{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T02:07:33Z","timestamp":1784081253607,"version":"3.55.0"},"reference-count":18,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,2,1]]},"abstract":"<jats:sec><jats:title>CONTEXT:<\/jats:title><jats:p>Intussusception is the most common cause of intestinal obstruction in young children, and delayed diagnosis may lead to bowel perforation.<\/jats:p><\/jats:sec><jats:sec><jats:title>OBJECTIVE:<\/jats:title><jats:p>To determine predictive clinical criteria and develop a decision tree to risk-stratify children with possible intussusception.<\/jats:p><\/jats:sec><jats:sec><jats:title>DESIGN\/METHODS:<\/jats:title><jats:p>This is a prospective observational cohort study of children aged 1 month to 6 years who presented with possible intussusception. A data-collection form was completed before knowledge of any advanced imaging. Univariate analysis was performed, and decision trees were developed using recursive partitioning.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>In the study, 310 patients were enrolled, including 38 (12.3%) with intussusception. The median age was 21.1 months and 61% were male. Univariate predictors of intussusception included age older than 6 months (P = 0.04), male gender (P = .007), history of lethargy (P = .001), and abnormal plain x-ray (P = .0001). Multivariate analysis through recursive partitioning identified decision trees (with and without the result of a plain abdominal x-ray) and allowed identification of patients at low risk. The decision tree based on the results of an abdominal x-ray (negative or positive), age (\u2a7d5 or &amp;gt;5 months), diarrhea (present or absent), and bilious emesis (present or absent) had the best test performance (sensitivity: 97% [95% confidence interval (CI): 86\u2013100]; negative predictive value: 99% [95% CI: 93\u2013100]; negative likelihood ratio: 0.08 [95% CI: 0.01\u20130.6]).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Among children who were being evaluated for intussusception, we prospectively determined clinical criteria and developed a decision tree to risk-stratify children with possible intussusception.<\/jats:p><\/jats:sec>","DOI":"10.1542\/peds.2010-2432","type":"journal-article","created":{"date-parts":[[2011,1,18]],"date-time":"2011-01-18T03:03:17Z","timestamp":1295319797000},"page":"e296-e303","source":"Crossref","is-referenced-by-count":44,"title":["Risk Stratification of Children Being Evaluated for Intussusception"],"prefix":"10.1542","volume":"127","author":[{"given":"Sarah N.","family":"Weihmiller","sequence":"first","affiliation":[{"name":"Division of Emergency Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Buonomo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Children's Hospital Boston, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Bachur","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2011,2,1]]},"reference":[{"issue":"5","key":"2021121007091384600_B1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1097\/00005176-200411000-00012","article-title":"Clinical case definition for the diagnosis of acute intussusception","volume":"39","author":"Bines","year":"2004","journal-title":"J Pediatr 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