{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:29:04Z","timestamp":1790371744318,"version":"4.1.0"},"reference-count":21,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,5,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND:<\/jats:title>\n                  <jats:p>Transcutaneous bilirubin (TcB) meters are widely used for screening newborns for jaundice, with a total serum bilirubin (TSB) measurement indicated when the TcB value is classified as \u201cpositive\u201d by using a decision rule. The goal of our study was to assess the clinical utility of 3 recommended TcB screening decision rules.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>Paired TcB\/TSB measurements were collected at 34 newborn nursery sites. At 27 sites (sample 1), newborns were routinely screened with a TcB measurement. For sample 2, sites that typically screen with TSB levels also obtained a TcB measurement for the study. Three decision rules to define a positive TcB measurement were evaluated: \u226575th percentile on the Bhutani nomogram, 70% of the phototherapy level, and within 3 mg\/dL of the phototherapy threshold. The primary outcome was a TSB level at\/above the phototherapy threshold. The rate of false-negative TcB screens and percentage of blood draws avoided were calculated for each decision rule.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>For sample 1, data were analyzed on 911 paired TcB-TSB measurements from a total of 8316 TcB measurements. False-negative rates were &amp;lt;10% with all decision rules; none identified all 31 newborns with a TSB level at\/above the phototherapy threshold. The percentage of blood draws avoided ranged from 79.4% to 90.7%. In sample 2, each rule correctly identified all 8 newborns with TSB levels at\/above the phototherapy threshold.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Although all of the decision rules can be used effectively to screen newborns for jaundice, each will \u201cmiss\u201d some infants with a TSB level at\/above the phototherapy threshold.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2015-3032","type":"journal-article","created":{"date-parts":[[2016,4,6]],"date-time":"2016-04-06T15:38:29Z","timestamp":1459957109000},"source":"Crossref","is-referenced-by-count":14,"title":["Utility of Decision Rules for Transcutaneous Bilirubin Measurements"],"prefix":"10.1542","volume":"137","author":[{"given":"James A.","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Washington, Seattle, Washington;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony E.","family":"Burgos","sequence":"additional","affiliation":[{"name":"Kaiser Permanente, Downey, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Flaherman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California San Francisco, San Francisco, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther K.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Sidney Kimmel Medical College of Thomas Jefferson University and Nemours, Philadelphia, Pennsylvania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Simpson","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Mercy Hospital, Kansas City, Missouri;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neera K.","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Cincinnati Children\u2019s Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Von Kohorn","sequence":"additional","affiliation":[{"name":"Holy Cross Health, Silver Spring, Maryland; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niramol","family":"Dhepyasuwan","sequence":"additional","affiliation":[{"name":"Academic Pediatric Association, McLean, Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the BORN Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2016,5,1]]},"reference":[{"issue":"4","key":"2021120904325428000_B1","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1542\/peds.2009-0329","article-title":"Hyperbilirubinemia in the newborn infant &gt; or =35 weeks\u2019 gestation: an update with clarifications.","volume":"124","author":"Maisels","year":"2009","journal-title":"Pediatrics"},{"key":"2021120904325428000_B2","author":"Taylor","year":"2015"},{"issue":"1 pt 1","key":"2021120904325428000_B3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1542\/peds.110.1.61","article-title":"Assessment of a transcutaneous device in the evaluation of neonatal hyperbilirubinemia in a primarily Hispanic population.","volume":"110","author":"Engle","year":"2002","journal-title":"Pediatrics"},{"issue":"7","key":"2021120904325428000_B4","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/sj.jp.7211333","article-title":"Evaluation of a transcutaneous jaundice meter following hospital discharge in term and near-term neonates.","volume":"25","author":"Engle","year":"2005","journal-title":"J Perinatol"},{"issue":"2","key":"2021120904325428000_B5","doi-asserted-by":"crossref","DOI":"10.1542\/peds.106.2.e17","article-title":"Noninvasive measurement of total serum bilirubin in a multiracial predischarge newborn population to assess the risk of severe hyperbilirubinemia.","volume":"106","author":"Bhutani","year":"2000","journal-title":"Pediatrics"},{"issue":"2","key":"2021120904325428000_B6","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1651-2227.2002.tb01696.x","article-title":"A new transcutaneous bilirubinometer, BiliCheck, used in the neonatal intensive care unit and the maternity ward.","volume":"91","author":"Ebbesen","year":"2002","journal-title":"Acta Paediatr"},{"issue":"11","key":"2021120904325428000_B7","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1111\/j.1651-2227.2004.tb02634.x","article-title":"The value of Bilicheck as a screening tool for neonatal jaundice in term and near-term babies.","volume":"93","author":"Samanta","year":"2004","journal-title":"Acta Paediatr"},{"issue":"6","key":"2021120904325428000_B8","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1542\/peds.113.6.1628","article-title":"Evaluation of a new transcutaneous bilirubinometer.","volume":"113","author":"Maisels","year":"2004","journal-title":"Pediatrics"},{"issue":"10","key":"2021120904325428000_B9","first-page":"1193","article-title":"Noninvasive transcutaneous bilirubin as a screening test to identify the need for serum bilirubin assessment.","volume":"87","author":"Sanpavat","year":"2004","journal-title":"J Med Assoc Thai"},{"issue":"6","key":"2021120904325428000_B10","first-page":"1533","article-title":"Comparison of two transcutaneous bilirubinometers\u2014Minolta AirShields Jaundice Meter JM103 and Spectrx Bilicheck\u2013in Thai neonates.","volume":"36","author":"Sanpavat","year":"2005","journal-title":"Southeast Asian J Trop Med Public Health"},{"issue":"6","key":"2021120904325428000_B11","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1542\/peds.107.6.1264","article-title":"Transcutaneous bilirubin measurement: a multicenter evaluation of a new device.","volume":"107","author":"Rubaltelli","year":"2001","journal-title":"Pediatrics"},{"issue":"4","key":"2021120904325428000_B12","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1440-1754.2007.01062.x","article-title":"Prediction of severe hyperbilirubinaemia using the Bilicheck transcutaneous bilirubinometer.","volume":"43","author":"Boo","year":"2007","journal-title":"J Paediatr Child Health"},{"issue":"6","key":"2021120904325428000_B13","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1542\/peds.113.6.1636","article-title":"Transcutaneous bilirubin measurements and serum total bilirubin levels in indigenous African infants.","volume":"113","author":"Slusher","year":"2004","journal-title":"Pediatrics"},{"issue":"4","key":"2021120904325428000_B14","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1542\/peds.2005-0590","article-title":"Bilirubin measurement for neonates: comparison of 9 frequently used methods.","volume":"117","author":"Grohmann","year":"2006","journal-title":"Pediatrics"},{"issue":"6","key":"2021120904325428000_B15","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1001\/jama.1997.03540300056034","article-title":"Clinical prediction rules. 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