{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:42:32Z","timestamp":1790437352845,"version":"4.1.0"},"reference-count":14,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,1,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE:<\/jats:title>\n                  <jats:p>To describe in detail the pediatric intensive care experience of influenza A, particularly pandemic H1N1-09, in Australia and New Zealand during the 2009 Southern Hemisphere winter and to compare the pediatric experience with that of adults.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHOD:<\/jats:title>\n                  <jats:p>This was an inception-cohort study of all children who were admitted to intensive care with confirmed influenza A during winter 2009 at all general ICUs and PICUs in Australia and New Zealand.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>From June 1 through August 31, 2009, 107 children (20.0 per million [95% confidence interval: 16.1\u201323.8]) with influenza A, including 83 (15.5 per million [95% confidence interval: 12.1\u201318.9]) with H1N1-09 were admitted to ICUs. Fifty-two percent (39 of 75) of children with H1N1-09 had 1 or more comorbidity, most commonly neurologic (20%). Most (48 of 83 [58%]) presented with pneumonia. Thirteen of 83 (16%) had neurologic presentations. Eighty percent of the children with H1N1-09 required ventilation. Mortality was lower than in adults: 6 of 83 (7%) vs 114 of 668 (17%) (P = .02). The median length of stay for children with H1N1-09 was 5 days. Children with H1N1-09 occupied 773 bed-days (147 per million children) and 5.8% of specialist PICU beds. Presentation with septic shock or after cardiac arrest and the presence of 1 or more comorbidities were risk factors for severe disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>H1N1-09 caused a substantial burden on pediatric intensive care services in Australia and New Zealand. Compared with adults, children more commonly had nonrespiratory presentations and required ventilation more often but had a lower mortality rate.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2010-0801","type":"journal-article","created":{"date-parts":[[2010,12,21]],"date-time":"2010-12-21T05:18:43Z","timestamp":1292908723000},"page":"e156-e163","source":"Crossref","is-referenced-by-count":24,"title":["Pandemic H1N1 in Children Requiring Intensive Care in Australia and New Zealand During Winter 2009"],"prefix":"10.1542","volume":"127","author":[{"given":"Michael","family":"Yung","sequence":"first","affiliation":[{"name":"Intensive Care Unit, Women's and Children's Hospital, Adelaide, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Slater","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Royal Children's Hospital, Brisbane, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marino","family":"Festa","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Children's Hospital at Westmead, Sydney, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Williams","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Sydney Children's Hospital, Sydney, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Erickson","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Princess Margaret Hospital, Perth, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ville","family":"Pettila","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia;"},{"name":"Intensive Care Unit, Helsinki University Hospital, Helsinki, Finland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet","family":"Alexander","sequence":"additional","affiliation":[{"name":"Australia and New Zealand Paediatric Intensive Care Registry, Brisbane, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belinda D.","family":"Howe","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia;"},{"name":"Australia and New Zealand Intensive Care Research Centre, Melbourne, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara S.","family":"Shekerdemian","sequence":"additional","affiliation":[{"name":"Paediatric Intensive Care, Royal Children's Hospital, Melbourne, Australia;"},{"name":"Department of pediatrics, Murdoch Children's Research Institute, Melbourne Australia; and"},{"name":"Department of Pediatrics, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Australia and New Zealand Intensive Care Influenza Investigators and the Paediatric Study Group and the Clinical Trials Group of the Australia New Zealand Intensive Care Society","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2011,1,1]]},"reference":[{"key":"2021120900233529000_B1","unstructured":"World Health Organization. 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Available at: www.abs.gov.au\/Ausstats\/abs@.nsf\/mf\/3201.0. Accessed November 19, 2009"},{"key":"2021120900233529000_B7","unstructured":"Statistics New Zealand. Estimated national ethnic population by age and sex at 30 June 1996, 2001 and 2006. 2006. Available at: http:\/\/wdmzpub01.stats.govt.nz\/wds\/tableviewer\/dimview.aspx. Accessed November 19, 2009"},{"key":"2021120900233529000_B8","unstructured":"Australian Bureau of Statistics. Indigenous status by age\u2014Australia. 2008. Available at: www.censusdata.abs.gov.au\/ABSNavigation\/ prenav\/ViewData?method=Place%20of% 20Usual%20Residence&subaction=\u22121& producttype=Census%20Tables&areacode= 0&order=1&productlabel=Indigenous% 20Status%20by%20Age&tabname=Details& action=404&documenttype=Details& collection=Census&textversion=false& breadcrumb=TLPD&period=2006&issue= 2006&javascript=true&navmapdisplayed= true&documentproductno=0&. 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