{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T21:23:41Z","timestamp":1775251421302,"version":"3.50.1"},"reference-count":12,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,6,1]]},"abstract":"<jats:p>We present 2 term newborn infants with apneic seizure originating in the occipital lobe that was diagnosed by video-EEG. One infant had ischemic infarction in the distribution of the posterior cerebral artery, extending to the cingulate gyrus. In the other infant, only transient occipital hyperechogenicity was observed by using neurosonography. In both cases, although the critical EEG discharge was observed at the occipital level, the infants presented no clinical manifestations. In patient 1, the discharge extended to the temporal lobe first, with subtle motor manifestations and tachycardia, then synchronously to both hemispheres (with bradypnea\/hypopnea), and the background EEG activity became suppressed, at which point the infant experienced apnea. In patient 2, background EEG activity became suppressed right at the end of the focal discharge, coinciding with the appearance of apnea. In neither case did the clinical description by observers coincide with video-EEG findings. The existence of connections between the posterior limbic cortex and the temporal lobe and midbrain respiratory centers may explain the clinical symptoms recorded in these 2 cases. The novel features reported here include video-EEG capture of apneic seizure, ischemic lesion in the territory of the posterior cerebral artery as the cause of apneic seizure, and the appearance of apnea when the epileptiform ictal discharge extended to other cerebral areas or when EEG activity became suppressed. To date, none of these clinical findings have been previously reported. We believe this pathology may in fact be fairly common, but that video-EEG monitoring is essential for diagnosis.<\/jats:p>","DOI":"10.1542\/peds.2011-2447","type":"journal-article","created":{"date-parts":[[2012,5,29]],"date-time":"2012-05-29T00:24:14Z","timestamp":1338251054000},"page":"e1616-e1620","source":"Crossref","is-referenced-by-count":16,"title":["Neonatal Apneic Seizure of Occipital Lobe Origin: Continuous Video-EEG Recording"],"prefix":"10.1542","volume":"129","author":[{"given":"Jos\u00e9 Ram\u00f3n","family":"Castro Conde","sequence":"first","affiliation":[{"name":"Department of Neonatology, Hospital Universitario de Canarias, Tenerife, Spain; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom\u00e1s","family":"Gonz\u00e1lez-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Universidad de La Laguna, Tenerife, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desir\u00e9","family":"Gonz\u00e1lez Barrios","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Hospital Universitario de Canarias, Tenerife, Spain; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Candelaria","family":"Gonz\u00e1lez Campo","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Hospital Universitario de Canarias, Tenerife, Spain; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2012,6,1]]},"reference":[{"key":"2021120903481274700_B1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1749-6632.1988.tb37268.x","article-title":"Seizure-induced apnea.","volume":"533","author":"Monod","year":"1988","journal-title":"Ann N Y Acad Sci"},{"issue":"4","key":"2021120903481274700_B2","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ejpn.2008.07.005","article-title":"Apnoea in relation to neonatal temporal lobe haemorrhage.","volume":"13","author":"Hoogstraate","year":"2009","journal-title":"Eur J Paediatr Neurol"},{"issue":"5","key":"2021120903481274700_B3","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.pediatrneurol.2007.06.004","article-title":"Apneic seizures: a sign of temporal lobe hemorrhage in full-term neonates.","volume":"37","author":"Sirsi","year":"2007","journal-title":"Pediatr Neurol"},{"issue":"16","key":"2021120903481274700_B4","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1056\/NEJMcpc0801164","article-title":"Case records of the Massachusetts General Hospital. Case 12-2008. A newborn infant with intermittent apnea and seizures.","volume":"358","author":"Redline","year":"2008","journal-title":"N Engl J Med"},{"key":"2021120903481274700_B5","volume-title":"Neurology of the Newborn","author":"Volpe","year":"2008","edition":"5th ed."},{"issue":"3","key":"2021120903481274700_B6","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1136\/adc.2010.210054","article-title":"Question 1. 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