{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T17:17:24Z","timestamp":1770571044156,"version":"3.49.0"},"reference-count":40,"publisher":"American Academy of Pediatrics (AAP)","issue":"Supplement_2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,10,1]]},"abstract":"<jats:p>OBJECTIVE. Our goal was to identify the frequency, demographics, and diagnostic characteristics associated with maternally reported food allergies and other food-related health problems among infants aged \u22641 year.<\/jats:p><jats:p>METHODS. We analyzed data from the 2005\u20132007 Infant Feeding Practices Study II, a longitudinal survey of 2441 US mothers of healthy singletons from pregnancy through their infant's first year. Doctor diagnosis and symptoms-based criteria were used to identify a probable-food-allergic group from maternal reports of infant health problems with food.<\/jats:p><jats:p>RESULTS. More than one fifth of the 2441 mothers reported that their infant had a food-related problem; 6% (n = 143) had a probable food allergy, and 15% (n = 359) had other food-related problems. Forty percent of the infants with a food-related health problem were evaluated by a doctor. Gastrointestinal symptoms were more commonly reported in early infancy compared with skin-related symptoms, which were reported in later infancy, and 27% received medical treatment for the symptoms. Characteristics associated with increased incidence of probable food allergy included family histories of food allergy and type 1 diabetes, gestational diabetes, living in rural or urban areas, being black, and being male. Among all infants with a food-related health problem, the majority experienced their first problem by 6 months of age. Foods recognized to be major allergens were most commonly reported as the source of an allergy.<\/jats:p><jats:p>CONCLUSIONS. Food-related problems occurred at a high frequency in the first year of life. A better understanding of the demographics, family history, disease manifestations, and diagnoses may provide insight into public health efforts to minimize or prevent food allergies in infancy and to help differentiate food-allergic problems from nonallergic food problems in this age group.<\/jats:p>","DOI":"10.1542\/peds.2008-1315n","type":"journal-article","created":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T13:24:37Z","timestamp":1222867477000},"page":"S105-S112","source":"Crossref","is-referenced-by-count":38,"title":["Maternally Reported Food Allergies and Other Food-Related Health Problems in Infants: Characteristics and Associated Factors"],"prefix":"10.1542","volume":"122","author":[{"given":"Stefano","family":"Luccioli","sequence":"first","affiliation":[{"name":"Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Ross","sequence":"additional","affiliation":[{"name":"Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Labiner-Wolfe","sequence":"additional","affiliation":[{"name":"Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara B.","family":"Fein","sequence":"additional","affiliation":[{"name":"Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2008,10,1]]},"reference":[{"key":"2021120820435879500_R1","doi-asserted-by":"crossref","unstructured":"Bock SA, Munoz-Furlong A, Sampson HA. Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol.\u20082001;107(1):191\u2013193","DOI":"10.1067\/mai.2001.112031"},{"key":"2021120820435879500_R2","doi-asserted-by":"crossref","unstructured":"Sampson HA. Anaphylaxis and emergency treatment. Pediatrics.\u20082003;111(6 pt 3):1601\u20131608","DOI":"10.1542\/peds.111.S3.1601"},{"key":"2021120820435879500_R3","doi-asserted-by":"crossref","unstructured":"Grundy J, Matthews S, Bateman B, Dean T, Arshad SH. Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts. J Allergy Clin Immunol.\u20082002;110(5):784\u2013789","DOI":"10.1067\/mai.2002.128802"},{"key":"2021120820435879500_R4","doi-asserted-by":"crossref","unstructured":"Sicherer SH, Munoz-Furlong A, Sampson HA. Prevalence of peanut and tree nut allergy in the United States determined by means of a random digit dial telephone survey: a 5-year follow-up study. J Allergy Clin Immunol.\u20082003;112(6):1203\u20131207","DOI":"10.1016\/S0091-6749(03)02026-8"},{"key":"2021120820435879500_R5","doi-asserted-by":"crossref","unstructured":"Sampson HA. Update on food allergy. J Allergy Clin Immunol.\u20082004;113(5):805\u2013819","DOI":"10.1016\/j.jaci.2004.03.014"},{"key":"2021120820435879500_R6","doi-asserted-by":"crossref","unstructured":"Lee LA, Burks AW. Food allergies: prevalence, molecular characterization, and treatment\/prevention strategies. Annu Rev Nutr.\u20082006;26:539\u2013565","DOI":"10.1146\/annurev.nutr.26.061505.111211"},{"key":"2021120820435879500_R7","doi-asserted-by":"crossref","unstructured":"Wickman M. When allergies complicate allergies. Allergy.\u20082005;60(suppl 79):S14\u2013S18","DOI":"10.1111\/j.1398-9995.2005.00852.x"},{"key":"2021120820435879500_R8","doi-asserted-by":"crossref","unstructured":"Muraro A, Roberts G, Clark A, et al. The management of anaphylaxis in childhood: position paper of the European Academy of Allergology and Clinical Immunology. Allergy.\u20082007;62(8):857\u2013871","DOI":"10.1111\/j.1398-9995.2007.01421.x"},{"key":"2021120820435879500_R9","doi-asserted-by":"crossref","unstructured":"Sicherer SH, Burks AW, Sampson HA. Clinical features of acute allergic reactions to peanut and tree nuts in children. Pediatrics.\u20081998;102(1). Available at: www.pediatrics.org\/cgi\/content\/full\/102\/1\/e6","DOI":"10.1542\/peds.102.1.e6"},{"key":"2021120820435879500_R10","doi-asserted-by":"crossref","unstructured":"Host A, Andrae S, Charkin S, et al. Allergy testing in children: why, who, when and how?Allergy.\u20082003;58(7):559\u2013569","DOI":"10.1034\/j.1398-9995.2003.00238.x"},{"key":"2021120820435879500_R11","doi-asserted-by":"crossref","unstructured":"Bock SA. Prospective appraisal of complaints of adverse reactions to foods in children during the first 3 years of life. Pediatrics.\u20081987;79(5):683\u2013688","DOI":"10.1542\/peds.79.5.683"},{"key":"2021120820435879500_R12","doi-asserted-by":"crossref","unstructured":"Kajosaari M. Food allergy in Finnish children aged 1 to 6 years. Acta Paediatr Scand.\u20081982;71(5):815\u2013819","DOI":"10.1111\/j.1651-2227.1982.tb09525.x"},{"key":"2021120820435879500_R13","doi-asserted-by":"crossref","unstructured":"Eggesbo M, Halvorsen R, Tambs K, Botten G. Prevalence of parentally perceived adverse reactions to food in young children. Pediatr Allergy Immunol.\u20081999;10(2):122\u2013132","DOI":"10.1034\/j.1399-3038.1999.00022.x"},{"key":"2021120820435879500_R14","doi-asserted-by":"crossref","unstructured":"Kristjansson I, Ardal B, Jonsson JS, Sigurdsson JA, Foldevi M, Bjo\u0308rkste\u0301n B. Adverse reactions to food and food allergy in young children in Iceland and Sweden. Scand J Prim Health Care.\u20081999;17(1):30\u201334","DOI":"10.1080\/028134399750002863"},{"key":"2021120820435879500_R15","doi-asserted-by":"crossref","unstructured":"Venter C, Pereira B, Grundy J, et al. Incidence of parentally reported and clinically diagnosed food hypersensitivity in the first year of life. J Allergy Clin Immunol.\u20082006;117(5):1118\u20131124","DOI":"10.1016\/j.jaci.2005.12.1352"},{"key":"2021120820435879500_R16","doi-asserted-by":"crossref","unstructured":"Osterballe M, Hansen TK, Mortz CG, Host A, Bindslev-Jensen C. The prevalence of food hypersensitivity in an unselected population of children and adults. Pediatr Allergy Immunol.\u20082005;16(7):567\u2013573","DOI":"10.1111\/j.1399-3038.2005.00251.x"},{"key":"2021120820435879500_R17","doi-asserted-by":"crossref","unstructured":"Sicherer SH. Clinical aspects of gastrointestinal food allergy in childhood. Pediatrics.\u20082003;111(6 pt 3):1609\u20131616","DOI":"10.1542\/peds.111.S3.1609"},{"key":"2021120820435879500_R18","doi-asserted-by":"crossref","unstructured":"Fein SB, Labiner-Wolfe J, Shealy KR, Li R, Chen J, Grummer-Strawn LM. Infant Feeding Practices Study II: study methods. Pediatrics.\u20082008;122(suppl 2):S28\u2013S35","DOI":"10.1542\/peds.2008-1315c"},{"key":"2021120820435879500_R19","doi-asserted-by":"crossref","unstructured":"Sampson HA. Food allergy. Part 1: immunopathogenesis and clinical disorders. J Allergy Clin Immunol.\u20081999;103(5 pt 1):717\u2013728","DOI":"10.1016\/S0091-6749(99)70411-2"},{"key":"2021120820435879500_R20","doi-asserted-by":"crossref","unstructured":"Sicherer SH. Determinants of systemic manifestations of food allergy. J Allergy Clin Immunol.\u20082000;106(5 suppl):S251\u2013S257","DOI":"10.1067\/mai.2000.110158"},{"key":"2021120820435879500_R21","doi-asserted-by":"crossref","unstructured":"Burks W. Skin manifestations of food allergy. Pediatrics.\u20082003;111(6 pt 3):1617\u20131624","DOI":"10.1542\/peds.111.S3.1617"},{"key":"2021120820435879500_R22","doi-asserted-by":"crossref","unstructured":"Wu\u0308thrich B. Food-induced cutaneous adverse reactions. Allergy.\u20081998;53(46 suppl):131\u2013135","DOI":"10.1111\/j.1398-9995.1998.tb04983.x"},{"key":"2021120820435879500_R23","doi-asserted-by":"crossref","unstructured":"Wood RA. The natural history of food allergy. Pediatrics.\u20082003;111(6 pt 3):1631\u20131637","DOI":"10.1542\/peds.111.S3.1631"},{"key":"2021120820435879500_R24","doi-asserted-by":"crossref","unstructured":"Rona RJ, Keil T, Summers C, et al. The prevalence of food allergy: a meta-analysis. J Allergy Clin Immunol.\u20082007;120(3):638\u2013646","DOI":"10.1016\/j.jaci.2007.05.026"},{"key":"2021120820435879500_R25","unstructured":"Wilson NW, Hamburger RN. Allergy to cow's milk in the first year of life and its prevention. Ann Allergy.\u20081988;61(5):323\u2013327"},{"key":"2021120820435879500_R26","doi-asserted-by":"crossref","unstructured":"Zeiger RS, Sampson HA, Bock SA, et al. Soy allergy in infants and children with IgE-associated cow's milk allergy. J Pediatr.\u20081999;134(5):614\u2013622","DOI":"10.1016\/S0022-3476(99)70249-0"},{"key":"2021120820435879500_R27","unstructured":"Santadusit S, Atthapaisalsarudee S, Vichyanond P. Prevalence of adverse food reactions and food allergy among Thai children. J Med Assoc Thai.\u20082005;88(suppl 8):S27\u2013S32"},{"key":"2021120820435879500_R28","doi-asserted-by":"crossref","unstructured":"Zeiger RS. Food allergen avoidance in the prevention of food allergy in infants and children. Pediatrics.\u20082003;111(6 pt 3):1662\u20131671","DOI":"10.1542\/peds.111.S3.1662"},{"key":"2021120820435879500_R29","doi-asserted-by":"crossref","unstructured":"Kjellman NI. Atopic disease in seven-year-old children: incidence in relation to family history. Acta Paediatr Scand.\u20081977;66(4):465\u2013471","DOI":"10.1111\/j.1651-2227.1977.tb07928.x"},{"key":"2021120820435879500_R30","doi-asserted-by":"crossref","unstructured":"Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med.\u20081995;332(3):133\u2013138","DOI":"10.1056\/NEJM199501193320301"},{"key":"2021120820435879500_R31","doi-asserted-by":"crossref","unstructured":"Arshad SH, Kurukulaaratchy RJ, Fenn M, Matthews S. Early life risk factors for current wheeze, asthma, and bronchial hyperresponsiveness at 10 years of age. Chest.\u20082005;127(2):502\u2013508","DOI":"10.1378\/chest.127.2.502"},{"key":"2021120820435879500_R32","doi-asserted-by":"crossref","unstructured":"Mo\u0308hrenschlager M, Schafer T, Huss-Marp J, et al. The course of eczema in children aged 5\u20137 years and its relation to atopy: differences between boys and girls. Br J Dermatol.\u20082006;154(3):505\u2013513","DOI":"10.1111\/j.1365-2133.2005.07042.x"},{"key":"2021120820435879500_R33","doi-asserted-by":"crossref","unstructured":"Lowe AJ, Carlin JB, Bennett CM, et al. Do boys do the atopic march while girls dawdle?J Allergy Clin Immunol.\u20082008;121(5):1190\u20131195","DOI":"10.1016\/j.jaci.2008.01.034"},{"key":"2021120820435879500_R34","doi-asserted-by":"crossref","unstructured":"Nilsson L, Kivling A, Jalmelid M, Magnusson KF, Faresjo M. Combinations of common chronic paediatric diseases deviate the immune response in diverging directions. Clin Exp Immunol.\u20082006;146(3):433\u2013442","DOI":"10.1111\/j.1365-2249.2006.03228.x"},{"key":"2021120820435879500_R35","doi-asserted-by":"crossref","unstructured":"Stene LC, Joner G. Atopic disorders and risk of childhood-onset type 1 diabetes in individuals. Clin Exp Allergy.\u20082004;34(2):201\u2013206","DOI":"10.1111\/j.1365-2222.2004.01864.x"},{"key":"2021120820435879500_R36","doi-asserted-by":"crossref","unstructured":"Caffarelli C, Cavagni G, Pierdomenico R, Chiari G, Spattini A, Vanelli M. Coexistence of IgE-mediated allergy and type 1 diabetes in childhood. Int Arch Allergy Immunol.\u20082004;134(4):288\u2013294","DOI":"10.1159\/000079166"},{"key":"2021120820435879500_R37","doi-asserted-by":"crossref","unstructured":"von Mutius E. Allergies, infections and the hygiene hypothesis: the epidemiological evidence. Immunobiology.\u20082007;212(6):433\u2013439","DOI":"10.1016\/j.imbio.2007.03.002"},{"key":"2021120820435879500_R38","doi-asserted-by":"crossref","unstructured":"Carvalho NF, Kenney RD, Carrington PH, Hall DE. Severe nutritional deficiencies in toddlers resulting from health food milk alternatives. Pediatrics.\u20082001;107(4). Available at: www.pediatrics.org\/cgi\/content\/full\/107\/4\/e46","DOI":"10.1542\/peds.107.4.e46"},{"key":"2021120820435879500_R39","doi-asserted-by":"crossref","unstructured":"Lightdale JR, Oken E. Breastfeeding, food choices, restrictive diets, and nutritional fads. Curr Opin Pediatr.\u20082002;14(3):344\u2013349","DOI":"10.1097\/00008480-200206000-00013"},{"key":"2021120820435879500_R40","doi-asserted-by":"crossref","unstructured":"Sicherer SH, Noone SA, Munoz-Furlong A. The impact of childhood food allergy on quality of life. Ann Allergy Asthma Immunol.\u20082001;87(6):461\u2013464","DOI":"10.1016\/S1081-1206(10)62258-2"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/122\/Supplement_2\/S105\/891324\/zpe1100800s105.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/122\/Supplement_2\/S105\/891324\/zpe1100800s105.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T06:01:51Z","timestamp":1684562511000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/122\/Supplement_2\/S105\/29432\/Maternally-Reported-Food-Allergies-and-Other-Food"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,1]]},"references-count":40,"journal-issue":{"issue":"Supplement_2","published-online":{"date-parts":[[2008,10,1]]},"published-print":{"date-parts":[[2008,10,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2008-1315n","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,1]]}}}