{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:06:01Z","timestamp":1788930361648,"version":"build-2803163510"},"reference-count":42,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,11,1]]},"abstract":"<jats:sec><jats:title>OBJECTIVE:<\/jats:title><jats:p>Hypoplastic left heart syndrome (HLHS) is one of the most serious congenital cardiac anomalies. Typically, it is managed with a series of 3 palliative operations or cardiac transplantation. Our goal was to quantify the inpatient resource burden of HLHS across multiple academic medical centers.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>The University HealthSystem Consortium is an alliance of 101 academic medical centers and 178 affiliated hospitals that share diagnostic, procedural, and financial data on all discharges. We examined inpatient resource use by patients with HLHS who underwent a staged palliative procedure or cardiac transplantation between 1998 and 2007.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>Among 1941 neonates, stage 1 palliation (Norwood or Sano procedure) had a median length of stay (LOS) of 25 days and charges of $214 680. Stage 2 and stage 3 palliation (Glenn and Fontan procedures, respectively) had median LOS and charges of 8 days and $82 174 and 11 days and $79 549, respectively. Primary neonatal transplantation had an LOS of 87 days and charges of $582 920, and rescue transplantation required 36 days and $411 121. The median inpatient wait time for primary and rescue transplants was 42 and 6 days, respectively. Between 1998 and 2007, the LOS for stage 1 palliation increased from 16 to 28 days and inflation-adjusted charges increased from $122 309 to $280 909, largely because of increasing survival rates (57% in 1998 and 83% in 2007).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Patients with HLHS demand considerable inpatient resources, whether treated with the Norwood-Glenn-Fontan procedure pathway or cardiac transplantation. Improved survival rates have led to increased hospital stays and costs.<\/jats:p><\/jats:sec>","DOI":"10.1542\/peds.2010-3742","type":"journal-article","created":{"date-parts":[[2011,10,11]],"date-time":"2011-10-11T02:11:26Z","timestamp":1318299086000},"page":"e1181-e1186","source":"Crossref","is-referenced-by-count":94,"title":["Inpatient Costs and Charges for Surgical Treatment of Hypoplastic Left Heart Syndrome"],"prefix":"10.1542","volume":"128","author":[{"given":"Peter N.","family":"Dean","sequence":"first","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane G.","family":"Hillman","sequence":"additional","affiliation":[{"name":"Public Health Sciences, University of Virginia Health System, Charlottesville, Virginia; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly E.","family":"McHugh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Medical University of 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