{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T12:26:58Z","timestamp":1789734418165,"version":"4.0.1"},"reference-count":15,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE:<\/jats:title>\n                  <jats:p>To describe the characteristics and clinical courses of asthmatic children hospitalized with seasonal or 2009 pandemic H1N1 influenza and compare complications by influenza type.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>During the 2003\u20132009 influenza seasons and the 2009 pandemic, we conducted surveillance of 5.3 million children aged 17 years or younger for hospitalization with laboratory-confirmed influenza and identified those with asthma (defined as those aged 2\u201317 years with a history of asthma in their medical record or a discharge code for acute asthma exacerbation or status asthmaticus). We collected data from medical records on medical history and clinical course; data on asthma severity and control were not routinely collected.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>During the 2003\u20132009 influenza seasons, 701 (32%) of 2165 children hospitalized with influenza had asthma; during the 2009 pandemic, 733 (44%) of 1660 children had asthma. The median age of the asthmatic children was 7 years, and 73% had no additional medical conditions. Compared with asthmatic children with seasonal influenza, a higher proportion with 2009 pandemic H1N1 influenza required intensive care (16% vs 22%; P = .01) and were diagnosed with pneumonia (40% vs 46%; P = .04), whereas equal proportions had respiratory failure (5% vs 5%; P = .8) and died (1% vs 1%; P = .4). More asthmatic children with influenza A (seasonal or pandemic) had diagnoses of asthma exacerbations compared with those with influenza B (51% vs 29%; P &amp;lt; .01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>The majority of asthmatic children hospitalized with influenza have no additional medical conditions. Complications such as pneumonia and need for intensive care occur in a substantial proportion, highlighting the importance of influenza prevention through vaccination among asthmatic children.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2010-3343","type":"journal-article","created":{"date-parts":[[2011,6,7]],"date-time":"2011-06-07T03:16:38Z","timestamp":1307416598000},"page":"e27-e32","source":"Crossref","is-referenced-by-count":70,"title":["Children With Asthma Hospitalized With Seasonal or Pandemic Influenza, 2003\u20132009"],"prefix":"10.1542","volume":"128","author":[{"given":"Fatimah S.","family":"Dawood","sequence":"first","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie","family":"Kamimoto","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany A.","family":"D'Mello","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Reingold","sequence":"additional","affiliation":[{"name":"California Emerging Infections Program, Oakland, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Gershman","sequence":"additional","affiliation":[{"name":"Colorado Department of Public Health and Environment, Denver, Colorado;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Meek","sequence":"additional","affiliation":[{"name":"Connecticut Emerging Infections Program, Yale University, New Haven, Connecticut;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn E.","family":"Arnold","sequence":"additional","affiliation":[{"name":"Georgia Department of Community Health, Division of Public Health, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Farley","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine and the Atlanta Veterans Affairs Medical Center, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Ryan","sequence":"additional","affiliation":[{"name":"Maryland Department of Health and Mental Hygiene, Baltimore, Maryland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Lynfield","sequence":"additional","affiliation":[{"name":"Minnesota Department of Health, St Paul, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Morin","sequence":"additional","affiliation":[{"name":"Minnesota Department of Health, St Paul, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Baumbach","sequence":"additional","affiliation":[{"name":"New Mexico Department of Health, Santa Fe, New Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley","family":"Zansky","sequence":"additional","affiliation":[{"name":"Emerging Infections Program, New York State Department of Health, Albany, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Bennett","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Rochester School of Medicine and Dentistry and Monroe County Department of Health, Rochester, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Thomas","sequence":"additional","affiliation":[{"name":"Oregon Public Health Division, Portland, Oregon; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Schaffner","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kirschke","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyn","family":"Finelli","sequence":"additional","affiliation":[{"name":"Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Emerging Infections Program Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2011,7,1]]},"reference":[{"key":"2021120823581101800_B1","unstructured":"US Department of Health and Human Services. Summary health statistics for US children: National Health Interview Survey, 2008. Available at: www.cdc.gov\/nchs\/data\/series\/sr_10\/sr10_244.pdf. Accessed January 8, 2010"},{"issue":"RR-8","key":"2021120823581101800_B2","first-page":"1","article-title":"Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010","volume":"59","author":"Fiore","year":"2010","journal-title":"MMWR Recomm Rep"},{"issue":"1","key":"2021120823581101800_B3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.2007-1053","article-title":"Influenza burden for children with asthma","volume":"121","author":"Miller","year":"2008","journal-title":"Pediatrics"},{"issue":"6","key":"2021120823581101800_B4","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1067\/mpd.2000.110445","article-title":"The burden of influenza illness in children with asthma and other chronic medical conditions","volume":"137","author":"Neuzil","year":"2000","journal-title":"J Pediatr"},{"issue":"20","key":"2021120823581101800_B5","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1056\/NEJMoa0906695","article-title":"Hospitalized patients with 2009 H1N1 influenza in the United States, April\u2013June 2009","volume":"361","author":"Jain","year":"2009","journal-title":"N Engl J Med"},{"issue":"1","key":"2021120823581101800_B6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1503\/cmaj.091724","article-title":"Risk factors and outcomes among children admitted to hospital with pandemic H1N1 influenza","volume":"182","author":"O' Riordan","year":"2010","journal-title":"CMAJ"},{"issue":"4","key":"2021120823581101800_B7","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1093\/oxfordjournals.aje.a112704","article-title":"Influenza A and B virus infection in infants and young children during the years 1957\u20131976","volume":"109","author":"Kim","year":"1979","journal-title":"Am J Epidemiol"},{"issue":"7","key":"2021120823581101800_B8","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/INF.0b013e3181d411c5","article-title":"Influenza-associated pneumonia in children hospitalized with laboratory-confirmed influenza, 2003\u20132008","volume":"29","author":"Dawood","year":"2010","journal-title":"Pediatr Infect Dis J"},{"issue":"36","key":"2021120823581101800_B9","first-page":"1009","article-title":"Update: influenza activity: United States, April-August 2009","volume":"58","author":"Centers for Disease Control and Prevention (CDC)","year":"2009","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2021120823581101800_B10","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1016\/j.jaci.2007.09.029","article-title":"Guidelines for the diagnosis and management of asthma: summary report 2007","volume":"120","author":"National Asthma Education and Prevention Program","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"2021120823581101800_B11","first-page":"1","article-title":"Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009","volume":"58","author":"Fiore","year":"2009","journal-title":"MMWR Recomm Rep"},{"issue":"RR-8","key":"2021120823581101800_B12","first-page":"653","article-title":"Influenza vaccination coverage among persons with asthma: United States, 2005\u201306 influenza season","volume":"57","year":"2008","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"4","key":"2021120823581101800_B13","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1164\/rccm.200309-1251OC","article-title":"Influenza vaccination in children with asthma: randomized double-blind placebo-controlled trial","volume":"169","author":"Bueving","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"2021120823581101800_B14","first-page":"CD000364","article-title":"Vaccines for preventing influenza in people with asthma","author":"Cates","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"issue":"14","key":"2021120823581101800_B15","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1001\/jama.1994.03520140052037","article-title":"Efficacy of inactivated vaccine in preventing antigenically drifted influenza type A and well-matched type B","volume":"272","author":"Sugaya","year":"1994","journal-title":"JAMA"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/128\/1\/e27\/843979\/zpe00711000e27.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/128\/1\/e27\/843979\/zpe00711000e27.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T05:23:09Z","timestamp":1639027389000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/128\/1\/e27\/30354\/Children-With-Asthma-Hospitalized-With-Seasonal-or"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,1]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2011,7,1]]},"published-print":{"date-parts":[[2011,7,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2010-3343","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,1]]}}}