{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T11:19:36Z","timestamp":1784027976664,"version":"3.55.0"},"reference-count":18,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND:<\/jats:title>\n                  <jats:p>Premature infants have bradycardia and\/or desaturation events due to apnea of prematurity that resolve as the infants mature. Despite American Academy of Pediatrics guidelines recommending a standard \u201cevent-free\u201d period before discharge, length of observation in our Intensive Care Nursery was variable. By June 2018, for infants born &amp;lt;36 weeks\u2019 gestation in the Intensive Care Nursery, we aimed to standardize time to discharge after the last documented event at 5 days, when the baseline mean was 3.6 days (range 0\u20136 days).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>A quality-improvement team used the Model for Improvement. Plan-do-study-act cycles improved nursing documentation of events and standardized discharge criteria after consensus on operational definitions. The outcome measure was days to discharge after last documented event. Process measures included percentage of events documented completely and correctly in the electronic medical record. Balancing measure was length of stay after 36 weeks\u2019 corrected gestational age. We used statistical process control.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>The baseline event watch ranged from 0 to 6 days. After defining significant events, documentation expectations, and consensus on a 5-day \u201cwatch\u201d before discharge, the event watch range narrowed with a mean that shifted from 3.6 to 4.8 days on X-bar S statistical process control chart. Completeness of documentation increased from 38% to 63%, and documentation of significant events increased from 38% to 88%. Length of stay after 36 weeks\u2019 corrected gestational age was unchanged, and nursing satisfaction improved.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>We found decreasing variation in the management of apnea of prematurity while simultaneously improving staff satisfaction. Next steps include revising electronic medical record flowsheets and spread to network NICUs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.2019-0861","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T13:25:13Z","timestamp":1579094713000},"source":"Crossref","is-referenced-by-count":10,"title":["Reducing Variation in the Management of Apnea of Prematurity in the Intensive Care Nursery"],"prefix":"10.1542","volume":"145","author":[{"given":"Katherine","family":"Coughlin","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania; and Penn Neonatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Posencheg","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania; and Penn Neonatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Orfe","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania; and Penn Neonatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whitney","family":"Zachritz","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania; and Penn Neonatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaqueline","family":"Meadow","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania; and Penn Neonatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kesi","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania; and Penn Neonatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori","family":"Christ","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania; and Penn Neonatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2020,2,1]]},"reference":[{"issue":"1","key":"2021120819580853300_B1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1088\/0967-3334\/33\/1\/1","article-title":"A new algorithm for detecting central apnea in neonates","volume":"33","author":"Lee","year":"2012","journal-title":"Physiol Meas"},{"issue":"3, pt 2","key":"2021120819580853300_B2","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1542\/peds.2005-0620H","article-title":"Summary proceedings from the apnea-of-prematurity group","volume":"117","author":"Finer","year":"2006","journal-title":"Pediatrics"},{"issue":"2","key":"2021120819580853300_B3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S1084-2756(02)00219-1","article-title":"Early NICU discharge of very low birth weight infants: a critical review and analysis","volume":"8","author":"Merritt","year":"2003","journal-title":"Semin Neonatol"},{"issue":"2","key":"2021120819580853300_B4","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2010-1567","article-title":"Epidemiology of apnea and bradycardia resolution in premature infants","volume":"128","author":"Lorch","year":"2011","journal-title":"Pediatrics"},{"issue":"12","key":"2021120819580853300_B5","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/sj.jp.7211182","article-title":"Apnea is associated with neurodevelopmental impairment in very low birth weight infants","volume":"24","author":"Janvier","year":"2004","journal-title":"J Perinatol"},{"issue":"3","key":"2021120819580853300_B6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1159\/000097446","article-title":"Factors influencing apnea and bradycardia of prematurity - implications for neurodevelopment","volume":"91","author":"Pillekamp","year":"2007","journal-title":"Neonatology"},{"issue":"1","key":"2021120819580853300_B7","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2010-0495","article-title":"Variation in diagnosis of apnea in moderately preterm infants predicts length of stay","volume":"127","author":"Eichenwald","year":"2011","journal-title":"Pediatrics"},{"issue":"1","key":"2021120819580853300_B8","doi-asserted-by":"crossref","first-page":"e20153757","DOI":"10.1542\/peds.2015-3757","article-title":"Apnea of prematurity","volume":"137","author":"Eichenwald","year":"2016","journal-title":"Pediatrics"},{"issue":"2","key":"2021120819580853300_B9","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2013a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"issue":"2","key":"2021120819580853300_B10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/jp.2015.167","article-title":"Apnea of prematurity and caffeine pharmacokinetics: potential impact on hospital discharge","volume":"36","author":"Doyle","year":"2016","journal-title":"J Perinatol"},{"key":"2021120819580853300_B11","volume-title":"The Health Care Data Guide: Learning from Data for Improvement","author":"Provost","year":"2011"},{"issue":"6","key":"2021120819580853300_B12","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1136\/qhc.12.6.458","article-title":"Statistical process control as a tool for research and healthcare improvement","volume":"12","author":"Benneyan","year":"2003","journal-title":"Qual Saf Health Care"},{"issue":"12","key":"2021120819580853300_B13","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1136\/bmjqs-2015-004411","article-title":"SQUIRE 2.0 (Standards for Quality Improvement Reporting Excellence): revised publication guidelines from a detailed consensus process","volume":"25","author":"Ogrinc","year":"2016","journal-title":"BMJ Qual Saf"},{"issue":"24","key":"2021120819580853300_B14","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1001\/jama.2008.846","article-title":"Physician autonomy and informed decision making: finding the balance for patient safety and quality","volume":"300","author":"Mathews","year":"2008","journal-title":"JAMA"},{"issue":"6","key":"2021120819580853300_B15","first-page":"263","article-title":"Standardizing documentation and the clinical approach to apnea of prematurity reduces length of stay, improves staff satisfaction, and decreases hospital cost","volume":"40","author":"Butler","year":"2014","journal-title":"Jt Comm J Qual Patient Saf"},{"issue":"1","key":"2021120819580853300_B16","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1542\/peds.111.1.146","article-title":"Cost-effectiveness analysis of predischarge monitoring for apnea of prematurity","volume":"111","author":"Zupancic","year":"2003","journal-title":"Pediatrics"},{"issue":"1","key":"2021120819580853300_B17","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/jp.2016.167","article-title":"Clinically significant cardiopulmonary events and the effect of definition standardization on apnea of prematurity management","volume":"37","author":"Powell","year":"2017","journal-title":"J Perinatol"},{"issue":"1","key":"2021120819580853300_B18","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/jp.2017.174","article-title":"Apnea, bradycardia and desaturation spells in premature infants: impact of a protocol for the duration of \u2018spell-free\u2019 observation on interprovider variability and readmission rates","volume":"38","author":"Chandrasekharan","year":"2018","journal-title":"J Perinatol"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-0861\/1078961\/peds_20190861.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-0861\/1078961\/peds_20190861.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T23:10:33Z","timestamp":1639005033000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/145\/2\/e20190861\/68275\/Reducing-Variation-in-the-Management-of-Apnea-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,1]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2,1]]},"published-print":{"date-parts":[[2020,2,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2019-0861","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,1]]},"article-number":"e20190861"}}