{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:15:08Z","timestamp":1787022908734,"version":"build-2736575974"},"reference-count":8,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,1]]},"abstract":"<jats:p>Electronic cigarette or vaping product use\u2013associated lung injury (EVALI) is a newly emerging diagnosis in the United States, yet the incidence has surged greatly in the past year. With the trend of using electronic cigarettes (e-cigarettes) and vaping rising at an alarming rate among teenagers, many are resorting to friends, illicit drug dealers, and other informal sources to obtain their e-cigarettes, which is greatly contributing to the national outbreak of EVALI. The incidence of adolescents presenting with the constellation of respiratory, gastrointestinal, and constitutional symptoms characteristic of EVALI has been widely reported within the nation. We present one such case of an adolescent boy with a 2-year history of daily vaping who presented with nausea, vomiting, weight loss, and fever but lacked the respiratory symptoms that have been reported in the majority of EVALI cases reported thus far. Computed tomography scan of the abdomen and pelvis revealed an incidental finding of lung pathology characteristic of EVALI, prompting further workup and diagnosis of EVALI. In this case, it is demonstrated that the presentation of EVALI can be variable and is still poorly defined. The rising morbidity and mortality from EVALI reveal the importance of considering EVALI in all patients with a history of vaping or e-cigarette use, regardless of the presence or absence of respiratory symptoms.<\/jats:p>","DOI":"10.1542\/peds.2019-3408","type":"journal-article","created":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T08:25:14Z","timestamp":1587457514000},"source":"Crossref","is-referenced-by-count":24,"title":["E-cigarette or Vaping Product Use\u2013Associated Lung Injury (EVALI) Without Respiratory Symptoms"],"prefix":"10.1542","volume":"145","author":[{"given":"Praneeja","family":"Matta","sequence":"first","affiliation":[{"name":"Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacquelyn N.","family":"Hamati","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayato L.","family":"Unno","sequence":"additional","affiliation":[{"name":"Pediatric Residency Program and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Fox","sequence":"additional","affiliation":[{"name":"Department of Pediatrics,"},{"name":"Diagnostic Referral Division, Nemours\/Alfred I. duPont Hospital for Children, Wilmington, Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2020,5,1]]},"reference":[{"issue":"4","key":"2021121117165180500_B1","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1080\/02739615.2016.1227937","article-title":"A qualitative study of adolescent perceptions of electronic cigarettes and their marketing: implications for prevention and policy","volume":"46","author":"Johnson","year":"2017","journal-title":"Child Health Care"},{"issue":"2","key":"2021121117165180500_B2","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1136\/tobaccocontrol-2018-054382","article-title":"Vaping versus JUULing: how the extraordinary growth and marketing of JUUL transformed the US retail e-cigarette market","volume":"28","author":"Huang","year":"2019","journal-title":"Tob Control"},{"key":"2021121117165180500_B3","volume-title":"E-Cigarette Use Among Youth and Young Adults. A Report of the Surgeon General","author":"US Department of Health and Human Services","year":"2016"},{"key":"2021121117165180500_B4","unstructured":"CDC. Outbreak of lung injury associated with the use of e-cigarette, or vaping, products.\u20082019. Available at: https:\/\/www.cdc.gov\/tobacco\/basic_information\/e-cigarettes\/severe-lung-disease.html. Accessed September 25, 2019"},{"key":"2021121117165180500_B5","unstructured":"CDC. New CDC report provides first analysis of lung injury deaths associated with use of e-cigarette, or vaping, products.\u20082019. Available at: https:\/\/www.cdc.gov\/media\/releases\/2019\/p1028-first-analysis-lung-injury-deaths.html. Accessed September 25, 2019"},{"key":"2021121117165180500_B6","unstructured":"Farkas\u2008J. Vaping associated pulmonary injury (VAPI). Available at: https:\/\/emcrit.org\/ibcc\/vaping-associated-pulmonary-injury\/. Accessed September 25, 2019"},{"issue":"10","key":"2021121117165180500_B7","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1056\/NEJMoa1911614","article-title":"Pulmonary illness related to e-cigarette use in Illinois and Wisconsin - final report","volume":"382","author":"Layden","year":"2020","journal-title":"N Engl J Med"},{"issue":"15","key":"2021121117165180500_B8","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1056\/NEJMc1912038","article-title":"Pulmonary lipid-laden macrophages and vaping","volume":"381","author":"Maddock","year":"2019","journal-title":"N Engl J Med"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-3408\/1079209\/peds_20193408.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-3408\/1079209\/peds_20193408.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T12:17:07Z","timestamp":1639225027000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/145\/5\/e20193408\/36780\/E-cigarette-or-Vaping-Product-Use-Associated-Lung"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,1]]},"references-count":8,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,5,1]]},"published-print":{"date-parts":[[2020,5,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2019-3408","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,1]]},"article-number":"e20193408"}}