{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:19:24Z","timestamp":1790813964826,"version":"4.1.0"},"reference-count":36,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,6,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND AND OBJECTIVES:<\/jats:title>\n                  <jats:p>Neonatal outcomes vary by gestational age. We evaluated the association of early-term, full-term, and postterm birth with asphyxia, neurologic morbidity, and perinatal mortality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>Our register-based study used retrospective data on 214\u2009465 early-term (37+0\u201338+6 gestational weeks), 859\u2009827 full-term (39+0\u201341+6), and 55\u2009189 postterm (\u226542+0) live-born singletons during 1989\u20132008 in Finland. Asphyxia parameters were umbilical cord pH and Apgar score at 1 and 5 minutes. Neurologic morbidity outcome measures were cerebral palsy (CP), epilepsy, intellectual disability, and sensorineural defects diagnosed by the age of 4 years. Newborns with major congenital anomalies were excluded from perinatal deaths.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>Multivariate analysis showed that, compared with full-term pregnancies, early-term birth increased the risk for low Apgar score (&amp;lt;4) at 1 and 5 minutes (odds ratio 1.03, 95% confidence interval 1.03\u20131.04 and 1.24, 1.04\u20131.49, respectively), CP (1.40, 1.27\u20131.55), epilepsy (1.14, 1.06\u20131.23), intellectual disability (1.39, 1.27\u20131.53), sensorineural defects (1.24, 1.17\u20131.31), and perinatal mortality (2.40, 2.14\u20132.69), but risk for low umbilical artery pH \u22647.10 was decreased (0.83, 0.79\u20130.87). Postterm birth increased the risk for low Apgar score (&amp;lt;4) at 1 minute (1.26, 1.26\u20131.26) and 5 minutes (1.80, 1.43\u20132.34), low umbilical artery pH \u22647.10 (1.26, 1.19\u20131.34), and intellectual disability (1.19, 1.00\u20131.43), whereas risks for CP (1.03, 0.84\u20131.26), epilepsy (1.00, 0.87\u20131.15), sensorineural defects (0.96, 0.86\u20131.07), and perinatal mortality (0.91, 0.69\u20131.22) were not increased.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Early-term birth was associated with low Apgar score, increased neurologic morbidity, and perinatal mortality. Asphyxia and intellectual disability were more common among postterm births, but general neurologic morbidity and perinatal mortality were not increased.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2015-3334","type":"journal-article","created":{"date-parts":[[2016,5,27]],"date-time":"2016-05-27T12:14:11Z","timestamp":1464351251000},"source":"Crossref","is-referenced-by-count":59,"title":["Asphyxia, Neurologic Morbidity, and Perinatal Mortality in Early-Term and Postterm Birth"],"prefix":"10.1542","volume":"137","author":[{"given":"Laura","family":"Seikku","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Gissler","sequence":"additional","affiliation":[{"name":"Information Department, National Institute for Health and Welfare, Helsinki, Finland; and"},{"name":"Nordic School of Public Health, Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sture","family":"Andersson","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petri","family":"Rahkonen","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vedran","family":"Stefanovic","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minna","family":"Tikkanen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorma","family":"Paavonen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena","family":"Rahkonen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2016,6,1]]},"reference":[{"key":"2021120904515655700_B1","unstructured":"World Health Organization\n          . 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