{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T06:05:00Z","timestamp":1778565900037,"version":"3.51.4"},"reference-count":16,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,1]]},"abstract":"<jats:p>Naphthalene poisoning due to exposure to mothballs is a common cause of toxicity in children worldwide. Naphthalene toxicity is known to cause hemolytic anemia, methemoglobinemia, and hepatic and renal injury. Neonates are more susceptible to the effects of oxidative stress from naphthalene because of their low glutathione stores and immaturity of hepatic enzymes. However, there are no reported cases of chronic fetal exposure to naphthalene during pregnancy. We report a novel case of chronic fetal exposure to naphthalene-containing mothballs that occurred from the second trimester through the third trimester of pregnancy. Our patient presented with hyperbilirubinemia, requiring exchange transfusion, severe hemolytic anemia, pulmonary hypertension, respiratory failure, and renal failure and progressed to develop \u201cbronze baby\u201d syndrome. Pregnant mothers should be diligently screened for such exposures and if found should receive psychiatric evaluation and counseling to prevent such devastating effects in neonates.<\/jats:p>","DOI":"10.1542\/peds.2018-3619","type":"journal-article","created":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T17:25:32Z","timestamp":1557249932000},"source":"Crossref","is-referenced-by-count":9,"title":["Newborn Infant With Mothball Toxicity Due to Maternal Ingestion"],"prefix":"10.1542","volume":"143","author":[{"given":"Mitali","family":"Sahni","sequence":"first","affiliation":[{"name":"Division of Neonatology, St Christopher\u2019s Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanick","family":"Vibert","sequence":"additional","affiliation":[{"name":"Division of Neonatology, St Christopher\u2019s Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vineet","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Division of Neonatology, St Christopher\u2019s Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ogechukwu","family":"Menkiti","sequence":"additional","affiliation":[{"name":"Division of Neonatology, St Christopher\u2019s Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2019,6,1]]},"reference":[{"issue":"10","key":"2021120913200344500_B1","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1080\/15563650.2017.1388087","article-title":"2016 Annual Report of the American Association of Poison Control Centers\u2019 National Poison Data System (NPDS): 34th Annual Report.","volume":"55","author":"Gummin","year":"2017","journal-title":"Clin Toxicol (Phila)"},{"issue":"10","key":"2021120913200344500_B2","doi-asserted-by":"crossref","first-page":"949","DOI":"10.3109\/15563650.2013.863906","article-title":"2012 Annual Report of the American Association of Poison Control Centers\u2019 National Poison Data System (NPDS): 30th Annual Report.","volume":"51","author":"Mowry","year":"2013","journal-title":"Clin Toxicol (Phila)"},{"issue":"10","key":"2021120913200344500_B3","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.3109\/15563650.2014.987397","article-title":"2013 Annual Report of the American Association of Poison Control Centers\u2019 National Poison Data System (NPDS): 31st Annual Report.","volume":"52","author":"Mowry","year":"2014","journal-title":"Clin Toxicol (Phila)"},{"issue":"2","key":"2021120913200344500_B4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0031-3955(16)35007-6","article-title":"Mothball toxicity.","volume":"33","author":"Siegel","year":"1986","journal-title":"Pediatr Clin North Am"},{"issue":"12","key":"2021120913200344500_B5","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/sj.jp.7211195","article-title":"Perinatal toxicity of domestic naphthalene exposure.","volume":"24","author":"Molloy","year":"2004","journal-title":"J Perinatol"},{"key":"2021120913200344500_B6","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/S0022-3476(63)80221-8","article-title":"Acute hemolysis due to naphthalene inhalation.","volume":"63","author":"Valaes","year":"1963","journal-title":"J Pediatr"},{"key":"2021120913200344500_B7","first-page":"1958","volume-title":"Goldfrank\u2019s Toxicologic Emergencies","author":"Nelson","year":"2006","edition":"9th ed."},{"key":"2021120913200344500_B8","first-page":"13","article-title":"Naphthalene mothballs: emerging and recurring issues and their relevance to environmental health.","volume":"7","author":"Sudakin","year":"2011","journal-title":"Curr Top Toxicol"},{"issue":"5","key":"2021120913200344500_B9","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1542\/peds.7.5.722","article-title":"Acute hemolytic anemia due to ingestion of naphthalene moth balls. 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