{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:02:34Z","timestamp":1769040154565,"version":"3.49.0"},"reference-count":26,"publisher":"American Academy of Pediatrics (AAP)","issue":"Supplement_5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"abstract":"<jats:p>Autoimmune pancreatitis (AIP) is rare in teenagers and difficult to diagnose. There are no clear and established diagnostic criteria in the pediatric population to distinguish subtype 1 and subtype 2. Here, we report the case of a 16-year-old white French teenager admitted to the pediatric emergency service with more than 1 year\u2019s history of pain originating from the epigastric and the right hypochondriac regions, with bloody diarrhea. After exclusion of pancreatic cancer and other common causes of acute pancreatitis, the diagnosis of AIP was suspected. Biological analyses revealed acute pancreatitis with severe cholestasis and an elevated level of serum immunoglobulin G4. Magnetic resonance cholangiography revealed a voluminous pancreas presenting a typical \u201csausage-like\u201d aspect. Anatomopathological analyses of the liver biopsy specimen revealed a biliary obstruction due to pancreatic involvement without the typical aspect of chronic destructive cholangitis. Corticotherapy and immunosuppressive treatment proved effective after 1 week of treatment. Without a pancreatic biopsy specimen, the distinction between AIP type 1 and 2 could not be made clearly in this case. The succession of clinical observations could allow clinicians to recognize, treat, and manage AIP in children.<\/jats:p>","DOI":"10.1542\/peds.2016-0765","type":"journal-article","created":{"date-parts":[[2018,4,2]],"date-time":"2018-04-02T08:35:25Z","timestamp":1522658125000},"page":"S456-S461","source":"Crossref","is-referenced-by-count":6,"title":["Autoimmune Pancreatitis and Ulcerative Rectocolitis in an Adolescent"],"prefix":"10.1542","volume":"141","author":[{"given":"Elie","family":"Cousin","sequence":"first","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ianis","family":"Cousin","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Brest University Hospital, Brest, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Aziz","sequence":"additional","affiliation":[{"name":"Gastroenterology, Saint-Brieuc Hospital, Saint-Brieuc, France; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Chailloux","sequence":"additional","affiliation":[{"name":"Gastroenterology, Saint-Brieuc Hospital, Saint-Brieuc, France; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estelle","family":"Breton","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2018,4,1]]},"reference":[{"issue":"1","key":"2021121011400953200_B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1546-0096-9-1","article-title":"Successful treatment of pediatric IgG4 related systemic disease with mycophenolate mofetil: case report and a review of the pediatric autoimmune pancreatitis literature.","volume":"9","author":"Mannion","year":"2011","journal-title":"Pediatr Rheumatol Online J"},{"issue":"4","key":"2021121011400953200_B2","doi-asserted-by":"crossref","first-page":"e115","DOI":"10.14309\/crj.2016.88","article-title":"Autoimmune pancreatitis and IgG4 related disease in three children","volume":"3","author":"Bolia","year":"2016","journal-title":"ACG Case Rep J"},{"issue":"7","key":"2021121011400953200_B3","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/BF02285209","article-title":"Chronic pancreatitis caused by an autoimmune abnormality. 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