{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T11:22:04Z","timestamp":1793013724346,"version":"4.5.0"},"reference-count":27,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,6,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Infants &amp;lt;6 months old with influenza are at risk for adverse outcomes. Our objective was to compare influenza outcomes in infants &amp;lt;6 months old born to women who did and did not report influenza vaccine during pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>The study included all women who delivered from 12\/2005 to 3\/2014 at Intermountain facilities and their infants. Influenza outcomes included infant influenza-like illness (ILI), laboratory-confirmed influenza, and influenza hospitalizations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>The cohort included 245\u2009386 women and 249\u2009387 infants. Overall, 23\u2009383 (10%) pregnant women reported influenza immunization. This number increased from 2.2% before the H1N1 pandemic to 21% postpandemic (P &amp;lt; .001). A total of 866 infants &amp;lt;6 months old had \u22651 ILI encounter: 32 (1.34\/1000) infants born to women reporting immunization and 834 (3.70\/1000) born to women who did not report immunization (relative risk [RR] 0.36; 95% confidence interval [CI], 0.26\u20130.52; P &amp;lt; .001). A total of 658 infants had laboratory-confirmed influenza: 20 (0.84\/1000) born to women reporting immunization and 638 (2.83\/1000) born to unimmunized women (RR 0.30; 95% CI, 0.19\u20130.46; P &amp;lt; .001). A total of 151 infants with laboratory-confirmed influenza were hospitalized: 3 (0.13\/1000) born to women reporting immunization and 148 (0.66\/1000) born to unimmunized women (RR 0.19; 95% CI, 0.06\u20130.60; P = .005).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Self-reported influenza immunization during pregnancy was low but increased after the H1N1 pandemic. Infants born to women reporting influenza immunization during pregnancy had risk reductions of 64% for ILI, 70% for laboratory-confirmed influenza, and 81% for influenza hospitalizations in their first 6 months. Maternal influenza immunization during pregnancy is a public health priority.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1542\/peds.2015-2360","type":"journal-article","created":{"date-parts":[[2016,5,3]],"date-time":"2016-05-03T08:36:43Z","timestamp":1462264603000},"source":"Crossref","is-referenced-by-count":75,"title":["Influenza in Infants Born to Women Vaccinated During Pregnancy"],"prefix":"10.1542","volume":"137","author":[{"given":"Julie H.","family":"Shakib","sequence":"first","affiliation":[{"name":"Departments of Pediatrics, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent","family":"Korgenski","sequence":"additional","affiliation":[{"name":"Intermountain Healthcare, Salt Lake City, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela P.","family":"Presson","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Sheng","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"Varner","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew T.","family":"Pavia","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie L.","family":"Byington","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2016,6,1]]},"reference":[{"issue":"6","key":"2021120904495579300_B1","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1542\/peds.2006-1475","article-title":"Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection.","volume":"118","author":"Ampofo","year":"2006","journal-title":"Pediatrics"},{"issue":"22","key":"2021120904495579300_B2","first-page":"483","article-title":"Influenza activity: United States, 2013\u201314 season and composition of the 2014\u201315 influenza vaccines.","volume":"63","author":"Epperson","year":"2014","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"1","key":"2021120904495579300_B3","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1056\/NEJMoa054869","article-title":"The underrecognized burden of influenza in young children.","volume":"355","author":"Poehling","year":"2006","journal-title":"N Engl J Med"},{"issue":"2","key":"2021120904495579300_B4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1542\/peds.2012-1255","article-title":"The burden of influenza in young children, 2004\u20132009.","volume":"131","author":"Poehling","year":"2013","journal-title":"Pediatrics"},{"issue":"12","key":"2021120904495579300_B5","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/INF.0b013e3181b0c0ca","article-title":"Trivalent inactivated influenza virus vaccine given to two-month-old children: an off-season pilot study.","volume":"28","author":"Walter","year":"2009","journal-title":"Pediatr Infect Dis J"},{"issue":"10","key":"2021120904495579300_B6","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1086\/587643","article-title":"Safety and immunogenicity of trivalent inactivated influenza vaccine in infants.","volume":"197","author":"Halasa","year":"2008","journal-title":"J Infect Dis"},{"issue":"3","key":"2021120904495579300_B7","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.jpeds.2008.03.011","article-title":"Poor immune responses to a birth dose of diphtheria, tetanus, and acellular pertussis vaccine.","volume":"153","author":"Halasa","year":"2008","journal-title":"J Pediatr"},{"issue":"RR-07","key":"2021120904495579300_B8","first-page":"1","article-title":"Prevention and control of seasonal influenza with vaccines. 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