{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T13:06:20Z","timestamp":1746709580690,"version":"3.40.5"},"reference-count":22,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,8,1]]},"abstract":"<jats:p>A 12-month-old girl with occult bacterial meningitis presented with a simple febrile seizure. On examination, the patient was alert, interactive, and smiling responsively without meningeal signs, focal neurologic findings, or signs of extreme illness. Her parents were reluctant to allow a lumbar puncture, and the patient was admitted for observation without lumbar puncture. Her fever resolved, and she was playful, had good oral intake, and was discharged 24 hours after admission. Her initial blood-culture result remained negative. Within 24 hours of discharge, the patient had a focal febrile seizure, came back to the hospital, and was found to have meningitis with a penicillin-susceptible, nonvaccine Streptococcus pneumoniae strain 12F.<\/jats:p>","DOI":"10.1542\/peds.2006-2727","type":"journal-article","created":{"date-parts":[[2007,7,24]],"date-time":"2007-07-24T00:54:14Z","timestamp":1185238454000},"page":"e428-e431","source":"Crossref","is-referenced-by-count":8,"title":["Pneumococcal Meningitis Presenting With a Simple Febrile Seizure and Negative Blood-Culture Result"],"prefix":"10.1542","volume":"120","author":[{"given":"Allison","family":"Golnik","sequence":"first","affiliation":[{"name":"Division of General Pediatrics, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2007,8,1]]},"reference":[{"key":"2021120901493423900_R1","doi-asserted-by":"crossref","unstructured":"Offringa M, Beishuizen A, Derksen-Lubsen G, Lubsen J. Seizures and fever: can we rule out meningitis on clinical grounds alone?Clin Pediatr (Phila).\u20081992;31:514\u2013522","DOI":"10.1177\/000992289203100901"},{"key":"2021120901493423900_R2","doi-asserted-by":"crossref","unstructured":"Joffe A, McCormick M, DeAngelis C. Which children with febrile seizures need lumbar puncture? A decision analysis approach. Am J Dis Child.\u20081983;137:1153\u20131156","DOI":"10.1001\/archpedi.1983.02140380013005"},{"key":"2021120901493423900_R3","doi-asserted-by":"crossref","unstructured":"Lorber J, Sunderland R. Lumbar puncture in children with convulsions associated with fever. Lancet.\u20081980;1(8172):785\u2013786","DOI":"10.1016\/S0140-6736(80)91290-8"},{"key":"2021120901493423900_R4","doi-asserted-by":"crossref","unstructured":"Al-Eissa YA. Lumbar puncture in the clinical evaluation of children with seizures associated with fever. Pediatr Emerg Care.\u20081995;11:347\u2013350","DOI":"10.1097\/00006565-199512000-00004"},{"key":"2021120901493423900_R5","doi-asserted-by":"crossref","unstructured":"Green SM, Rothrock SG, Clem KJ, Zurcher RF, Mellick L. Can seizures be the sole manifestation of meningitis in febrile children?Pediatrics.\u20081993;92:527\u2013534","DOI":"10.1542\/peds.92.4.527"},{"key":"2021120901493423900_R6","doi-asserted-by":"crossref","unstructured":"Carroll W, Brookfield D. Lumbar puncture following febrile convulsion. Arch Dis Child.\u20082002;87:238\u2013240","DOI":"10.1136\/adc.87.3.238"},{"key":"2021120901493423900_R7","doi-asserted-by":"crossref","unstructured":"Trainor JL, Hampers LC, Krug SE, Listernick R. Children with first-time simple febrile seizures are at low risk of serious bacterial illness. Acad Emerg Med.\u20082001;8:781\u2013787","DOI":"10.1111\/j.1553-2712.2001.tb00207.x"},{"key":"2021120901493423900_R8","doi-asserted-by":"crossref","unstructured":"Offringa M, Moyer VA. Evidence based paediatrics: evidence based management of seizures associated with fever. BMJ.\u20082001;323:1111\u20131114","DOI":"10.1136\/bmj.323.7321.1111"},{"key":"2021120901493423900_R9","doi-asserted-by":"crossref","unstructured":"Kaplan SL, Mason EO Jr, Wald ER, et al. Decrease of invasive pneumococcal infections in children among 8 children's hospitals in the United States after the introduction of the 7-valent pneumococcal conjugate vaccine. Pediatrics.\u20082004;113:443\u2013449","DOI":"10.1542\/peds.113.3.443"},{"key":"2021120901493423900_R10","doi-asserted-by":"crossref","unstructured":"Steenhoff AP, Shah SS, Ratner AJ, Patil SM, McGowan KL. Emergence of vaccine-related pneumococcal serotypes as a cause of bacteremia. Clin Infect Dis.\u20082006;42:907\u2013914","DOI":"10.1086\/500941"},{"key":"2021120901493423900_R11","doi-asserted-by":"crossref","unstructured":"Poehling KA, Talbot TR, Griffin MR, et al. Invasive pneumococcal disease among infants before and after introduction of pneumococcal conjugate vaccine. JAMA.\u20082006;295:1668\u20131674","DOI":"10.1001\/jama.295.14.1668"},{"key":"2021120901493423900_R12","doi-asserted-by":"crossref","unstructured":"Black SB, Shinefield HR, Hansen J, Elvin L, Laufer D, Malinoski F. Postlicensure evaluation of the effectiveness of seven valent pneumococcal conjugate vaccine. Pediatr Infect Dis J.\u20082001;20:1105\u20131107","DOI":"10.1097\/00006454-200112000-00002"},{"key":"2021120901493423900_R13","doi-asserted-by":"crossref","unstructured":"Whitney CG, Farley MM, Hadler J, et al. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. N Engl J Med.\u20082003;348:1737\u20131746","DOI":"10.1056\/NEJMoa022823"},{"key":"2021120901493423900_R14","doi-asserted-by":"crossref","unstructured":"Gonzalez BE, Hulten KG, Lamberth L, Kaplan SL, Mason EO Jr. Streptococcus pneumoniae serogroups 15 and 33: an increasing cause of pneumococcal infections in children in the United States after the introduction of the pneumococcal 7-valent conjugate vaccine. Pediatr Infect Dis J.\u20082006;25:301\u2013305","DOI":"10.1097\/01.inf.0000207484.52850.38"},{"key":"2021120901493423900_R15","unstructured":"American Academy of Pediatrics, Provisional Committee on Quality Improvement, Subcommittee on Febrile Seizures. Practice parameter: the neurodiagnostic evaluation of the child with a first simple febrile seizure. Pediatrics.\u20081996;97:769\u2013772; discussion 773\u2013765"},{"key":"2021120901493423900_R16","doi-asserted-by":"crossref","unstructured":"Nozicka C. Lumbar puncture and the first simple febrile seizure. Pediatrics.\u20081997;99:306\u2013307","DOI":"10.1542\/peds.99.2.306a"},{"key":"2021120901493423900_R17","doi-asserted-by":"crossref","unstructured":"Ratcliffe JC, Wolf SM. Febrile convulsions caused by meningitis in young children. Ann Neurol.\u20081977;1:285\u2013286","DOI":"10.1002\/ana.410010316"},{"key":"2021120901493423900_R18","doi-asserted-by":"crossref","unstructured":"Rutter N, Smales OR. Role of routine investigations in children presenting with their first febrile convulsion. Arch Dis Child.\u20081977;52:188\u2013191","DOI":"10.1136\/adc.52.3.188"},{"key":"2021120901493423900_R19","doi-asserted-by":"crossref","unstructured":"Trautner BW, Caviness AC, Gerlacher GR, Demmler G, Macias CG. Prospective evaluation of the risk of serious bacterial infection in children who present to the emergency department with hyperpyrexia (temperature of 106 degrees F or higher). Pediatrics.\u20082006;118:34\u201340","DOI":"10.1542\/peds.2005-2823"},{"key":"2021120901493423900_R20","doi-asserted-by":"crossref","unstructured":"Bohr V, Rasmussen N, Hansen B, et al. 875 cases of bacterial meningitis: diagnostic procedures and the impact of preadmission antibiotic therapy. Part III of a three-part series. J Infect.\u20081983;7:193\u2013202","DOI":"10.1016\/S0163-4453(83)96980-3"},{"key":"2021120901493423900_R21","doi-asserted-by":"crossref","unstructured":"Coant PN, Kornberg AE, Duffy LC, Dryja DM, Hassan SM. Blood culture results as determinants in the organism identification of bacterial meningitis. Pediatr Emerg Care.\u20081992;8:200\u2013205","DOI":"10.1097\/00006565-199208000-00006"},{"key":"2021120901493423900_R22","doi-asserted-by":"crossref","unstructured":"Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Diseases. 2nd ed. Philadelphia, PA: Harcourt Publishers Ltd; 2003","DOI":"10.1097\/00024382-200307000-00020"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/120\/2\/e428\/1119681\/zpe0080700e428.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/120\/2\/e428\/1119681\/zpe0080700e428.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T14:20:00Z","timestamp":1683987600000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/120\/2\/e428\/70333\/Pneumococcal-Meningitis-Presenting-With-a-Simple"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,1]]},"references-count":22,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2007,8,1]]},"published-print":{"date-parts":[[2007,8,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2006-2727","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"type":"print","value":"0031-4005"},{"type":"electronic","value":"1098-4275"}],"subject":[],"published":{"date-parts":[[2007,8,1]]}}}