{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:05:10Z","timestamp":1777356310046,"version":"3.51.4"},"reference-count":24,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE:<\/jats:title>\n                  <jats:p>To assess longitudinally children\u2019s motor performance 5 to 12 years after neonatal extracorporeal membrane oxygenation (ECMO) and to evaluate associations between clinical characteristics and motor performance.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>Two hundred fifty-four neonatal ECMO survivors in the Netherlands were tested with the Movement Assessment Battery for Children at 5, 8, and\/or 12 years. Percentile scores were transformed to z scores for longitudinal evaluation (norm population mean = 0 and SD = 1). Primary diagnoses: meconium aspiration syndrome (n = 137), congenital diaphragmatic hernia (n = 49), persistent pulmonary hypertension of the newborn (n = 36), other diagnoses (n = 32).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>Four hundred fifty-six tests were analyzed. At 5, 8, and 12 years motor performance was normal in 73.7, 74.8, and 40.5%, respectively (vs 85% expected based on reference values; P &amp;lt; .001 at all ages). In longitudinal analyses mean (95% confidence interval [CI]) z scores were \u20130.42 (\u20130.55 to \u20130.28), \u20130.25 (\u20130.40 to \u20130.10) and \u20131.00 (\u20131.26 to \u20130.75) at 5, 8, and 12 years, respectively. Mean score at 8 years was significantly higher than at 5 years (difference 0.16, 95% CI 0.02 to 0.30), and mean score at 12 years was significantly lower than at both other ages (differences \u20130.59 and \u20130.75; 95% CI \u20130.33 to \u20130.84 and \u20130.49 to \u20131.00, respectively). Children with congenital diaphragmatic hernia encountered problems at all ages. The presence of chronic lung disease was negatively related with outcome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Motor problems in neonatal ECMO survivors persist throughout childhood and become more obvious with time.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2013-3351","type":"journal-article","created":{"date-parts":[[2014,7,22]],"date-time":"2014-07-22T03:53:39Z","timestamp":1406001219000},"page":"e427-e435","source":"Crossref","is-referenced-by-count":33,"title":["Motor Performance After Neonatal Extracorporeal Membrane Oxygenation: A Longitudinal Evaluation"],"prefix":"10.1542","volume":"134","author":[{"given":"Monique H.M.","family":"van der Cammen-van Zijp","sequence":"first","affiliation":[{"name":"Intensive Care and Department of Pediatric Surgery,"},{"name":"Department of Rehabilitation Medicine and Physical Therapy, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anjo J.W.M.","family":"Janssen","sequence":"additional","affiliation":[{"name":"Departments of Rehabilitation, Pediatric Physical Therapy, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlou MA","family":"Raets","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Erasmus Medical Center\u2013Sophia Children\u2019s Hospital, Rotterdam, Netherlands;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joost","family":"van Rosmalen","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Erasmus Medical Center, Rotterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Govaert","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Erasmus Medical Center\u2013Sophia Children\u2019s Hospital, Rotterdam, Netherlands;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerina","family":"Steiner","sequence":"additional","affiliation":[{"name":"Neonatology, Radboud University Medical Center, Nijmegen, Netherlands; 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