{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T14:09:46Z","timestamp":1769436586626,"version":"3.49.0"},"reference-count":14,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,11,1]]},"abstract":"\n BACKGROUND AND OBJECTIVE:<\/jats:title>\n Therapeutic hypothermia is now the standard of care for hypoxic-ischemic encephalopathy. Treatment should be started early, and it is often necessary to transfer the infant to a regional NICU for ongoing care. There are no large studies reporting outcomes from infants cooled passively compared with active (servo-controlled) cooling during transfer. Our goal was to review data from a regional transport service, comparing both methods of cooling.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n This was a retrospective observational study of 143 infants referred to a regional NICU for ongoing therapeutic hypothermia. Of the 134 infants transferred, the first 64 were cooled passively, and 70 were subsequently cooled after purchase of a servo-controlled mattress. Key outcome measures were time to arrival at the regional unit, temperature at referral and arrival at the regional unit, and temperature stability during transfer.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n The age cooling was started was significantly shorter in the actively cooled group (46 [0\u2013352] minutes vs 120 [0\u2013502] minutes; P &lt;.01). The median (range) stabilization time (153 [60\u2013385] minutes vs 133 [45\u2013505] minutes; P = .04) and age at arrival at the regional unit (504 [191\u2013924] minutes vs 452 [225\u20131265]) minutes; P = .01) were significantly shorter in the actively cooled group. Only 39% of infants passively cooled were within the target temperature range at arrival to the regional unit compared with 100% actively cooled.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Servo-controlled active cooling has been shown to improve temperature stability and is associated with a reduction in transfer time.<\/jats:p>\n <\/jats:sec>","DOI":"10.1542\/peds.2013-1686","type":"journal-article","created":{"date-parts":[[2013,10,22]],"date-time":"2013-10-22T00:48:33Z","timestamp":1382402913000},"page":"841-846","source":"Crossref","is-referenced-by-count":68,"title":["Active Versus Passive Cooling During Neonatal Transport"],"prefix":"10.1542","volume":"132","author":[{"given":"Rajiv","family":"Chaudhary","sequence":"first","affiliation":[{"name":"Acute Neonatal Transfer Service for the East of England and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Farrer","sequence":"additional","affiliation":[{"name":"Acute Neonatal Transfer Service for the East of England and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Broster","sequence":"additional","affiliation":[{"name":"Acute Neonatal Transfer Service for the East of England and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"McRitchie","sequence":"additional","affiliation":[{"name":"Acute Neonatal Transfer Service for the East of England and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Topun","family":"Austin","sequence":"additional","affiliation":[{"name":"Neonatal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2013,11,1]]},"reference":[{"key":"2021120903055375000_B1"},{"key":"2021120903055375000_B2"},{"key":"2021120903055375000_B3","unstructured":"National Institute for Health and Clinical Excellence. NICE IPG374: therapeutic hypothermia with intracorporeal temperature monitoring for hypoxic perinatal brain injury: guidance. Available at: www.nice.org.uk\/nicemedia\/live\/11315\/48809\/48809.pdf. Accessed September 24, 2013"},{"key":"2021120903055375000_B4","unstructured":"BAPM. Position statement on therapeutic cooling for neonatal encephalopathy. Available at: www.bapm.org\/publications\/documents\/guidelines\/ Position_Statement_Therapeutic_Cooling_Neonatal_Encephalopathy_July%202010.pdf. Accessed September 24, 2013"},{"key":"2021120903055375000_B5"},{"key":"2021120903055375000_B6"},{"key":"2021120903055375000_B7"},{"key":"2021120903055375000_B8"},{"key":"2021120903055375000_B9","unstructured":"Walston FE, Baron M, Farrer KF, et al. A regional approach to the early management of infants with hypoxic-ischaemic encephalopathy. Neonatal Society Abstract. Available at: www.neonatalsociety.ac.uk\/abstracts\/walstonf_2011_regionalhie.shtml. Accessed September 24, 2013"},{"issue":"2","key":"2021120903055375000_B10","first-page":"1197","article-title":"Burnard E, Cross K. Rectal temperature in the newborn after birth asphyxia.","volume":"15","year":"1958","journal-title":"BMJ"},{"key":"2021120903055375000_B11"},{"key":"2021120903055375000_B12"},{"key":"2021120903055375000_B13"},{"issue":"8","key":"2021120903055375000_B14","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/j.1651-2227.2011.02249.x","article-title":"Therapeutic hypothermia during neonatal transport.","volume":"100","author":"O\u2019Reilly","year":"2011","journal-title":"Acta Paediatr"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/132\/5\/841\/1099190\/peds_2013-1686.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/132\/5\/841\/1099190\/peds_2013-1686.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T16:27:48Z","timestamp":1639067268000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/132\/5\/841\/31778\/Active-Versus-Passive-Cooling-During-Neonatal"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,1]]},"references-count":14,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2013,11,1]]},"published-print":{"date-parts":[[2013,11,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2013-1686","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,1]]}}}