{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T14:19:38Z","timestamp":1782915578605,"version":"3.54.5"},"reference-count":25,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:sec>\n                  <jats:title>CONTEXT:<\/jats:title>\n                  <jats:p>Postoperative emesis is common after pyloromyotomy. Although postoperative feeding is likely to be an influencing factor, there is no consensus on optimal feeding.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>OBJECTIVE:<\/jats:title>\n                  <jats:p>To compare the effect of feeding regimens on clinical outcomes of infants after pyloromyotomy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>DATA SOURCES:<\/jats:title>\n                  <jats:p>Cumulative Index to Nursing and Allied Health Literature, The Cochrane Central Register of Controlled Trials, Embase, and Medline.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>STUDY SELECTION:<\/jats:title>\n                  <jats:p>Two reviewers independently assessed studies for inclusion based on a priori inclusion criteria.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>DATA EXTRACTION:<\/jats:title>\n                  <jats:p>Data were extracted on methodological quality, general study and intervention characteristics, and clinical outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>Fourteen studies were included. Ad libitum feeding was associated with significantly shorter length of stay (LOS) when compared with structured feeding (mean difference [MD] \u22124.66; 95% confidence interval [CI], \u22128.38 to \u22120.95; P = .01). Although gradual feeding significantly decreased emesis episodes (MD \u22121.70; 95% CI, \u22122.17 to \u22121.23; P &amp;lt; .00001), rapid feeding led to significantly shorter LOS (MD 22.05; 95% CI, 2.18 to 41.93; P = .03). Late feeding resulted in a significant decrease in number of patients with emesis (odds ratio 3.13; 95% CI, 2.26 to 4.35; P &amp;lt; .00001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>LIMITATIONS:<\/jats:title>\n                  <jats:p>Exclusion of non-English studies, lack of randomized controlled trials, insufficient number of studies to perform publication bias or subgroup analysis for potential predictors of emesis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Ad libitum feeding is recommended for patients after pyloromyotomy as it leads to decreased LOS. If physicians still prefer structured feeding, early rapid feeds are recommended as they should lead to a reduced LOS.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2015-2550","type":"journal-article","created":{"date-parts":[[2015,12,31]],"date-time":"2015-12-31T01:53:09Z","timestamp":1451526789000},"source":"Crossref","is-referenced-by-count":29,"title":["Feeding Post-Pyloromyotomy: A Meta-analysis"],"prefix":"10.1542","volume":"137","author":[{"given":"Katrina J.","family":"Sullivan","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s Hospital of Eastern Ontario, Ottawa, Ontario, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s Hospital of Eastern Ontario, Ottawa, Ontario, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Vincent","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s Hospital of Eastern Ontario, Ottawa, Ontario, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam","family":"Iqbal","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s Hospital of Eastern Ontario, Ottawa, Ontario, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Wayne","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s Hospital of Eastern Ontario, Ottawa, Ontario, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Nasr","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Children\u2019s Hospital of Eastern Ontario, Ottawa, Ontario, Canada; and"},{"name":"Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Canadian Association of Paediatric Surgeons Evidence-Based Resource","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2016,1,1]]},"reference":[{"issue":"2","key":"2021120907233743000_B1","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1089\/lap.2006.0143","article-title":"Ad libitum feeds after laparoscopic pyloromyotomy: a retrospective comparison with a standardized feeding regimen in 227 infants.","volume":"17","author":"Adibe","year":"2007","journal-title":"J Laparoendosc Adv Surg Tech A"},{"issue":"1","key":"2021120907233743000_B2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1055\/s-2001-12198","article-title":"An audit of post-pyloromyotomy feeding regimens.","volume":"11","author":"Lee","year":"2001","journal-title":"Eur J Pediatr Surg"},{"issue":"5","key":"2021120907233743000_B3","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1007\/s00464-003-9076-y","article-title":"Early feeding after laparoscopic pyloromyotomy: the pros and cons.","volume":"18","author":"van der Bilt","year":"2004","journal-title":"Surg Endosc"},{"issue":"11","key":"2021120907233743000_B4","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1016\/0022-3468(93)90435-N","article-title":"An analysis of feeding regimens after pyloromyotomy for hypertrophic pyloric stenosis.","volume":"28","author":"Georgeson","year":"1993","journal-title":"J Pediatr Surg"},{"issue":"6","key":"2021120907233743000_B5","first-page":"1133","article-title":"Gastric motility after pyloromyotomy in infants. 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