{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T08:30:13Z","timestamp":1792657813039,"version":"4.5.0"},"reference-count":45,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,6,1]]},"abstract":"<jats:p>Mycoplasma pneumoniae is a highly specialized parasitic bacterium that is a significant cause of community-acquired pneumonia in children. Although most such respiratory infections are mild, a minor percentage of patients require hospitalization and, occasionally, intensive treatment for respiratory failure. A variety of extrapulmonary sequelae of M pneumoniae infections have been described, including Stevens-Johnson syndrome. Macrolide resistance in M pneumoniae has developed rapidly in Asia, particularly in China, over the past decade and is now appearing in the United States. Emerging resistance to macrolides creates a therapeutic conundrum, particularly for pediatricians caring for young children in whom absolute or relative contraindications exist for the use of tetracyclines or fluoroquinolones, the 2 other main classes of drugs shown to be efficacious for M pneumoniae. We describe here the case of a child with a prolonged febrile illness associated with Stevens-Johnson\u2013like mucocutaneous involvement who was found to have a respiratory infection with macrolide-resistant M pneumoniae.<\/jats:p>","DOI":"10.1542\/peds.2010-2624","type":"journal-article","created":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T02:29:10Z","timestamp":1304389750000},"page":"e1605-e1609","source":"Crossref","is-referenced-by-count":21,"title":["Stevens-Johnson Syndrome in a Boy With Macrolide-Resistant<i>Mycoplasma pneumoniae<\/i>Pneumonia"],"prefix":"10.1542","volume":"127","author":[{"given":"T. Prescott","family":"Atkinson","sequence":"first","affiliation":[{"name":"Departments of Pediatrics,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Boppana","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Theos","sequence":"additional","affiliation":[{"name":"Dermatology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Scott","family":"Clements","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of South Alabama, Mobile, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xiao","sequence":"additional","affiliation":[{"name":"Pathology, University of Alabama at Birmingham, Birmingham, Alabama; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Waites","sequence":"additional","affiliation":[{"name":"Pathology, University of Alabama at Birmingham, Birmingham, Alabama; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2011,6,1]]},"reference":[{"issue":"4","key":"2021120900213136600_B1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.diagmicrobio.2010.03.004","article-title":"Characterization of macrolide resistance in Mycoplasma pneumoniae isolated from children in Shanghai, 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