{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:00:14Z","timestamp":1780462814496,"version":"3.54.1"},"reference-count":52,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11,1]]},"abstract":"\n OBJECTIVE:<\/jats:title>\n To evaluate the effect of vaccine hesitancy screening on childhood vaccine uptake.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n We conducted a cluster randomized controlled trial in pediatric primary care clinics in Washington state. Vaccine-hesitant parents (VHPs) with a healthy newborn receiving health supervision at participating clinics were eligible. VHPs were identified by using a 4-item version of the validated Parent Attitudes About Childhood Vaccines Survey (PACV). Before their child\u2019s 2- and 6-month health supervision visits, VHPs at intervention clinics completed the 15-item PACV embedded in a survey containing placebo items. Intervention providers received a summary of parents\u2019 15-item PACV responses and interpretation of their PACV score; discretion was given to providers regarding how they acted on this information. VHPs at control clinics completed only the placebo survey items, and their child\u2019s provider received a summary of their responses; control providers remained blinded to parent VHP status. Our outcome was child immunization status at 8 months of age expressed as percent of days underimmunized. We compared outcomes in control and intervention participants using t test and linear mixed-effects regression.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n We enrolled 24 clinics (12 in each arm) and 156 parents (65 in the intervention arm). Parent characteristics were similar across arms except more intervention (versus control) parents had a first-born child (60.9% vs 44%; P = .04). No significant difference in outcome was detected between arms (25.2% [95% confidence interval: 16.0% to 34.5%] vs 19.1% [95% confidence interval: 12.0% to 26.3%] mean days underimmunized in the intervention and control arms, respectively).<\/jats:p>\n <\/jats:sec>\n \n CONCLUSION:<\/jats:title>\n Vaccine hesitancy screening was not significantly associated with days underimmunized.<\/jats:p>\n <\/jats:sec>","DOI":"10.1542\/peds.2019-0802","type":"journal-article","created":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T12:25:13Z","timestamp":1570623913000},"source":"Crossref","is-referenced-by-count":26,"title":["Previsit Screening for Parental Vaccine Hesitancy: A Cluster Randomized Trial"],"prefix":"10.1542","volume":"144","author":[{"given":"Douglas J.","family":"Opel","sequence":"first","affiliation":[{"name":"Seattle Children\u2019s Research Institute, Seattle, Washington;"},{"name":"Department of Pediatrics, School of Medicine, University of Washington, Seattle, Washington; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Henrikson","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Lepere","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Research Institute, Seattle, Washington;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene","family":"Hawkes","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Seattle Children\u2019s Research Institute, Seattle, Washington;"},{"name":"Department of Pediatrics, School of Medicine, University of Washington, Seattle, Washington; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Dunn","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine, University of Washington, Seattle, Washington; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2019,11,1]]},"reference":[{"issue":"4","key":"2021121109153785800_B1","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1542\/peds.2007-0538","article-title":"Parents with doubts about vaccines: which vaccines and reasons 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