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The Pediatric Environmental History, a questionnaire developed in our clinic that is instrumental in determining environmental risk factors for tumor-related disease, was essential in documenting the presence or absence of risk factors considered as human carcinogens. We found a history of exposure to petroleum products in four cases of CFS that occurred at a greater than expected rate in a short time frame\u2013an apparent cancer cluster. We call attention to the possibility that exposure to petroleum products raises the risk of developing CFS. While future studies should focus on systematic investigation of CFS and its underlying mechanisms, this report suggests the need for proactive measures to avoid exposure to solvents and petroleum products during pregnancy.<\/jats:p>","DOI":"10.1542\/peds.2011-1307","type":"journal-article","created":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T00:25:58Z","timestamp":1346718358000},"page":"e1019-e1025","source":"Crossref","is-referenced-by-count":12,"title":["Congenital Fibrosarcoma and History of Prenatal Exposure to Petroleum Derivatives"],"prefix":"10.1542","volume":"130","author":[{"given":"Juan A.","family":"Ortega-Garc\u00eda","sequence":"first","affiliation":[{"name":"Pediatric Environmental Health Specialty Unit, Department of Pediatrics, University Hospital Virgen of Arrixaca, Murcia, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Offie P.","family":"Soldin","sequence":"additional","affiliation":[{"name":"Network PregnaTox, Department of Medicine, Oncology, Obstetrics & Gynecology, Pharmacology & Physiology, Georgetown University Medical Center, Washington DC;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando A.","family":"L\u00f3pez-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Quantitative Methods and Computing, Technical University of Cartagena, Cartagena, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Trasande","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Environmental Medicine, New York University School of Medicine, New York University Wagner School of Public Service, New York, New York; 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