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The aims of the Auditory\/Hearing Late Effects Task Force of the Children's Oncology Group in this report were to (1) review ototoxicity resulting from childhood cancer therapy including platinum compounds (cisplatin and carboplatin) and radiation, (2) describe briefly cochlear pathophysiology and genetics of cisplatin-related hearing loss, (3) explain the impact of hearing loss resulting from chemotherapy and radiation, and (4) offer recommendations regarding evaluation and management of pediatric patients who are at risk for treatment-related hearing loss. A questionnaire is included as a tool to assist pediatricians in assessment.<\/jats:p>","DOI":"10.1542\/peds.2009-1597","type":"journal-article","created":{"date-parts":[[2010,3,2]],"date-time":"2010-03-02T03:23:00Z","timestamp":1267500180000},"page":"e938-e950","source":"Crossref","is-referenced-by-count":176,"title":["Auditory Late Effects of Childhood Cancer Therapy: A Report From the Children's Oncology Group"],"prefix":"10.1542","volume":"125","author":[{"given":"Satkiran","family":"Grewal","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatrics, Baystate Medical Center, Springfield, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Merchant","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, St Jude Children's Research Hospital, University of Tennessee College of Medicine, Memphis, 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