{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:57:48Z","timestamp":1790675868506,"version":"4.1.0"},"reference-count":61,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND:<\/jats:title>\n                  <jats:p>Young adults living with perinatally acquired HIV infection (PHIVYAs) are at risk for poor biomedical and behavioral health outcomes. Few studies offer a comprehensive overview of the functioning of this population in young adulthood and the role of HIV.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>Data come from the Child and Adolescent Self-Awareness and Health Study, a longitudinal behavioral health cohort study of PHIVYAs and perinatally HIV\u2013exposed but uninfected young adults (PHEUYAs) who are compared on psychiatric and neurocognitive functioning, sexual and substance use behaviors, health and reproductive outcomes, and young adult milestones.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>Overall, 27% of participants met criteria for a psychiatric disorder, including mood (11%), anxiety (22%), and substance use (28%), with no HIV status differences. PHIVYAs performed worse on 2 neurocognitive tests. There were no HIV status differences in condomless sex (41%) or pregnancies (41% women; 38% men). Both groups exhibited similar adult milestones: 67% graduated high school or an equivalent, 19% were in college, and 42% were employed. However, 38% were neither in school or working, 12% reported incarceration, and 16% were ever homeless. Among PHIVYAs, 36% were viremic (&amp;gt;200 copies per mL), and 15% were severely immunocompromised (CD4+ cell count &amp;lt;100 cells per mm3).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>Many PHIVYAs achieve adult milestones related to school, employment, sexual relationships, and starting families. However, they and PHEUYAs have high rates of psychiatric and substance use disorders and behavioral risks, which can jeopardize long-term health and adult functioning, particularly in the context of HIV. These findings underscore an urgent need to escalate interventions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2018-0938","type":"journal-article","created":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T07:25:12Z","timestamp":1533885912000},"source":"Crossref","is-referenced-by-count":54,"title":["Behavioral Health and Adult Milestones in Young Adults With Perinatal HIV Infection or Exposure"],"prefix":"10.1542","volume":"142","author":[{"given":"Elaine J.","family":"Abrams","sequence":"first","affiliation":[{"name":"ICAP at Columbia University, Mailman School of Public Health,"},{"name":"Vagelos College of Physicians and Surgeons, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude A.","family":"Mellins","sequence":"additional","affiliation":[{"name":"HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia","family":"Bucek","sequence":"additional","affiliation":[{"name":"HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis","family":"Dolezal","sequence":"additional","affiliation":[{"name":"HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeannette","family":"Raymond","sequence":"additional","affiliation":[{"name":"HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Wiznia","sequence":"additional","affiliation":[{"name":"Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Jurgrau","sequence":"additional","affiliation":[{"name":"New York\u2013Presbyterian Hospital\/Columbia University Medical Center, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahrukh","family":"Bamji","sequence":"additional","affiliation":[{"name":"Metropolitan Hospital Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Shiun","family":"Leu","sequence":"additional","affiliation":[{"name":"HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiu Kee Warren","family":"Ng","sequence":"additional","affiliation":[{"name":"New York\u2013Presbyterian Hospital\/Columbia University Medical Center, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2018,9,1]]},"reference":[{"issue":"5","key":"2021120916234973200_B1","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/COH.0b013e328363d280","article-title":"Prevention of mother-to-child HIV transmission: can we meet the goal of global elimination of new pediatric infections?","volume":"8","author":"Mofenson","year":"2013","journal-title":"Curr Opin HIV AIDS"},{"issue":"5","key":"2021120916234973200_B2","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1001\/jamapediatrics.2016.5053","article-title":"Estimated perinatal HIV infection among infants born in the United States, 2002-2013.","volume":"171","author":"Taylor","year":"2017","journal-title":"JAMA Pediatr"},{"key":"2021120916234973200_B3","unstructured":"Centers for Disease Control and Prevention. 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