{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:38:50Z","timestamp":1791988730419,"version":"4.4.0"},"reference-count":31,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,2,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n                  <jats:p>Children with neurologic impairment (NI) are commonly hospitalized for different types of pneumonia, including aspiration pneumonia. We sought to compare hospital management and outcomes of children with NI diagnosed with aspiration versus nonaspiration pneumonia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>A retrospective study of 27\u2009455 hospitalized children aged 1 to 18 years with NI diagnosed with pneumonia from 2007 to 2012 at 40 children\u2019s hospitals in the Pediatric Health Information System database. The primary exposure was pneumonia type, classified as aspiration or nonaspiration. Outcomes were complications (eg, acute respiratory failure) and hospital utilization (eg, length of stay, 30-day readmission). Multivariable regression was used to assess the association between pneumonia type and outcomes, adjusting for NI type, comorbid conditions, and other characteristics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>In multivariable analysis, the 9.7% of children diagnosed with aspiration pneumonia experienced more complications than children with nonaspiration pneumonia (34.0% vs 15.2%, adjusted odds ratio [aOR] 1.2 (95% confidence interval [CI] 1.1\u20131.3). Children with aspiration pneumonia had significantly longer length of stay (median 5 vs 3 days; ratio of means 1.2; 95% CI 1.2\u20131.3); more ICU transfers (4.3% vs 1.5%; aOR 1.4; 95% CI 1.1\u20131.9); greater hospitalization costs (median $11\u2009594 vs $5162; ratio of means 1.2; 95% CI 1.2\u20131.3); and more 30-day readmissions (17.4% vs 6.8%; aOR 1.3; 95% CI 1.2\u20131.5).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Hospitalized children with NI diagnosed with aspiration pneumonia have more complications and use more hospital resources than when diagnosed with nonaspiration pneumonia. Additional investigation is needed to understand the reasons for these differences.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2015-1612","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T02:20:16Z","timestamp":1453256416000},"source":"Crossref","is-referenced-by-count":55,"title":["Aspiration and Non-Aspiration Pneumonia in Hospitalized Children With Neurologic Impairment"],"prefix":"10.1542","volume":"137","author":[{"given":"Joanna","family":"Thomson","sequence":"first","affiliation":[{"name":"Divisions of Hospital Medicine,"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matt","family":"Hall","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital Association, Overland Park, Kansas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilliam","family":"Ambroggio","sequence":"additional","affiliation":[{"name":"Divisions of Hospital Medicine,"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio;"},{"name":"Biostatistics and Epidemiology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"Stone","sequence":"additional","affiliation":[{"name":"Primary Children\u2019s Medical Center, Intermountain Health Care, Salt Lake City, Utah;"},{"name":"Division of Inpatient Medicine, Department of Pediatrics, University of Utah, Salt Lake City, Utah;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajendu","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Primary Children\u2019s Medical Center, Intermountain Health Care, Salt Lake City, Utah;"},{"name":"Division of Inpatient Medicine, Department of Pediatrics, University of Utah, Salt Lake City, Utah;"},{"name":"Institute for Healthcare Delivery Research, Intermountain Healthcare, Salt Lake City, Utah;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir S.","family":"Shah","sequence":"additional","affiliation":[{"name":"Divisions of Hospital Medicine,"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio;"},{"name":"Infectious Diseases, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay G.","family":"Berry","sequence":"additional","affiliation":[{"name":"Division of General Pediatrics, Children\u2019s Hospital Boston, Boston, Massachusetts; 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