{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:59:16Z","timestamp":1753887556210,"version":"3.41.2"},"reference-count":7,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,1]]},"abstract":"<jats:p>Eosinophilic gastrointestinal diseases (EGIDs) are a diverse group of intestinal diseases involving the infiltration of eosinophils into the bowel wall. EGID can present with a variety of clinical conditions, which are largely dependent on the location of eosinophils in the intestinal wall. We describe the first reported pediatric cases of EGID presenting with symptomatic partial bowel obstruction from intestinal masses due to isolated focal mural involvement. Both patients subsequently responded favorably to therapy with exclusive elemental nutrition in the first case and exclusive elemental nutrition with steroids in the second case. These cases reveal the wide-ranging clinical manifestations of EGID, expand on the differential diagnosis of focal intestinal masses, and provide guidance on the evaluation of ambiguous cases.<\/jats:p>","DOI":"10.1542\/peds.2019-1610","type":"journal-article","created":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T13:24:23Z","timestamp":1582118663000},"source":"Crossref","is-referenced-by-count":1,"title":["Mural Eosinophilic Gastrointestinal Disease in 2 Pediatric Patients Presenting as Focal Mass"],"prefix":"10.1542","volume":"145","author":[{"given":"Alexa","family":"Manrriquez","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Hospital Los Angeles, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Alharbi","sequence":"additional","affiliation":[{"name":"Divisions of Gastroenterology, Hepatology and Nutrition and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda","family":"Braskett","sequence":"additional","affiliation":[{"name":"Clinical Immunology and Allergy and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vrinda","family":"Bhardwaj","sequence":"additional","affiliation":[{"name":"Divisions of Gastroenterology, Hepatology and Nutrition and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2020,3,1]]},"reference":[{"issue":"2","key":"2021121013090940800_B1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.anai.2018.06.013","article-title":"Eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis","volume":"121","author":"Egan","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"key":"2021121013090940800_B2","doi-asserted-by":"crossref","first-page":"463689","DOI":"10.5402\/2012\/463689","article-title":"Eosinophilic gastrointestinal diseases: review and update","volume":"2012","author":"Jawairia","year":"2012","journal-title":"ISRN Gastroenterol"},{"issue":"5","key":"2021121013090940800_B3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/PAP.0b013e318229bfe2","article-title":"Histopathologic diagnosis of eosinophilic conditions in the gastrointestinal tract","volume":"18","author":"Hurrell","year":"2011","journal-title":"Adv Anat Pathol"},{"issue":"4","key":"2021121013090940800_B4","doi-asserted-by":"crossref","first-page":"W18","DOI":"10.1308\/147870810X12659688851915","article-title":"Transmural eosinophilic gastritis with gastric outlet obstruction: case report and review of the literature","volume":"92","author":"Holroyd","year":"2010","journal-title":"Ann R Coll Surg Engl"},{"issue":"2","key":"2021121013090940800_B5","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.gtc.2014.02.007","article-title":"Histopathologic features of eosinophilic esophagitis and eosinophilic gastrointestinal diseases","volume":"43","author":"Collins","year":"2014","journal-title":"Gastroenterol Clin North Am"},{"key":"2021121013090940800_B6","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3389\/fmed.2017.00261","article-title":"Eosinophilic gastrointestinal disorders pathology","volume":"4","author":"Collins","year":"2018","journal-title":"Front Med (Lausanne)"},{"key":"2021121013090940800_B7","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1186\/s40064-015-1157-6","article-title":"Chronic ileocolic intussusception due to transmural infiltration of diffuse large B cell lymphoma in a 14-year-old boy: a case report","volume":"4","author":"Saka","year":"2015","journal-title":"Springerplus"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-1610\/1079186\/peds_20191610.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-1610\/1079186\/peds_20191610.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T04:45:26Z","timestamp":1695789926000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/145\/3\/e20191610\/36812\/Mural-Eosinophilic-Gastrointestinal-Disease-in-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,1]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,3,1]]},"published-print":{"date-parts":[[2020,3,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2019-1610","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"type":"print","value":"0031-4005"},{"type":"electronic","value":"1098-4275"}],"subject":[],"published":{"date-parts":[[2020,3,1]]},"article-number":"e20191610"}}