760\/70417\/Recurrent-Expressive-Aphasia-as-a-Presentation-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,1]]},"references-count":36,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2007,3,1]]},"published-print":{"date-parts":[[2007,3,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2006-1885","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"type":"print","value":"0031-4005"},{"type":"electronic","value":"1098-4275"}],"subject":[],"published":{"date-parts":[[2007,3,1]]}}}