{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:42:05Z","timestamp":1790617325916,"version":"4.1.0"},"reference-count":36,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,5,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE:<\/jats:title>\n                  <jats:p>This study compared the prevalence of symptoms of posttraumatic stress disorder (PTSD), with functional impairment and\/or clinical distress, among very long-term survivors of childhood cancer and a group of healthy siblings.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>A total of 6542 childhood cancer survivors &amp;gt;18 years of age who received diagnoses between 1970 and 1986 and 368 siblings of cancer survivors completed a comprehensive demographic and health survey.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>A total of 589 survivors (9%) and 8 siblings (2%) reported functional impairment and\/or clinical distress in addition to the set of symptoms consistent with a full diagnosis of PTSD. Survivors had more than fourfold greater risk of PTSD, compared with siblings (odds ratio [OR]: 4.14 [95% confidence interval [CI]: 2.08\u20138.25]). With controlling for demographic and treatment variables, increased risk of PTSD was associated with educational level of high school or less (OR: 1.51 [95% CI: 1.16\u20131.98]), being unmarried (OR: 1.99 [95% CI: 1.58\u20132.50]), having annual income below $20000 (OR: 1.63 [95% CI: 1.21\u20132.20]), and being unemployed (OR: 2.01 [95% CI: 1.62\u20132.51]). Intensive treatment also was associated with increased risk of full PTSD (OR: 1.36 [95% CI: 1.06\u20131.74]).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>PTSD was reported significantly more often by survivors of childhood cancer than by sibling control subjects. Although most survivors apparently are faring well, a subset reported significant impairment that may warrant targeted intervention.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2009-2308","type":"journal-article","created":{"date-parts":[[2010,4,30]],"date-time":"2010-04-30T15:48:35Z","timestamp":1272642515000},"page":"e1124-e1134","source":"Crossref","is-referenced-by-count":163,"title":["Prevalence and Predictors of Posttraumatic Stress Disorder in Adult Survivors of Childhood Cancer"],"prefix":"10.1542","volume":"125","author":[{"given":"Margaret L.","family":"Stuber","sequence":"first","affiliation":[{"name":"Departments of Psychiatry,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Meeske","sequence":"additional","affiliation":[{"name":"Children's Center for Cancer and Blood Diseases, Children's Hospital of Los Angeles, Los Angeles, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin 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