{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T17:59:58Z","timestamp":1789495198025,"version":"build-2803163510"},"reference-count":28,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Ankyloglossia has been associated with a variety of infant-feeding problems. Frenotomy commonly is performed for relief of ankyloglossia, but there has been a lack of convincing data to support this practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES:<\/jats:title>\n                    <jats:p>Our primary objective was to determine whether frenotomy for infants with ankyloglossia improved maternal nipple pain and ability to breastfeed. A secondary objective was to determine whether frenotomy improved the length of breastfeeding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Over a 12-month period, neonates who had difficulty breastfeeding and significant ankyloglossia were enrolled in this randomized, single-blinded, controlled trial and assigned to either a frenotomy (30 infants) or a sham procedure (28 infants). Breastfeeding was assessed by a preintervention and postintervention nipple-pain scale and the Infant Breastfeeding Assessment Tool. The same tools were used at the 2-week follow-up and regularly scheduled follow-ups over a 1-year period. The infants in the sham group were given a frenotomy before or at the 2-week follow-up if it was desired.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Both groups demonstrated statistically significantly decreased pain scores after the intervention. The frenotomy group improved significantly more than the sham group (P &amp;lt; .001). Breastfeeding scores significantly improved in the frenotomy group (P = .029) without a significant change in the control group. All but 1 parent in the sham group elected to have the procedure performed when their infant reached 2 weeks of age, which prevented additional comparisons between the 2 groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>We demonstrated immediate improvement in nipple-pain and breastfeeding scores, despite a placebo effect on nipple pain. This should provide convincing evidence for those seeking a frenotomy for infants with signficant ankyloglossia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1542\/peds.2011-0077","type":"journal-article","created":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T23:09:47Z","timestamp":1311030587000},"page":"280-288","source":"Crossref","is-referenced-by-count":158,"title":["Efficacy of Neonatal Release of Ankyloglossia: A Randomized Trial"],"prefix":"10.1542","volume":"128","author":[{"given":"Melissa","family":"Buryk","sequence":"first","affiliation":[{"name":"Naval Medical Center Portsmouth, Portsmouth, Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bloom","sequence":"additional","affiliation":[{"name":"Naval Medical Center Portsmouth, Portsmouth, Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Shope","sequence":"additional","affiliation":[{"name":"Naval Medical Center Portsmouth, 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