{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T22:04:38Z","timestamp":1780351478545,"version":"3.54.1"},"reference-count":28,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,9,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND AND OBJECTIVES:<\/jats:title>\n                  <jats:p>It has been suggested that there is a causal relationship between hypoxia and subdural hemorrhage (SDH) in infancy. The purpose of this study was to review the incidence of SDH in infants with congenital heart disease and explore the relationship between SDH and hypoxia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>Review of data collected for a prospective longitudinal cohort study of infants undergoing surgery for congenital heart disease in New Zealand and Australia. Infants underwent serial MRI scans of the brain in the first 3 months of life. All oxygen saturation recordings and MRI results were extracted and infants assigned to categories by degree of hypoxia. The data were then examined for any statistically significant relationship between hypoxia and SDH.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>One hundred fifty-two infants underwent MRI scans, and 66 (43%) had 145 loci of SDH. New SDH was seen in 12 infants after cardiac surgery. Of the loci of SDH, 63 (43%) were supratentorial, and most of these were interhemispheric, parietal, or temporal. SDH present on the first MRI persisted beyond 28 days of life in 8 infants. There was no demonstrable relationship between SDH and hypoxia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Asymptomatic SDH is common in young infants with congenital heart disease, at a frequency similar to that of those without congenital heart disease. These SDHs may occur in locations where they occur in abusive head trauma, but they are typically small and resolve within 3 months of birth. We were unable to demonstrate any association between hypoxia and SDH in this cohort.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2013-3903","type":"journal-article","created":{"date-parts":[[2014,8,26]],"date-time":"2014-08-26T05:14:44Z","timestamp":1409030084000},"page":"e773-e781","source":"Crossref","is-referenced-by-count":30,"title":["Subdural Hemorrhage and Hypoxia in Infants With Congenital Heart Disease"],"prefix":"10.1542","volume":"134","author":[{"given":"Patrick","family":"Kelly","sequence":"first","affiliation":[{"name":"Te Puaruruhau (Child Protection Team),"},{"name":"Department of Pediatrics, Faculty of Medical and Health Sciences, University of Auckland, New Zealand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Hayman","sequence":"additional","affiliation":[{"name":"Children\u2019s Emergency Department,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara S.","family":"Shekerdemian","sequence":"additional","affiliation":[{"name":"Section of Critical Care Medicine, Texas Children\u2019s Hospital, Houston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Reed","sequence":"additional","affiliation":[{"name":"Children\u2019s Research Centre, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayton","family":"Hope","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Auckland City Hospital, Auckland, New Zealand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Gunn","sequence":"additional","affiliation":[{"name":"Departments of Neonatal Medicine, and"},{"name":"Murdoch Children\u2019s Research Institute, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Coleman","sequence":"additional","affiliation":[{"name":"Radiology, The Royal Children\u2019s Hospital, Melbourne, Australia; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Beca","sequence":"additional","affiliation":[{"name":"Pediatric ICU, Starship Children\u2019s Hospital, Auckland, New Zealand;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2014,9,1]]},"reference":[{"key":"2021120908524225000_B1","volume-title":"Pediatric Abusive Head Trauma: Recommended Definitions for Public Health Surveillance and Research","author":"Parks","year":"2012"},{"issue":"5","key":"2021120908524225000_B2","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1542\/peds.2009-0408","article-title":"Abusive head trauma in infants and children.","volume":"123","author":"Christian","year":"2009","journal-title":"Pediatrics"},{"issue":"pt 7","key":"2021120908524225000_B3","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1093\/brain\/124.7.1290","article-title":"Neuropathology of inflicted head injury in children. 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