{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:39:28Z","timestamp":1780915168733,"version":"3.54.1"},"reference-count":17,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,9,1]]},"abstract":"\n OBJECTIVE:<\/jats:title>\n Preterm infants are at increased risk of severe rotavirus gastroenteritis. Although immunization with rotavirus vaccine is safe and effective, age restrictions limit the number of infants eligible for vaccination at discharge from the NICU. The objectives of this study were to assess the implementation of the rotavirus vaccine program in our NICU, recognize missed opportunities for vaccination, and document how often very low birth weight (VLBW; birth weight \u22641500 g) and extremely low birth weight (ELBW; birth weight &lt;1000 g) infants were eligible to receive rotavirus vaccine at the time of NICU discharge.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n This study reports on a prospective, observational cohort of all VLBW infants who were discharged from the NICU at Parkland Memorial Hospital from May 2008 to April 2010. Medical records were reviewed and data collected regarding the number of infants who were eligible for and received rotavirus vaccination at discharge.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n A total of 63% (135 of 213) of VLBW infants did not receive rotavirus vaccine. The reasons for not providing vaccine included the following: &lt;42 days of age at discharge (56 of 213; 26%), &gt;84 or 104 days of age at discharge (48 of 213; 23%), or missed (35 of 213; 16%). The majority (75%) who were too old for vaccination at the time of discharge were ELBW.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n The current age restrictions for rotavirus immunization resulted in more than half of ELBW infants being ineligible for vaccination at the time of discharge from the NICU. Alternative strategies for rotavirus immunization in this population are needed.<\/jats:p>\n <\/jats:sec>","DOI":"10.1542\/peds.2013-0291","type":"journal-article","created":{"date-parts":[[2013,8,13]],"date-time":"2013-08-13T00:25:48Z","timestamp":1376353548000},"page":"e662-e665","source":"Crossref","is-referenced-by-count":40,"title":["Rotavirus Vaccination of Very Low Birth Weight Infants at Discharge From the NICU"],"prefix":"10.1542","volume":"132","author":[{"given":"Katherine A.","family":"Stumpf","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tami","family":"Thompson","sequence":"additional","affiliation":[{"name":"Women & Infants\u2019 Specialty Health, Parkland Health and Hospital System, Dallas, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo J.","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2013,9,1]]},"reference":[{"key":"2021120902584089400_B1","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1097\/INF.0b013e3181967bee","article-title":"Rotavirus overview.","volume":"28","author":"Bernstein","year":"2009","journal-title":"Pediatr Infect Dis J"},{"key":"2021120902584089400_B2","first-page":"1","article-title":"Prevention of rotavirus gastroenteritis among infants and children: recommendations of the Advisory Committee on Immunization Practices (ACIP).","volume":"58","author":"Cortese","year":"2009","journal-title":"MMWR Recomm Rep"},{"issue":"1","key":"2021120902584089400_B3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1056\/NEJMoa052664","article-title":"Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine.","volume":"354","author":"Vesikari","year":"2006","journal-title":"N Engl J Med"},{"issue":"2","key":"2021120902584089400_B4","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2009-1021","article-title":"Effectiveness of pentavalent rotavirus vaccine in a large urban population in the United States.","volume":"125","author":"Boom","year":"2010","journal-title":"Pediatrics"},{"issue":"1","key":"2021120902584089400_B5","doi-asserted-by":"crossref","DOI":"10.1542\/peds.103.1.e3","article-title":"Perinatal risk factors for infant hospitalization with viral gastroenteritis.","volume":"103","author":"Newman","year":"1999","journal-title":"Pediatrics"},{"issue":"12","key":"2021120902584089400_B6","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1097\/01.inf.0000243777.01375.5b","article-title":"A case-control study to determine risk factors for hospitalization for rotavirus gastroenteritis in U.S. children.","volume":"25","author":"Dennehy","year":"2006","journal-title":"Pediatr Infect Dis J"},{"issue":"5","key":"2021120902584089400_B7","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1542\/peds.2009-0466","article-title":"Prevention of rotavirus disease: updated guidelines for use of rotavirus vaccine.","volume":"123","author":"American Academy of Pediatrics Committee on Infectious Diseases","year":"2009","journal-title":"Pediatrics"},{"key":"2021120902584089400_B8","first-page":"576","article-title":"Rotavirus Infections","volume-title":"Red Book 2009: Report of the Committee on Infectious Diseases","author":"American Academy of Pediatrics","year":"2009"},{"issue":"5","key":"2021120902584089400_B9","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1097\/INF.0b013e3182490a2c","article-title":"Safety, reactogenicity and immunogenicity of the human rotavirus vaccine in preterm European infants: a randomized phase IIIb study.","volume":"31","author":"Omenaca","year":"2012","journal-title":"Pediatr Infect Dis J"},{"issue":"12","key":"2021120902584089400_B10","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/INF.0b013e31814521cb","article-title":"Safety and efficacy of the pentavalent human-bovine (WC3) reassortant rotavirus vaccine in healthy premature infants.","volume":"26","author":"Goveia","year":"2007","journal-title":"Pediatr Infect Dis J"},{"issue":"3","key":"2021120902584089400_B11","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1542\/peds.2012-3769","article-title":"Annual summary of vital statistics: 2010-2011.","volume":"131","author":"Hamilton","year":"2013","journal-title":"Pediatrics"},{"issue":"22","key":"2021120902584089400_B12","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1016\/j.vaccine.2009.03.016","article-title":"Broadening the age restriction for initiating rotavirus vaccination in regions with high rotavirus mortality: benefits of mortality reduction versus risk of fatal intussusception.","volume":"27","author":"Patel","year":"2009","journal-title":"Vaccine"},{"issue":"6","key":"2021120902584089400_B13","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1086\/500217","article-title":"Age dependence of the relation between reassortant rotavirus vaccine (RotaShield) and intussusception.","volume":"193","author":"Rothman","year":"2006","journal-title":"J Infect Dis"},{"key":"2021120902584089400_B14","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1086\/431512","article-title":"More on RotaShield and intussusception: the role of age at the time of vaccination.","volume":"192","author":"Simonsen","year":"2005","journal-title":"J Infect Dis"},{"issue":"51","key":"2021120902584089400_B15","doi-asserted-by":"crossref","first-page":"9508","DOI":"10.1016\/j.vaccine.2011.10.015","article-title":"Horizontal transmission of a human rotavirus vaccine strain\u2014a randomized, placebo-controlled study in 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