{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T13:11:45Z","timestamp":1774530705264,"version":"3.50.1"},"reference-count":13,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:p>A previously healthy 15-year-old boy presented with 3 months of progressive psychosis, insomnia, back and groin pain, and hyperhidrosis. On examination, the patient was disheveled, agitated, and soaked with sweat, with systolic blood pressure in the 160s and heart rate in the 130s. Aside from occasional auditory and visual hallucinations, his neurologic examination was normal. The patient was admitted for an extensive workup, including MRI of the brain and spine and lumbar puncture, which were normal. Through collaboration with various pediatric specialists, including psychiatry and neurology, a rare diagnosis was ultimately unveiled.<\/jats:p>","DOI":"10.1542\/peds.2019-3786","type":"journal-article","created":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T12:25:22Z","timestamp":1590150322000},"source":"Crossref","is-referenced-by-count":4,"title":["A Previously Healthy Adolescent With Acute Psychosis and Severe Hyperhidrosis"],"prefix":"10.1542","volume":"145","author":[{"given":"Tatiana","family":"Rosenblatt","sequence":"first","affiliation":[{"name":"Stanford University School of Medicine and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Ort","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine and"},{"name":"Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Shaw","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine and"},{"name":"Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca J.","family":"Levy","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine and"},{"name":"Division of Child Neurology, Department of Neurology and Neurological Sciences, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine and"},{"name":"Division of Pediatric Hospital Medicine, Department of Pediatrics, Stanford University, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Niemi","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Hoang","sequence":"additional","affiliation":[{"name":"Stanford University School of Medicine and"},{"name":"Division of Pediatric Hospital Medicine, Department of Pediatrics, Stanford University, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2020,6,1]]},"reference":[{"issue":"5","key":"2021121014050333400_B1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/modpathol.2012.207","article-title":"Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies","volume":"26","author":"Larsen","year":"2013","journal-title":"Mod Pathol"},{"issue":"9","key":"2021121014050333400_B2","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1097\/PSY.0b013e3181572799","article-title":"Psychiatric medications for the treatment of pruritus","volume":"69","author":"Shaw","year":"2007","journal-title":"Psychosom Med"},{"issue":"4","key":"2021121014050333400_B3","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S1474-4422(15)00401-9","article-title":"A clinical approach to diagnosis of autoimmune encephalitis","volume":"15","author":"Graus","year":"2016","journal-title":"Lancet Neurol"},{"issue":"1","key":"2021121014050333400_B4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1089\/cap.2014.0084","article-title":"Clinical evaluation of youth with pediatric acute-onset neuropsychiatric syndrome (PANS): recommendations from the 2013 PANS Consensus Conference","volume":"25","author":"Chang","year":"2015","journal-title":"J Child Adolesc Psychopharmacol"},{"issue":"5","key":"2021121014050333400_B5","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1542\/hpeds.2014-0017","article-title":"The pediatric inpatient family care conference: a proposed structure toward shared decision-making","volume":"4","author":"Fox","year":"2014","journal-title":"Hosp Pediatr"},{"issue":"4","key":"2021121014050333400_B6","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1517\/14656566.6.4.561","article-title":"Familial dysautonomia: a review of the current pharmacological treatments","volume":"6","author":"Axelrod","year":"2005","journal-title":"Expert Opin Pharmacother"},{"issue":"2","key":"2021121014050333400_B7","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/ana.22297","article-title":"Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia","volume":"69","author":"Lancaster","year":"2011","journal-title":"Ann Neurol"},{"issue":"5","key":"2021121014050333400_B8","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1212\/WNL.0000000000002917","article-title":"The clinical spectrum of Caspr2 antibody-associated disease","volume":"87","author":"van Sonderen","year":"2016","journal-title":"Neurology"},{"issue":"10076","key":"2021121014050333400_B9","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0140-6736(16)31459-3","article-title":"Morvan syndrome as a paraneoplastic disorder of thymoma with anti-CASPR2 antibodies","volume":"389","author":"Vale","year":"2017","journal-title":"Lancet"},{"issue":"5","key":"2021121014050333400_B10","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s11606-006-0067-2","article-title":"Classification and diagnosis of patients with medically unexplained symptoms","volume":"22","author":"Smith","year":"2007","journal-title":"J Gen Intern Med"},{"issue":"1","key":"2021121014050333400_B11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clineuro.2008.09.028","article-title":"Psychogenic non-epileptic seizures--diagnostic issues: a critical review","volume":"111","author":"Bodde","year":"2009","journal-title":"Clin Neurol Neurosurg"},{"issue":"4","key":"2021121014050333400_B12","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.ejpn.2019.03.007","article-title":"Pediatric autoimmune encephalitis in Denmark during 2011-17: a nationwide multicenter population-based cohort study","volume":"23","author":"Boesen","year":"2019","journal-title":"Eur J Paediatr Neurol"},{"issue":"3","key":"2021121014050333400_B13","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/ana.25310","article-title":"LGI1 and CASPR2 neurological autoimmunity in children","volume":"84","author":"L\u00f3pez-Chiriboga","year":"2018","journal-title":"Ann Neurol"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-3786\/1079027\/peds_20193786.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2019-3786\/1079027\/peds_20193786.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T03:46:16Z","timestamp":1639194376000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/145\/6\/e20193786\/76945\/A-Previously-Healthy-Adolescent-With-Acute"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,1]]},"references-count":13,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,6,1]]},"published-print":{"date-parts":[[2020,6,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2019-3786","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,1]]},"article-number":"e20193786"}}