{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T14:05:42Z","timestamp":1792850742179,"version":"4.5.0"},"reference-count":49,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To estimate the associations between autism spectrum disorder (ASD) diagnoses and service use, caregiver time, and cost outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We used national data from the Medical Expenditure Panel Survey linked to the National Health Interview Survey and a study-specific survey to estimate the annual utilization and costs for health care, school, ASD-related therapy, family-coordinated services, as well as caregiver time in children aged 3 to 17 years, with and without parent-reported ASD. Regression analyses estimated the association between ASD diagnosis and cost, controlling for child gender, age, race\/ethnicity, insurance status, household income, country region and urban\/rural classification, and non\u2013ASD-related illnesses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Children with parent-reported ASD had higher levels of health care office visits and prescription drug use compared with children without ASD (P &amp;lt; .05). A greater proportion of children in the ASD group used special educational services (76% vs 7% in the control group, P &amp;lt; .05). After adjusting for child demographic characteristics and non\u2013ASD-associated illnesses, ASD was associated with $3020 (95% confidence interval [CI]: $1017\u2013$4259) higher health care costs and $14\u2009061 (95% CI: $4390\u2013$24\u2009302) higher aggregate non\u2013health care costs, including $8610 (95% CI: $6595\u2013$10\u2009421) higher school costs. In adjusted analyses, parents who reported that their child had ASD did not have significantly higher out-of-pocket costs or spend more time on caregiving activities compared with control parents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The economic burden associated with ASD is substantial and can be measured across multiple sectors of our society. Previous analyses that focused on health care underestimated this economic burden, particularly for school systems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1542\/peds.2013-0763","type":"journal-article","created":{"date-parts":[[2014,2,10]],"date-time":"2014-02-10T21:11:16Z","timestamp":1392066676000},"page":"e520-e529","source":"Crossref","is-referenced-by-count":412,"title":["Economic Burden of Childhood Autism Spectrum Disorders"],"prefix":"10.1542","volume":"133","author":[{"given":"Tara A.","family":"Lavelle","sequence":"first","affiliation":[{"name":"PhD Program in Health Policy, Harvard University, Cambridge, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milton C.","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P.","family":"Newhouse","sequence":"additional","affiliation":[{"name":"Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerim","family":"Munir","sequence":"additional","affiliation":[{"name":"Division of Developmental Medicine, Boston Children\u2019s Hospital, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen A.","family":"Kuhlthau","sequence":"additional","affiliation":[{"name":"Center for Child and Adolescent Health Research and Policy, Massachusetts General Hospital, Boston, Massachusetts; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A.","family":"Prosser","sequence":"additional","affiliation":[{"name":"Child Health Evaluation and Research Unit, Division of General Pediatrics, University of Michigan Health System, Ann Arbor, 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