{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:22:17Z","timestamp":1770880937018,"version":"3.50.1"},"reference-count":16,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,12,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND AND OBJECTIVE:<\/jats:title>\n                  <jats:p>In July 2016, local transmission of Zika virus (ZIKV) was announced in Miami-Dade County, Florida. In this report, we describe the epidemiology of pediatric ZIKV infections in locally acquired and travel-associated cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>All children aged 1 to 17 years tested for ZIKV between October 1, 2015, and March 29, 2017, were included. SAS 9.4 was used to analyze age, sex, race and\/or ethnicity, origin of exposure, onset date, affiliation with a household cluster, clinical symptoms, hospitalizations, viremia, viruria, and antibody detection in specimens.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>Among 478 confirmed ZIKV cases in Miami-Dade County, 33 (6.9%) occurred in children (1\u201317 years). Twenty-seven (82.3%) cases were travel-associated. The median age of a pediatric Zika case patient was 11 years. Seventeen (51.5%) case patients were boys, and 23 (69.9%) were Hispanic. Among 31 symptomatic cases, all reported having rash, 25 (80.6%) reported fever, 9 (29.0%) reported conjunctivitis, and 7 (22.6%) reported arthralgia. Sixteen (48.5%) cases reported 2 of 4 and 8 (24.2%) reported 3 of 4 main symptoms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>This report found that the majority of children identified during the 2016 ZIKV outbreak only presented with 2 of the 4 main symptoms. In addition, pediatric ZIKV cases were frequently associated with symptomatic household members.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2017-2044","type":"journal-article","created":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T07:30:36Z","timestamp":1509521436000},"source":"Crossref","is-referenced-by-count":9,"title":["Epidemiology of Pediatric Zika Virus Infections"],"prefix":"10.1542","volume":"140","author":[{"given":"Isabel","family":"Griffin","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Cordero","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Logue","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen L.","family":"White","sequence":"additional","affiliation":[{"name":"Division of Disease Control and Health Protection, Bureau of Public Health Laboratories, Miami, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthoni","family":"Llau","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lakisha","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Noya-Chaveco","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Etienne","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mercedes","family":"Rojas","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Goldberg","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevie","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro","family":"Mejia-Echeverry","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edhelene","family":"Rico","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah D.","family":"Gillis","sequence":"additional","affiliation":[{"name":"Division of Disease Control and Health Protection, Bureau of Public Health Laboratories, Miami, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marshall","family":"Cone","sequence":"additional","affiliation":[{"name":"Division of Disease Control and Health Protection, Bureau of Public Health Laboratories, Miami, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reynald","family":"Jean","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lillian","family":"Rivera","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Disease Control, and Immunization Services, Florida Department of Health in Miami-Dade County, Miami, Florida; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2017,12,1]]},"reference":[{"issue":"16","key":"2021120916065072200_B1","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1056\/NEJMra1602113","article-title":"Zika virus.","volume":"374","author":"Petersen","year":"2016","journal-title":"N Engl J Med"},{"issue":"38","key":"2021120916065072200_B2","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.15585\/mmwr.mm6538e1","article-title":"Local mosquito-borne transmission of Zika virus - Miami-Dade and Broward counties, Florida, June-August 2016.","volume":"65","author":"Likos","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"24","key":"2021120916065072200_B3","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1056\/NEJMoa0805715","article-title":"Zika virus outbreak on Yap Island, Federated States of Micronesia.","volume":"360","author":"Duffy","year":"2009","journal-title":"N Engl J Med"},{"issue":"4","key":"2021120916065072200_B4","doi-asserted-by":"crossref","first-page":"e0004636","DOI":"10.1371\/journal.pntd.0004636","article-title":"Zika virus outbreak in Rio de Janeiro, Brazil: clinical characterization, epidemiological and virological aspects.","volume":"10","author":"Brasil","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"44","key":"2021120916065072200_B5","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.15585\/mmwr.mm6544a4","article-title":"Incidence of Zika virus disease by age and sex - Puerto Rico, November 1, 2015-October 20, 2016.","volume":"65","author":"Lozier","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"5","key":"2021120916065072200_B6","doi-asserted-by":"crossref","first-page":"841","DOI":"10.3201\/eid2305.161715","article-title":"Estimated incubation period for Zika virus disease.","volume":"23","author":"Krow-Lucal","year":"2017","journal-title":"Emerg Infect Dis"},{"issue":"5","key":"2021120916065072200_B7","doi-asserted-by":"crossref","first-page":"e20160621","DOI":"10.1542\/peds.2016-0621","article-title":"Zika virus disease: a CDC update for pediatric health care providers.","volume":"137","author":"Karwowski","year":"2016","journal-title":"Pediatrics"},{"issue":"39","key":"2021120916065072200_B8","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.15585\/mmwr.mm6539e2","article-title":"Characteristics of children aged &lt;18 years with Zika virus disease acquired postnatally\u2013U.S. States, January 2015-July 2016.","volume":"65","author":"Goodman","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"4","key":"2021120916065072200_B9","doi-asserted-by":"crossref","first-page":"669","DOI":"10.3201\/eid2304.161549","article-title":"Zika virus seroprevalence, French Polynesia, 2014-2015.","volume":"23","author":"Aubry","year":"2017","journal-title":"Emerg Infect Dis"},{"key":"2021120916065072200_B10","unstructured":"Centers for Disease Control and Prevention\n          . CDC Zika interim response plan. 2017. Available at: https:\/\/www.cdc.gov\/zika\/pdfs\/Zika-Draft-Interim-CONUS-Plan.pdf. Accessed May 8, 2017"},{"key":"2021120916065072200_B11","unstructured":"Centers for Disease Control and Prevention\n          . Zika virus disease and Zika virus infection 2016 case definition. 2016. Available at: https:\/\/wwwn.cdc.gov\/nndss\/conditions\/zika\/case-definition\/2016\/06\/. Accessed May 8, 2017"},{"key":"2021120916065072200_B12","unstructured":"Florida Department of Health\n          . Zika fever: information for clinicians. Version 3.0. Available at: http:\/\/www.floridahealth.gov\/diseases-and-conditions\/zika-virus\/_documents\/clinician-one-v3.pdf. 2016. Accessed August 23, 2017"},{"issue":"18","key":"2021120916065072200_B13","doi-asserted-by":"crossref","first-page":"475","DOI":"10.15585\/mmwr.mm6518e2","article-title":"Comparison of test results for Zika virus RNA in urine, serum, and saliva specimens from persons with travel-associated Zika virus disease\u2014Florida, 2016.","volume":"65","author":"Bingham","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2021120916065072200_B14","unstructured":"Centers for Disease Control and Prevention\n          . Diagnostic tests for Zika virus. 2017. Available at: https:\/\/www.cdc.gov\/zika\/hc-providers\/types-of-tests.html. Accessed May 3, 2017"},{"issue":"4","key":"2021120916065072200_B15","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/AOG.0000000000001625","article-title":"Prolonged detection of Zika virus RNA in pregnant women.","volume":"128","author":"Meaney-Delman","year":"2016","journal-title":"Obstet Gynecol"},{"key":"2021120916065072200_B16","unstructured":"US Census Bureau\n          . 2010-2014 American community survey 5-year estimates. Available at: https:\/\/factfinder.census.gov\/faces\/tableservices\/jsf\/pages\/productview.xhtml?src=bkmk. Accessed August 16, 2017"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2017-2044\/914388\/peds_20172044.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2017-2044\/914388\/peds_20172044.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T04:16:06Z","timestamp":1639109766000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/140\/6\/e20172044\/38174\/Epidemiology-of-Pediatric-Zika-Virus-Infections"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,1]]},"references-count":16,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,12,1]]},"published-print":{"date-parts":[[2017,12,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2017-2044","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,1]]},"article-number":"e20172044"}}