{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:20:10Z","timestamp":1791109210794,"version":"4.1.0"},"reference-count":18,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,3,1]]},"abstract":"<jats:p>Juvenile dermatomyositis is a rare systemic vasculopathy that may sometimes present with acute complications. We report here the case of a 7-year-old boy with severe dermatomyositis associated with thrombocytopenia and blurry vision. The presence of schistocytosis and the secondary occurrence of hemolytic anemia were consistent with a diagnosis of thrombotic thrombocytopenic purpura (TTP). Further investigations demonstrated the association of TTP with muscular microangiopathy and Purtscher-like retinopathy. Retinal and hematologic involvements dramatically improved after the initiation of plasma exchange in emergency. This report emphasizes that early recognition of TTP and prompt plasmapheresis are important in a child with severe juvenile dermatomyositis associated with thrombocytopenia.<\/jats:p>","DOI":"10.1542\/peds.2011-0338","type":"journal-article","created":{"date-parts":[[2012,2,7]],"date-time":"2012-02-07T04:56:57Z","timestamp":1328590617000},"page":"e821-e824","source":"Crossref","is-referenced-by-count":19,"title":["Thrombotic Microangiopathy and Purtscher-like Retinopathy as a Rare Presentation of Juvenile Dermatomyositis"],"prefix":"10.1542","volume":"129","author":[{"given":"Brigitte","family":"Bader-Meunier","sequence":"first","affiliation":[{"name":"Departments of Pediatric Immunology and Rheumatology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Monnet","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cochin Hospital, AP-HP, Paris, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Barnerias","sequence":"additional","affiliation":[{"name":"Pediatric Neurology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Halphen","sequence":"additional","affiliation":[{"name":"Paediatrics,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Lambot-Juhan","sequence":"additional","affiliation":[{"name":"Pediatric Radiology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Chalumeau","sequence":"additional","affiliation":[{"name":"Paediatrics,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Costedoat-Chalumeau","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, La Piti\u00e9-Salp\u00eatri\u00e8re Hospital, AP-HP, University Paris 6, Paris, France; 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