{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:23:58Z","timestamp":1792686238728,"version":"4.5.0"},"reference-count":39,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,7,1]]},"abstract":"<jats:sec><jats:title>OBJECTIVE:<\/jats:title><jats:p>The relationship between gestational hypertension, preeclampsia, and the risk of retinopathy of prematurity (ROP) remains unclear. Thus, we used a large cohort database to study the influence of maternal gestational hypertension and preeclampsia on the occurrence of ROP in preterm infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>We used data from a previous retrospective cohort study that includes 25\u2009473 eligible preterm neonates. We examined the association between gestational hypertension, preeclampsia, and ROP while controlling for potential confounders by multiple logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>Of the 8758 early preterm infants (gestational age &amp;lt;34 weeks), 1024 (11.69%) had ROP, while of the 16\u2009715 late preterm infants, only 29 (0.17%) had ROP. After adjusting for confounders, preeclampsia was associated with a significantly reduced risk of ROP (adjusted odds ratio [aOR], 0.65; 95% confidence interval [CI], 0.49\u20130.86 for early preterm birth; aOR, 0.10; 95% CI, 0.01\u20130.93 for late preterm birth; aOR, 0.66; 95% CI, 0.50\u20130.87 for all preterm births). Gestational hypertension was not significantly associated with ROP at early or late preterm births.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Preeclampsia, but not gestational hypertension, was associated with a reduced risk of ROP in preterm births.<\/jats:p><\/jats:sec>","DOI":"10.1542\/peds.2011-3881","type":"journal-article","created":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T09:47:46Z","timestamp":1338889666000},"page":"e101-e107","source":"Crossref","is-referenced-by-count":53,"title":["Preeclampsia and Retinopathy of Prematurity in Preterm Births"],"prefix":"10.1542","volume":"130","author":[{"given":"Xiao Dan","family":"Yu","sequence":"first","affiliation":[{"name":"MOE-Shanghai Key Laboratory of Children\u2019s Environmental Health, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Ware","family":"Branch","sequence":"additional","affiliation":[{"name":"Intermountain Healthcare and the University of Utah, Salt Lake City, Utah; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Ananth","family":"Karumanchi","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"MOE-Shanghai Key Laboratory of Children\u2019s Environmental Health, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2012,7,1]]},"reference":[{"issue":"7418","key":"2021120821260234200_B1","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1136\/bmj.327.7418.760","article-title":"Blindness in 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