{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:43:20Z","timestamp":1784195000437,"version":"3.55.0"},"reference-count":23,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVES:<\/jats:title>\n                  <jats:p>To describe the duration of illness in infants with first-time bronchiolitis who present to an emergency department (ED) and assess the burden of the illness on caregivers and families.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>This was a prospective cohort study of infants younger than 12 months who presented to a tertiary care children's hospital ED with a first episode of bronchiolitis. Subjects were excluded if they had a history of bronchodilator use or immunocompromise. Demographic and clinical data were collected in the ED. Outcomes data were collected by weekly telephone interviews for 4 weeks or until the subject was free of cough for 24 hours.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>Ninety-five infants were enrolled from November 2007 to March 2008. Median duration of symptoms was 15 days; 25% of the infants remained symptomatic after 21 days. Subjects with a history of eczema trended toward a longer median duration of symptoms when compared with those who did not (18 days [interquartile range (IQR): 15.5\u201324] and 15 days [IQR: 11\u201319], respectively; P = .055). Duration of symptoms did not significantly vary with regards to respiratory syncytial virus status or secondhand smoke exposure. Subjects missed a median of 2.5 days (IQR: 0.5\u20135.5) of day care, and caregivers missed a median of 2 days (IQR: 1\u20134) of work. Of these infants, 37.1% (95% confidence interval: 24.3\u201344.1) had a subsequent unscheduled medical visit.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Infants seen in the ED for bronchiolitis have a prolonged disease course, with substantial burden to the family. Symptom duration may be influenced by a propensity toward atopy. Clinicians may use this information for counseling families.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2009-2189","type":"journal-article","created":{"date-parts":[[2010,7,13]],"date-time":"2010-07-13T00:59:43Z","timestamp":1278982783000},"page":"285-290","source":"Crossref","is-referenced-by-count":30,"title":["Duration of Illness in Infants With Bronchiolitis Evaluated in the Emergency Department"],"prefix":"10.1542","volume":"126","author":[{"given":"Frank D.","family":"Petruzella","sequence":"first","affiliation":[{"name":"Division of Emergency Medicine, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc H.","family":"Gorelick","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, 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