{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T13:36:06Z","timestamp":1746711366425,"version":"3.40.5"},"reference-count":16,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,1]]},"abstract":"<jats:p>Posterior reversible cerebral edema syndrome is a generally reversible neurologic condition that is diagnosed based on distinctive clinical and radiologic findings. The condition, which is mostly associated with severe arterial hypertension, has also been reported to be induced by several medications. We made the diagnosis of hypertension with posterior reversible cerebral edema syndrome in a lean 12-year-old girl treated with the second-generation antipsychotic risperidone. We applied the Naranjo Adverse Drug Reaction Probability Scale and the World Health Organization\u2013Uppsala Monitoring Centre system for causality assessment to the present case. Both scales indicated that a relationship to risperidone was likely. Second-generation antipsychotic agents may occasionally induce an increase in blood pressure even in the absence of overweight. Given this possibility, we recommend routine monitoring of blood pressure during therapy with these agents.<\/jats:p>","DOI":"10.1542\/peds.2013-1301","type":"journal-article","created":{"date-parts":[[2014,2,25]],"date-time":"2014-02-25T02:19:49Z","timestamp":1393294789000},"page":"e771-e774","source":"Crossref","is-referenced-by-count":5,"title":["Arterial Hypertension and Posterior Reversible Cerebral Edema Syndrome Induced by Risperidone"],"prefix":"10.1542","volume":"133","author":[{"given":"Gregorio Paolo","family":"Milani","sequence":"first","affiliation":[{"name":"Pediatric Emergency Department,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Giovanni","family":"Bianchetti","sequence":"additional","affiliation":[{"name":"Division of Pediatrics, Mendrisio and Bellinzona Hospitals and University of Berne, Berne, Switzerland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta Benedetta Maria","family":"Mazzoni","sequence":"additional","affiliation":[{"name":"Pediatric Emergency Department,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Triulzi","sequence":"additional","affiliation":[{"name":"Neuroradiology Department, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo Carlo","family":"Mauri","sequence":"additional","affiliation":[{"name":"Clinical Psychiatry, Clinical Neuropsychopharmacology, Foundation IRCCS Ca\u2019 Granda, Ospedale Maggiore Policlinico, Milan, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Agostoni","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences and Community Health, University of Milan, IRCCS Ospedale Maggiore Policlinico, Pediatric Clinic 2, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio Filippo","family":"Fossali","sequence":"additional","affiliation":[{"name":"Pediatric 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