{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:21:53Z","timestamp":1793053313905,"version":"4.5.0"},"reference-count":16,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,6,1]]},"abstract":"<jats:p>Recognition of Crohn disease in children who present with cutaneous vulvar lesions as their initial clinical manifestation is often difficult. We report here the case of an 8-year-old girl with chronic vulvar edema, which on biopsy revealed granulomatous inflammation of the vulva. Further investigation and biopsy of the terminal ileum demonstrated similar findings and was consistent with a diagnosis of Crohn disease.<\/jats:p>","DOI":"10.1542\/peds.2009-1829","type":"journal-article","created":{"date-parts":[[2010,5,11]],"date-time":"2010-05-11T03:09:14Z","timestamp":1273547354000},"page":"e1518-e1522","source":"Crossref","is-referenced-by-count":24,"title":["Vulvar Inflammation as the Only Clinical Manifestation of Crohn Disease in an 8-Year-Old Girl"],"prefix":"10.1542","volume":"125","author":[{"given":"Shannon L.","family":"Corbett","sequence":"first","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catharine M.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel F.","family":"Spitzer","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo-Yee","family":"Ngan","sequence":"additional","affiliation":[{"name":"Pathology, Hospital for Sick Children, Toronto, Ontario"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari","family":"Kives","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Zachos","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2010,6,1]]},"reference":[{"issue":"6","key":"2021120905321908300_B1","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0190-9622(81)70130-0","article-title":"Cutaneous manifestations of Crohn's disease","volume":"5","author":"Burgdorf","year":"1981","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"2021120905321908300_B2","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1525-1470.2006.00170.x","article-title":"Cutaneous Crohn disease in a child","volume":"23","author":"Pinna","year":"2006","journal-title":"Pediatr Dermatol"},{"issue":"5 pt 1","key":"2021120905321908300_B3","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0190-9622(97)80320-9","article-title":"Cutaneous Crohn's disease in children","volume":"36","author":"Ploysangam","year":"1997","journal-title":"J Am Acad Dermatol"},{"issue":"5","key":"2021120905321908300_B4","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/j.1365-2133.1976.tb00868.x","article-title":"Metastatic Crohn's disease","volume":"95","author":"McCallum","year":"1976","journal-title":"Br J Dermatol"},{"issue":"5 pt 2","key":"2021120905321908300_B5","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/0190-9622(92)70276-L","article-title":"Crohn's disease presenting as unilateral labial hypertrophy","volume":"27","author":"Werlin","year":"1992","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"2021120905321908300_B6","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/00005176-199508000-00005","article-title":"Highly destructive perianal disease in children with Crohn's disease","volume":"21","author":"Markowitz","year":"1995","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"10","key":"2021120905321908300_B7","first-page":"1725","article-title":"Gynecologic aspects of Crohn's disease","volume":"64","author":"Feller","year":"2001","journal-title":"Am Fam Physician"},{"key":"2021120905321908300_B8","first-page":"241","article-title":"Crohn's disease with cutaneous involvement","volume":"58","author":"Parks","year":"1965","journal-title":"Proc R Soc Med"},{"issue":"9","key":"2021120905321908300_B9","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1468-3083.2008.02741.x","article-title":"Metastatic Crohn's disease: a review","volume":"22","author":"Palamaras","year":"2008","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"2","key":"2021120905321908300_B10","first-page":"197","article-title":"Crohn's disease of the vulva in a 10-year-old girl","volume":"50","author":"Kulo\u011flu","year":"2008","journal-title":"Turk J Pediatr"},{"issue":"3","key":"2021120905321908300_B11","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jpag.2006.02.009","article-title":"What's your diagnosis? 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