{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:15:02Z","timestamp":1787022902025,"version":"build-2736575974"},"reference-count":25,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n                    <jats:p>Evolving data indicate that cord clamping (CC) beyond 30 to 60 seconds after birth is of benefit for all infants. Recent experimental data demonstrated that ventilation before CC improved cardiovascular stability by increasing pulmonary blood flow. The objective was to describe the relationship between time to CC, onset of spontaneous respirations (SR), and 24-hour neonatal outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>In a rural Tanzanian hospital, trained research assistants, working in shifts, have observed every delivery (November 2009\u2013February 2013) and recorded data including time interval from birth to SR and CC, fetal heart rate, perinatal characteristics and outcome (normal, death, admission).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Of 15\u2009563 infants born, 12\u2009780 (84.3%) initiated SR at 10.8 \u00b1 16.7 seconds, and CC occurred at 63 \u00b1 45 seconds after birth. Outcomes included 12\u2009730 (99.7%) normal, 31 deaths, and 19 admitted; 11\u2009967 were of birth weight (BW) \u22652500 g and 813 &amp;lt;2500\u00a0g. By logistic modeling, the risk of death\/admission was consistently higher if CC occurred before SR. Infants of BW &amp;lt;2500\u00a0g were more likely to die or be admitted. The risk of death\/admission decreased by 20% for every 10-second delay in CC after SR; this risk declined at the same rate in both BW groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Healthy self-breathing neonates are more likely to die or be admitted if CC occurs before or immediately after onset of SR. These clinical observations support the experimental findings of a smoother cardiovascular transition when CC is performed after initiation of ventilation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1542\/peds.2014-0467","type":"journal-article","created":{"date-parts":[[2014,7,14]],"date-time":"2014-07-14T22:14:47Z","timestamp":1405376087000},"page":"265-272","source":"Crossref","is-referenced-by-count":105,"title":["Neonatal Outcome Following Cord Clamping After Onset of Spontaneous Respiration"],"prefix":"10.1542","volume":"134","author":[{"given":"Hege Langli","family":"Ersdal","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, and"},{"name":"SAFER (Stavanger Acute medicine Foundation for Education and Research), Stavanger University Hospital, Norway; Departments of"},{"name":"Health Studies, 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