{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:04:21Z","timestamp":1791266661978,"version":"4.1.0"},"reference-count":8,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,12,1]]},"abstract":"<jats:p>Q fever osteomyelitis, caused by infection with Coxiella burnetti, is rare but should be included in the differential diagnosis of children with culture-negative osteomyelitis, particularly if there is a history of contact with farm animals, and\/or granulomatous change on histologic examination of a bone biopsy specimen. We describe a case of Q fever osteomyelitis in a 6-year-old boy in which a decision was made not to treat the patient with combination antimicrobial agents, balancing possible risks of recurrence against potential side effects of prolonged antibiotic treatment. The patient had undergone surgical debridement of a single lesion and was completely asymptomatic after recovery from surgery. This case suggests that a conservative approach of watchful waiting in an asymptomatic patient with chronic Q fever osteomyelitis may be warranted in select cases when close follow-up is possible.<\/jats:p>","DOI":"10.1542\/peds.2015-0024","type":"journal-article","created":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T01:53:04Z","timestamp":1447725184000},"page":"e1629-e1631","source":"Crossref","is-referenced-by-count":10,"title":["A Case of Pediatric Q Fever Osteomyelitis Managed Without Antibiotics"],"prefix":"10.1542","volume":"136","author":[{"given":"Ameneh","family":"Khatami","sequence":"first","affiliation":[{"name":"Department of Microbiology and Infectious Diseases, The Children\u2019s Hospital at Westmead, Sydney, Australia; and"},{"name":"University of Sydney, School of Medicine, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca T.","family":"Sparks","sequence":"additional","affiliation":[{"name":"University of Sydney, School of Medicine, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben J.","family":"Marais","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases, The Children\u2019s Hospital at Westmead, Sydney, Australia; and"},{"name":"University of Sydney, School of Medicine, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2015,12,1]]},"reference":[{"issue":"10","key":"2021120906143354900_B1","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s10096-011-1225-y","article-title":"Q fever seroprevalence in metropolitan samples is similar to rural\/remote samples in Queensland, Australia.","volume":"30","author":"Tozer","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"11","key":"2021120906143354900_B2","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/S1473-3099(02)00440-1","article-title":"Q fever in children.","volume":"2","author":"Maltezou","year":"2002","journal-title":"Lancet Infect Dis"},{"key":"2021120906143354900_B3","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1471-2334-10-69","article-title":"The use of a geographic information system to identify a dairy goat farm as the most likely source of an urban Q-fever outbreak.","volume":"10","author":"Schimmer","year":"2010","journal-title":"BMC Infect Dis"},{"issue":"4","key":"2021120906143354900_B4","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S1473-3099(05)70052-9","article-title":"Natural history and pathophysiology of Q fever.","volume":"5","author":"Raoult","year":"2005","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"2021120906143354900_B5","doi-asserted-by":"crossref","first-page":"540","DOI":"10.4269\/ajtmh.2004.70.540","article-title":"Q fever in children in Greece.","volume":"70","author":"Maltezou","year":"2004","journal-title":"Am J Trop Med Hyg"},{"issue":"7","key":"2021120906143354900_B6","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1086\/424014","article-title":"Three cases of Q fever osteomyelitis in children and a review of the literature.","volume":"39","author":"Nourse","year":"2004","journal-title":"Clin Infect Dis"},{"issue":"4","key":"2021120906143354900_B7","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1128\/CMR.12.4.518","article-title":"Q fever.","volume":"12","author":"Maurin","year":"1999","journal-title":"Clin Microbiol Rev"},{"issue":"5","key":"2021120906143354900_B8","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s10096-007-0285-5","article-title":"Q fever osteoarticular infection: four new cases and a review of the literature.","volume":"26","author":"Landais","year":"2007","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/136\/6\/e1629\/1062189\/peds_2015-0024.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/136\/6\/e1629\/1062189\/peds_2015-0024.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T00:21:05Z","timestamp":1639095665000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/136\/6\/e1629\/33870\/A-Case-of-Pediatric-Q-Fever-Osteomyelitis-Managed"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,1]]},"references-count":8,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,12,1]]},"published-print":{"date-parts":[[2015,12,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2015-0024","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,1]]}}}