{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T03:02:24Z","timestamp":1761966144178,"version":"build-2065373602"},"reference-count":34,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,11,1]]},"abstract":"<jats:p>Guidelines for the treatment of Lyme arthritis were published by the Infectious Diseases Society of America in 2006 and recommended oral doxycycline for initial therapy. We report here the case of a young girl treated with intravenous ceftriaxone who subsequently developed drug-induced autoimmune hemolytic anemia and renal failure. Her severe sequelae highlight the importance of antimicrobial stewardship. We review here the goals of antimicrobial stewardship and several strategies for achieving them. In addition, we briefly discuss the rare adverse drug event experienced by our patient.<\/jats:p>","DOI":"10.1542\/peds.2010-1570","type":"journal-article","created":{"date-parts":[[2011,10,4]],"date-time":"2011-10-04T00:25:53Z","timestamp":1317687953000},"page":"e1289-e1292","source":"Crossref","is-referenced-by-count":15,"title":["Ceftriaxone-Induced Hemolysis in a Child With Lyme Arthritis: A Case for Antimicrobial Stewardship"],"prefix":"10.1542","volume":"128","author":[{"given":"Sarah R.","family":"Boggs","sequence":"first","affiliation":[{"name":"Children's Hospital of The King's Daughters and Eastern Virginia Medical School, Norfolk, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji M.","family":"Cunnion","sequence":"additional","affiliation":[{"name":"Children's Hospital of The King's Daughters and Eastern Virginia Medical School, Norfolk, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem H.","family":"Raafat","sequence":"additional","affiliation":[{"name":"Children's Hospital of The King's Daughters and Eastern Virginia Medical School, Norfolk, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2011,11,1]]},"reference":[{"issue":"11","key":"2021120900354227400_B1","first-page":"1","article-title":"CDC officials want physicians to \u201cget smart\u201d about antibiotic use","volume":"23","author":"Foster","year":"2010","journal-title":"Infect Dis Child"},{"issue":"2","key":"2021120900354227400_B2","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1086\/510393","article-title":"Society for Healthcare Epidemiology of America Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship","volume":"44","author":"Dellit","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"9","key":"2021120900354227400_B3","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1086\/508667","article-title":"The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America [published correction appears in Clin Infect Dis. 2007;45(7):941]","volume":"43","author":"Wormser","year":"2006","journal-title":"Clin Infect Dis"},{"issue":"5","key":"2021120900354227400_B4","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.3899\/jrheum.090711","article-title":"Outcomes of children treated for Lyme arthritis: results of a large pediatric cohort","volume":"37","author":"Tory","year":"2010","journal-title":"J Rheumatol"},{"issue":"5","key":"2021120900354227400_B5","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1097\/INF.0b013e3181c94d9e","article-title":"Infectious complications of peripherally inserted central venous catheters in children","volume":"29","author":"Levy","year":"2010","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"2021120900354227400_B6","doi-asserted-by":"crossref","DOI":"10.1542\/peds.107.2.e28","article-title":"Pediatric peripherally inserted central catheters: complication rates related to catheter tip location","volume":"107","author":"Racadio","year":"2001","journal-title":"Pediatrics"},{"issue":"2","key":"2021120900354227400_B7","doi-asserted-by":"crossref","DOI":"10.1542\/peds.99.2.e4","article-title":"Survey of the use of peripherally inserted central venous catheters in children","volume":"99","author":"Thiagarajan","year":"1997","journal-title":"Pediatrics"},{"issue":"2","key":"2021120900354227400_B8","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1067\/mpd.2003.67","article-title":"Peripherally inserted central catheter (PICC) fracture and embolization in the pediatric population","volume":"142","author":"Chow","year":"2003","journal-title":"J Pediatr"},{"key":"2021120900354227400_B9","unstructured":"Rocephin (ceftriaxone sodium) injection, powder, for solution [Genentech, Inc]. 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