{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:38:45Z","timestamp":1790894325660,"version":"4.1.0"},"reference-count":26,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,2,1]]},"abstract":"<jats:p>OBJECTIVE. The objective of this study was to compare the predictive value of qualitative MRI of brain structure at term and general movements assessments at 1 and 3 months' corrected age for motor outcome at 1 year's corrected age in very preterm infants.<\/jats:p>\n               <jats:p>PATIENTS AND METHODS. Eighty-six very preterm infants (&amp;lt;30 weeks' gestation) underwent MRI at term-equivalent age, were evaluated for white matter abnormality, and had general movements assessed at 1 and 3 months' corrected age. Motor outcome at 1 year's corrected age was evaluated with the Alberta Infant Motor Scale, the Neuro-Sensory Motor Development Assessment, and the diagnosis of cerebral palsy by the child's pediatrician.<\/jats:p>\n               <jats:p>RESULTS. At 1 year of age, the Alberta Infant Motor Scale categorized 30 (35%) infants as suspicious\/abnormal; the Neuro-Sensory Motor Development Assessment categorized 16 (18%) infants with mild-to-severe motor dysfunction, and 5 (6%) infants were classified with cerebral palsy. White matter abnormality at term and general movements at 1 and 3 months significantly correlated with Alberta Infant Motor Scale and Neuro-Sensory Motor Development Assessment scores at 1 year. White matter abnormality and general movements at 3 months were the only assessments that correlated with cerebral palsy. All assessments had 100% sensitivity in predicting cerebral palsy. White matter abnormality demonstrated the greatest accuracy in predicting combined motor outcomes, with excellent levels of specificity (&amp;gt;90%); however, the sensitivity was low. On the other hand, general movements assessments at 1 month had the highest sensitivity (&amp;gt;80%); however, the overall accuracy was relatively low.<\/jats:p>\n               <jats:p>CONCLUSION. Neuroimaging (MRI) and functional (general movements) examinations have important complementary roles in predicting motor development of very preterm infants.<\/jats:p>","DOI":"10.1542\/peds.2008-0590","type":"journal-article","created":{"date-parts":[[2009,1,26]],"date-time":"2009-01-26T12:23:44Z","timestamp":1232972624000},"page":"512-517","source":"Crossref","is-referenced-by-count":156,"title":["Predicting Motor Development in Very Preterm Infants at 12 Months\u2019 Corrected Age: The Role of Qualitative Magnetic Resonance Imaging and General Movements Assessments"],"prefix":"10.1542","volume":"123","author":[{"given":"Alicia J.","family":"Spittle","sequence":"first","affiliation":[{"name":"Victorian Infant Brain Studies, Murdoch Childrens Research Institute, Melbourne, Australia"},{"name":"School of Physiotherapy, Departments of"},{"name":"Pediatrics"},{"name":"Royal Women's Hospital, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roslyn N.","family":"Boyd","sequence":"additional","affiliation":[{"name":"Pediatrics"},{"name":"Queensland Cerebral and Rehabilitation Research Center, University of Queensland, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terrie E.","family":"Inder","sequence":"additional","affiliation":[{"name":"Victorian Infant Brain Studies, Murdoch Childrens Research Institute, Melbourne, Australia"},{"name":"Departments of Pediatrics, Neurology and Radiology, St Louis Children's Hospital, Washington University, St Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lex W.","family":"Doyle","sequence":"additional","affiliation":[{"name":"Victorian Infant Brain Studies, Murdoch Childrens Research Institute, Melbourne, Australia"},{"name":"Pediatrics"},{"name":"Royal Women's Hospital, Melbourne, Australia"},{"name":"Obstetrics and Gynecology, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2009,2,1]]},"reference":[{"key":"2021120822541475700_R1","doi-asserted-by":"crossref","unstructured":"Lumley J. 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