{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:29:47Z","timestamp":1793492987099,"version":"4.5.0"},"reference-count":16,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,1]]},"abstract":"\n BACKGROUND AND OBJECTIVE<\/jats:title>\n Transient tachypnea of the newborn (TTN) is a common respiratory disorder affecting late-preterm and term infants. Newborns with TTN are typically admitted to the neonatal intensive care unit (NICU) for medical care. Our objective was to reduce NICU length of stay (LOS) for patients with TTN by standardizing care to limit unnecessary intervention.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n We used the Model for Improvement to implement interventions in our level III and IV NICUs and analyzed data using control charts. Interventions included consensus development\/data review, clinical practice guideline implementation, case audits, and an electronic medical record (EMR) order set. Infants aged 35 weeks or more with TTN were included. The primary outcome measure was NICU LOS. Secondary outcome measures were time to first feed, time on respiratory support, incidence of peripheral intravenous (PIV) catheter placement, incidence of intravenous fluid (IVF) administration, incidence of hyponatremia, number of blood draws, and percentage of same-day birth parent\u2013baby discharges. Balancing measures included NICU readmissions, percentage of patients with hypoglycemia, and exposure to breast milk during hospitalization.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n LOS decreased (90 to 51 hours) after study interventions. Time to first feed, time on respiratory support, incidence of hyponatremia, PIV placement, and IVF administration also decreased. Percentage of infants discharged home with their birth parent increased. No changes were noted in any balancing measures.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSION<\/jats:title>\n By prioritizing clinical guideline development, case audits, and EMR implementations, this quality-improvement initiative resulted in decreased LOS and reduced medical interventions for infants with TTN admitted to a level III and level IV NICU.<\/jats:p>\n <\/jats:sec>","DOI":"10.1542\/peds.2025-075231","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:02:25Z","timestamp":1791417745000},"source":"Crossref","is-referenced-by-count":0,"title":["Reducing Intervention and Length of Stay for Neonates With Transient Tachypnea of the Newborn"],"prefix":"10.1542","volume":"158","author":[{"given":"Sushma","family":"Krishna","sequence":"first","affiliation":[{"name":"1Department of Pediatrics, Division of Newborn Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richelle","family":"Reinhart","sequence":"additional","affiliation":[{"name":"1Department of Pediatrics, Division of Newborn Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malorie","family":"Meshkati","sequence":"additional","affiliation":[{"name":"1Department of Pediatrics, Division of Newborn Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"Smith","sequence":"additional","affiliation":[{"name":"2Department of Pediatrics, Division of Newborn Medicine, Mount Sinai Hospital, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidhya","family":"Venkatesan","sequence":"additional","affiliation":[{"name":"2Department of Pediatrics, Division of Newborn Medicine, Mount Sinai Hospital, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney","family":"Juliano","sequence":"additional","affiliation":[{"name":"1Department of Pediatrics, Division of Newborn Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2026,10,8]]},"reference":[{"issue":"1","key":"2026103119565326000_r1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/s41372-020-0757-3","article-title":"Recent advances in pathophysiology and management of transient tachypnea of newborn","volume":"41","author":"Alhassen","year":"2021","journal-title":"J Perinatol."},{"issue":"3","key":"2026103119565326000_r2","doi-asserted-by":"crossref","first-page":"e141","DOI":"10.1542\/neo.18-3-e141","article-title":"Transient tachypnea of the newborn","volume":"18","author":"Hagen","year":"2017","journal-title":"Neoreviews."},{"issue":"175","key":"2026103119565326000_r3","doi-asserted-by":"crossref","first-page":"240112","DOI":"10.1183\/16000617.0112-2024","article-title":"Transient tachypnoea: new concepts on the commonest neonatal respiratory disorder","volume":"34","author":"Neri","year":"2025","journal-title":"Eur Respir Rev."},{"issue":"2","key":"2026103119565326000_r4","first-page":"CD013563","article-title":"Interventions for the management of transient tachypnoea of the newborn - an overview of systematic reviews","volume":"2","author":"Bruschettini","year":"2022","journal-title":"Cochrane Database Syst Rev."},{"key":"2026103119565326000_r5","volume-title":"Essentials of Neonatal Ventilation","author":"PK","year":"2018","edition":"1st ed"},{"issue":"1","key":"2026103119565326000_r6","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jpeds.2011.06.027","article-title":"Randomized controlled trial of restrictive fluid management in transient tachypnea of the newborn","volume":"160","author":"Stroustrup","year":"2012","journal-title":"J Pediatr."},{"issue":"6","key":"2026103119565326000_r7","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1177\/11297298231185536","article-title":"Peripheral intravenous therapy infiltration\/extravasation (PIVIE) risks and the potential for earlier notification of events using a novel sensor technology in a neonatal population","volume":"25","author":"van Rens","year":"2024","journal-title":"J Vasc Access."},{"issue":"15","key":"2026103119565326000_r8","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1002\/bdr2.1530","article-title":"Birth practices: maternal-neonate separation as a source of toxic stress","volume":"111","author":"Bergman","year":"2019","journal-title":"Birth Defects Res."},{"issue":"2","key":"2026103119565326000_r9","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1891\/1058-1243.28.2.108","article-title":"Healthy birth practice #6: keep mother and newborn together-it\u2019s best for mother, newborn, and breastfeeding","volume":"28","author":"Crenshaw","year":"2019","journal-title":"J Perinat Educ."},{"issue":"3","key":"2026103119565326000_r10","doi-asserted-by":"crossref","first-page":"e20161889","DOI":"10.1542\/peds.2016-1889","article-title":"Safe sleep and skin-to-skin care in the neonatal period for healthy term newborns","volume":"138","author":"Feldman-Winter","year":"2016","journal-title":"Pediatrics."},{"issue":"10","key":"2026103119565326000_r11","doi-asserted-by":"crossref","first-page":"e075658","DOI":"10.1136\/bmjopen-2023-075658","article-title":"Investigating short-stay admission to a neonatal intensive care unit as a risk factor for reduced breast feeding at discharge in infants \u226536 weeks\u2019 gestation: a retrospective cohort study","volume":"13","author":"Jones","year":"2023","journal-title":"BMJ Open."},{"key":"2026103119565326000_r12","volume-title":"The Improvement Guide: A Practical Approach to Enhancing Organizational Performance","author":"Langley","year":"2009","edition":"2nd ed"},{"key":"2026103119565326000_r13","volume-title":"The Health Care Data Guide: Learning From Data for Improvement","author":"Provost","year":"2022","edition":"2nd ed"},{"issue":"525","key":"2026103119565326000_r14","first-page":"CS357495","article-title":"Increases in neonatal intensive care admissions in the United States, 2016\u20132023","author":"Martin","year":"2025","journal-title":"NCHS Data Brief."},{"issue":"6","key":"2026103119565326000_r15","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1542\/peds.2012-2809","article-title":"Effect of early limited formula on duration and exclusivity of breastfeeding in at-risk infants: an RCT","volume":"131","author":"Flaherman","year":"2013","journal-title":"Pediatrics."},{"issue":"6","key":"2026103119565326000_r16","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.jpeds.2010.02.022","article-title":"Milk volume on the first day of life","volume":"156","author":"Dollberg","year":"2010","journal-title":"J Pediatr."}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2025-075231\/1973644\/pediatrics.2025075231.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/doi\/10.1542\/peds.2025-075231\/1973644\/pediatrics.2025075231.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T23:56:58Z","timestamp":1793491018000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/158\/5\/e2025075231\/210743\/Reducing-Intervention-and-Length-of-Stay-for"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,8]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,10,8]]},"published-print":{"date-parts":[[2026,11,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2025-075231","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,8]]},"article-number":"e2025075231"}}