{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:25:44Z","timestamp":1762503944728,"version":"3.40.5"},"reference-count":15,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,5,1]]},"abstract":"<jats:p>Bone lesions on radiographs of newborns often suggest congenital infections. Skeletal roentgenograms are recommended in the evaluation of suspected congenital syphilis, but bone lesions have been recognized in other congenital infections. We report the case of an infant with hydrops fetalis secondary to congenital parvovirus B19 infection who was found to have bone lesions in multiple long and axial bones on admission to the neonatal ICU. Both the infant and her mother were evaluated for other causes of congenital infection, but no other agents were identified. The bone lesions had nearly completely resolved by 10 weeks of age. Screening of neonates with congenital parvovirus B19 infection for bone lesions may provide additional insight into the incidence and pathophysiology of these lesions.<\/jats:p>","DOI":"10.1542\/peds.2012-0898","type":"journal-article","created":{"date-parts":[[2013,4,23]],"date-time":"2013-04-23T07:30:27Z","timestamp":1366702227000},"page":"e1659-e1663","source":"Crossref","is-referenced-by-count":10,"title":["Bone Lesions in an Infant With Congenital Parvovirus B19 Infection"],"prefix":"10.1542","volume":"131","author":[{"given":"Joseph B.","family":"Cantey","sequence":"first","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcia A.","family":"Pritchard","sequence":"additional","affiliation":[{"name":"Radiology, University of Texas Southwestern Medical Center, Dallas, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo J.","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2013,5,1]]},"reference":[{"key":"2021120900093692000_B1","first-page":"637","article-title":"Syphilis of the skeleton in early infancy; the nonspecificity of many of the roentgenographic changes.","volume":"42","author":"Caffey","year":"1939","journal-title":"Am J Roentgenol Radium Ther."},{"issue":"2","key":"2021120900093692000_B2","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0022-3476(69)80068-5","article-title":"Rubella bone lesions.","volume":"74","author":"Reed","year":"1969","journal-title":"J Pediatr"},{"issue":"3","key":"2021120900093692000_B3","first-page":"150","article-title":"Osseous changes in congenital toxoplasmosis.","volume":"97","author":"Milgram","year":"1974","journal-title":"Arch Pathol"},{"issue":"1","key":"2021120900093692000_B4","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1148\/10.1148\/94.1.39","article-title":"Rubella-like bone changes in congenital cytomegalic inclusion disease.","volume":"94","author":"Graham","year":"1970","journal-title":"Radiology"},{"issue":"4","key":"2021120900093692000_B5","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1469-8749.1977.tb07950.x","article-title":"Congenital herpes simplex type II infection with extensive hepatic calcification, bone lesions and cataracts: complete postmortem examination.","volume":"19","author":"Chalhub","year":"1977","journal-title":"Dev Med Child Neurol"},{"issue":"3","key":"2021120900093692000_B6","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1001\/jama.1940.02810290027007","article-title":"Syphlis of the bones in infancy: some possible errors in the roentgen diagnosis.","volume":"115","author":"Evans","year":"1940","journal-title":"JAMA"},{"issue":"2","key":"2021120900093692000_B7","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1136\/adc.50.2.160","article-title":"Bone changes in congenital cytomegalic inclusion disease.","volume":"50","author":"McCandless","year":"1975","journal-title":"Arch Dis Child"},{"issue":"1","key":"2021120900093692000_B8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcv.2006.01.004","article-title":"Parvovirus B19 infection in pregnancy.","volume":"36","author":"de Jong","year":"2006","journal-title":"J Clin Virol"},{"issue":"2","key":"2021120900093692000_B9","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/BF01641680","article-title":"Rubella embryopathy after previous maternal rubella vaccination.","volume":"12","author":"Enders","year":"1984","journal-title":"Infection"},{"issue":"3","key":"2021120900093692000_B10","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S0022-3476(88)80648-6","article-title":"Mineral excretion in premature infants receiving various diuretic therapies.","volume":"113","author":"Atkinson","year":"1988","journal-title":"J Pediatr"},{"issue":"1","key":"2021120900093692000_B11","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF00195223","article-title":"Persistent bony lesions in congenital syphilis. 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