{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:52:04Z","timestamp":1784033524766,"version":"3.55.0"},"reference-count":14,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,8,1]]},"abstract":"<jats:p>The management of a newborn born to a mother with chorioamnionitis is controversial. By using data collected on neonates born in the era of routine maternal screening for Group B Streptococcus, we calculate that the risk of early-onset sepsis in a hypothetical infant born at term to a mother with chorioamnionitis, who has a normal physical examination at birth, is likely substantially &amp;lt;1% if the mother\u2019s screen for Group B Streptococcus was negative. This low rate of sepsis calls into question current guidelines recommending treatment of all such newborns with intravenous antibiotics for 48 hours pending the results of a blood culture. Current guidelines for the management of infants born to mothers with chorioamnionitis also raise an important ethical issue; the recommendation to treat these infants with intravenous antibiotics is, in essence, a de facto determination of what constitutes unacceptable risk to the newborn. We argue that this determination is ultimately value-based and therefore requires broader deliberation than that which frequently occurs among medical experts who develop medical guidelines.<\/jats:p>","DOI":"10.1542\/peds.2012-0106","type":"journal-article","created":{"date-parts":[[2012,7,10]],"date-time":"2012-07-10T14:17:09Z","timestamp":1341929829000},"page":"342-346","source":"Crossref","is-referenced-by-count":28,"title":["Choriophobia: A 1-Act Play"],"prefix":"10.1542","volume":"130","author":[{"given":"James A.","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas J.","family":"Opel","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington; and"},{"name":"Treuman Katz Center for Pediatric Bioethics, Seattle Children\u2019s 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