{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T02:24:30Z","timestamp":1784255070765,"version":"3.55.0"},"reference-count":46,"publisher":"American Academy of Pediatrics (AAP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,4,1]]},"abstract":"<jats:p>OBJECTIVE. The goal was to examine the association between early childhood neglect (birth to age 2 years) and later childhood aggression at ages 4, 6, and 8 years, compared with aggression's associations with early childhood abuse and later abuse and neglect.<\/jats:p><jats:p>METHODS. A prospective cohort of 1318 predominantly at-risk children, recruited from 4 US cities and 1 southern state, were monitored from birth to 8 years of age. Maltreatment was determined through review of local child protective services records. A hierarchical, linear model approach, a special case of general, linear, mixed modeling, was used to predict aggressive behavior scores, as reported by the child's primary caregiver at ages 4, 6, and 8 years.<\/jats:p><jats:p>RESULTS. Only early neglect significantly predicted aggression scores. Early abuse, later abuse, and later neglect were not significantly predictive in a controlled model with all 4 predictors.<\/jats:p><jats:p>CONCLUSION. This longitudinal study suggests that child neglect in the first 2 years of life may be a more-important precursor of childhood aggression than later neglect or physical abuse at any age.<\/jats:p>","DOI":"10.1542\/peds.2006-3622","type":"journal-article","created":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T20:25:58Z","timestamp":1207081558000},"page":"725-731","source":"Crossref","is-referenced-by-count":129,"title":["Importance of Early Neglect for Childhood Aggression"],"prefix":"10.1542","volume":"121","author":[{"given":"Jonathan B.","family":"Kotch","sequence":"first","affiliation":[{"name":"Departments of Maternal and Child Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terri","family":"Lewis","sequence":"additional","affiliation":[{"name":"Biostatistics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon M.","family":"Hussey","sequence":"additional","affiliation":[{"name":"Departments of Maternal and Child Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"English","sequence":"additional","affiliation":[{"name":"Washington State Department of Social and Health Services, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Thompson","sequence":"additional","affiliation":[{"name":"Juvenile Protective Association, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan J.","family":"Litrownik","sequence":"additional","affiliation":[{"name":"Department of Psychology, San Diego State University, San Diego, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desmond K.","family":"Runyan","sequence":"additional","affiliation":[{"name":"Social Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrikant I.","family":"Bangdiwala","sequence":"additional","affiliation":[{"name":"Biostatistics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benyamin","family":"Margolis","sequence":"additional","affiliation":[{"name":"Health Behavior and Health Education, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Dubowitz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2008,4,1]]},"reference":[{"key":"2021120902135694900_R1","unstructured":"Administration for Children, Youth, and Families. 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The relationship between childhood maltreatment and adolescent involvement in delinquency. Criminology.\u20081995;33(4):451\u2013481","DOI":"10.1111\/j.1745-9125.1995.tb01186.x"},{"key":"2021120902135694900_R6","doi-asserted-by":"crossref","unstructured":"Zingraff M, Leiter J, Myers K, Johnson M. Child maltreatment and youthful problem behavior. Criminology.\u20081993;31(2):173\u2013202","DOI":"10.1111\/j.1745-9125.1993.tb01127.x"},{"key":"2021120902135694900_R7","doi-asserted-by":"crossref","unstructured":"Hussey JM, Chang JJ, Kotch JB. Child maltreatment in the United States: prevalence, risk factors, and adolescent health consequences. Pediatrics.\u20082006;118(3):933\u2013942","DOI":"10.1542\/peds.2005-2452"},{"key":"2021120902135694900_R8","doi-asserted-by":"crossref","unstructured":"Knutson JF, DeGarmo DS, Reid JB. Social disadvantage and neglectful parenting as precursors to the development of antisocial and aggressive child behavior: testing a theoretical model. 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Int J Offend Ther Comp Criminol.\u20082000;44(2):178\u2013193","DOI":"10.1177\/0306624X00442004"},{"key":"2021120902135694900_R12","doi-asserted-by":"crossref","unstructured":"Kotch JB, Browne DC, Ringwalt CL, et al. Risk of child abuse or neglect in cohort low-income children. Child Abuse Negl.\u20081995;19(9):1115\u20131130","DOI":"10.1016\/0145-2134(95)00072-G"},{"key":"2021120902135694900_R13","doi-asserted-by":"crossref","unstructured":"Kotch JB, Browne DC, Dufort V, Winsor J, Catellier D. Predicting child maltreatment in the first 4 years of life from characteristics assessed in the neonatal period. Child Abuse Negl.\u20081999;23(4):305\u2013319","DOI":"10.1016\/S0145-2134(99)00003-4"},{"key":"2021120902135694900_R14","doi-asserted-by":"crossref","unstructured":"Coulton CJ, Korbin J, Su M, Chow J. Community level factors and child maltreatment rates. 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Substantiated and unsubstantiated cases of child maltreatment: Do their consequences differ?Soc Work Res.\u20081994;18(2):67\u201382","DOI":"10.1093\/swr\/18.2.67"},{"key":"2021120902135694900_R25","unstructured":"Achenbach TM. Manual for the Child Behavior Checklist\/4\u201318 and 1991 Profile. 2nd ed. Burlington, VT: LEA Associates; 1991"},{"key":"2021120902135694900_R26","doi-asserted-by":"crossref","unstructured":"Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. J Appl Psychol Measure.\u20081977;1(3):385\u2013401","DOI":"10.1177\/014662167700100306"},{"key":"2021120902135694900_R27","doi-asserted-by":"crossref","unstructured":"Derogatis LR. Brief Symptom Inventory. Baltimore, MD: Clinical Psychometric Research; 1975","DOI":"10.1037\/t48311-000"},{"key":"2021120902135694900_R28","unstructured":"Hunter WM, Cox CE, Teagle S, et al. Measures for Assessment of Functioning and Outcomes in Longitudinal Research on Child Abuse, Vol 1: Early Childhood. Chapel Hill, NC: University of North Carolina at Chapel Hill; 2003. Available at: www.iprc.unc.edu\/longscan\/pages\/measures\/index.htm. Accessed February 5, 2008"},{"key":"2021120902135694900_R29","unstructured":"Hunter WM, Cox CE, Teagle S, et al. Measures for Assessment of Functioning and Outcomes in Longitudinal Research on Child Abuse, Vol 2: Middle Childhood. Chapel Hill, NC: University of North Carolina at Chapel Hill; 2003. Available at: www.iprc.unc.edu\/longscan\/pages\/measures\/index.htm. Accessed February 5, 2008"},{"key":"2021120902135694900_R30","unstructured":"Chase-Lansdale PL, Gordon RA, Brooks-Gunn J, Klebanov PK. Neighborhood and family influences on the intellectual and behavioral competence of preschool and early school-age children. In: Brooks-Gunn J, Duncan J, Aber JL, eds. Neighborhood Poverty: Context and Consequences for Children. 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Applied Longitudinal Data Analysis: Modeling Change and Even Occurrence. New York, NY: Oxford University Press; 2003","DOI":"10.1093\/acprof:oso\/9780195152968.001.0001"},{"key":"2021120902135694900_R35","doi-asserted-by":"crossref","unstructured":"Dubowitz H. Neglecting the neglect of neglect. J Interpers Violence.\u20081994;9(4):556\u2013560","DOI":"10.1177\/088626094009004010"},{"key":"2021120902135694900_R36","doi-asserted-by":"crossref","unstructured":"Dubowitz H, Papas MA, Black MM, Starr RH Jr. Child neglect: outcomes in high-risk urban preschoolers. Pediatrics.\u20082002;109(6):1100\u20131107","DOI":"10.1542\/peds.109.6.1100"},{"key":"2021120902135694900_R37","doi-asserted-by":"crossref","unstructured":"Bank L, Burraston B. Abusive home environments as predictors of poor adjustment during adolescence and early adulthood. J Community Psychol.\u20082001;29(3):195\u2013217","DOI":"10.1002\/jcop.1014"},{"key":"2021120902135694900_R38","doi-asserted-by":"crossref","unstructured":"Bolger KE, Patterson CJ. Developmental pathways from child maltreatment to peer rejection. Child Dev.\u20082001;72(2):549\u2013568","DOI":"10.1111\/1467-8624.00296"},{"key":"2021120902135694900_R39","doi-asserted-by":"crossref","unstructured":"Widom CS. Child abuse, neglect, and violent criminal behavior. Criminology.\u20081989;27(2):251\u2013271","DOI":"10.1111\/j.1745-9125.1989.tb01032.x"},{"key":"2021120902135694900_R40","doi-asserted-by":"crossref","unstructured":"Youngstrom E, Loeber R, Stouthamer-Loeber M. Patterns and correlates of agreement between parent, teacher, and male adolescent ratings of externalizing and internalizing problems. J Consult Clin Psychol.\u20082000;68(6):1038\u20131050","DOI":"10.1037\/0022-006X.68.6.1038"},{"key":"2021120902135694900_R41","doi-asserted-by":"crossref","unstructured":"Berg-Nielsen TS, Vika A, Dahl AA. When adolescents disagree with their mothers: CBCL-YSR discrepancies related to maternal depression and adolescent self-esteem. Child Care Health Dev.\u20082003;29(3):207\u2013213","DOI":"10.1046\/j.1365-2214.2003.00332.x"},{"key":"2021120902135694900_R42","unstructured":"Office of the Surgeon General. Youth Violence: A Report of the Surgeon General. Rockville, MD: US Department of Health and Human Services; 2001"},{"key":"2021120902135694900_R43","doi-asserted-by":"crossref","unstructured":"Broidy LM, Nagin DS, Tremblay RE, et al. Developmental trajectories of childhood disruptive behaviors and adolescent delinquency: a six-site, cross-national study. 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