{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T04:01:45Z","timestamp":1794024105879,"version":"4.8.0"},"reference-count":58,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,7,1]]},"abstract":"<jats:p>Vascular anomalies represent a spectrum of disorders from a simple \u201cbirthmark\u201d to life- threatening entities. Incorrect nomenclature and misdiagnoses are commonly experienced by patients with these anomalies. Accurate diagnosis is crucial for appropriate evaluation and management, often requiring multidisciplinary specialists. Classification schemes provide a consistent terminology and serve as a guide for pathologists, clinicians, and researchers. One of the goals of the International Society for the Study of Vascular Anomalies (ISSVA) is to achieve a uniform classification. The last classification (1997) stratified vascular lesions into vascular malformations and proliferative vascular lesions (tumors). However, additional disease entities have since been identified that are complex and less easily classified by generic headings, such as capillary malformation, venous malformation, lymphatic malformation, etc. We hereby present the updated official ISSVA classification of vascular anomalies. The general biological scheme of the classification is retained. The section on tumors has been expanded and lists the main recognized vascular tumors, classified as benign, locally aggressive or borderline, and malignant. A list of well-defined diseases is included under each generic heading in the \u201cSimple Vascular Malformations\u201d section. A short definition is added for eponyms. Two new sections were created: one dealing with the malformations of individually named vessels (previously referred to as \u201ctruncular\u201d malformations); the second groups lesions of uncertain or debated nature (tumor versus malformation). The known genetic defects underlying vascular anomalies are included in an appendix. This classification is meant to be a framework, acknowledging that it will require modification as new scientific information becomes available.<\/jats:p>","DOI":"10.1542\/peds.2014-3673","type":"journal-article","created":{"date-parts":[[2015,6,10]],"date-time":"2015-06-10T10:25:33Z","timestamp":1433931933000},"page":"e203-e214","source":"Crossref","is-referenced-by-count":1206,"title":["Vascular Anomalies Classification: Recommendations From the International Society for the Study of Vascular Anomalies"],"prefix":"10.1542","volume":"136","author":[{"given":"Michel","family":"Wassef","sequence":"first","affiliation":[{"name":"Assistance Publique\u2013Hopitaux de Paris, Lariboisi\u00e8re Hospital, Department of Pathology, Paris Diderot University, Paris, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine","family":"Blei","sequence":"additional","affiliation":[{"name":"Vascular Birthmark Program, Lenox Hill Hospital of North Shore Long Island Jewish 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