{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T15:25:21Z","timestamp":1781709921477,"version":"3.54.5"},"reference-count":15,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:p>Since the Monkeypox virus outbreak erupted in May 2022, infection has been reported across all ages. Few cases exist in the medical literature about Monkeypox infection in neonates, and little is known about its clinical manifestations, disease course, or side effects of available antiviral agents in this age group. In this report, we describe the case of a 10-day-old neonate from the southern United States who presented with fevers and generalized papulopustular rash. She was treated empirically as a febrile neonate but mpox infection was suspected early because of the characteristic exanthem and its similarity to her mother\u2019s rash that she had developed a few days before the patient\u2019s presentation. Oral tecovirimat was initiated on the third day of admission and mpox was later confirmed by polymerase chain reaction analysis. The patient tolerated oral tecovirimat well and experienced a favorable outcome without lasting effects of infection.<\/jats:p>","DOI":"10.1542\/peds.2023-061198","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T08:13:02Z","timestamp":1703664782000},"source":"Crossref","is-referenced-by-count":9,"title":["A Case of Neonatal Monkeypox Treated With Oral Tecovirimat"],"prefix":"10.1542","volume":"153","author":[{"given":"Sandra","family":"Castejon-Ramirez","sequence":"first","affiliation":[{"name":"aDivision of Infectious Diseases, Le Bonheur Children\u2019s Hospital"},{"name":"bDepartment of Infectious Diseases, St Jude Children\u2019s Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Pennington","sequence":"additional","affiliation":[{"name":"cDepartment of Pediatrics, Le Bonheur Children\u2019s Hospital"},{"name":"dDepartment of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayley","family":"Beene","sequence":"additional","affiliation":[{"name":"cDepartment of Pediatrics, Le Bonheur Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Hysmith","sequence":"additional","affiliation":[{"name":"aDivision of Infectious Diseases, Le Bonheur Children\u2019s Hospital"},{"name":"cDepartment of Pediatrics, Le Bonheur Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley","family":"Ost","sequence":"additional","affiliation":[{"name":"cDepartment of Pediatrics, Le Bonheur Children\u2019s Hospital"},{"name":"dDepartment of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"issue":"1","key":"2024010102552346000_B1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1473-3099(03)00856-9","article-title":"Human monkeypox: an emerging zoonosis","volume":"4","author":"Di Giulio","year":"2004","journal-title":"Lancet Infect Dis"},{"issue":"38","key":"2024010102552346000_B2","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.15585\/mmwr.mm7138e3","article-title":"Monkeypox in a young infant - Florida, 2022","volume":"71","author":"Saunders","year":"2022","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"17","key":"2024010102552346000_B3","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1056\/NEJMc2210828","article-title":"Neonatal monkeypox virus infection","volume":"387","author":"Ramnarayan","year":"2022","journal-title":"N Engl J Med"},{"key":"2024010102552346000_B4","article-title":"Guidance for tecovirimat use","author":"US Centers for Disease Control and Prevention"},{"issue":"2","key":"2024010102552346000_B5","doi-asserted-by":"crossref","first-page":"e0010141","DOI":"10.1371\/journal.pntd.0010141","article-title":"The changing epidemiology of human monkeypox\u2013a potential threat? 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